Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
undecaprenyl pyrophosphate related proteins
Overview
Regulation of the Bacillus subtilis bcrC bacitracin resistance gene by two extracytoplasmic function sigma factors.
The study identifies bcrC as a crucial gene for bacitracin resistance in Bacillus subtilis, regulated by σ X and σ M. A bcrC mutant showed increased sensitivity to bacitracin, confirming its role in resistance.
New bacitracin-resistant nisin-producing strain of Lactococcus lactis and its physiological characterization.
The study identifies a bacitracin-resistant mutant strain of Lactococcus lactis subsp. lactis (FL-75) with improved nisin A productivity and oxidative stress resistance. The resistance is likely due to increased expression of a gene homologous to the bcrC gene of Bacillus sp.
BceAB-Type Antibiotic Resistance Transporters Appear To Act by Target Protection of Cell Wall Synthesis.
BceAB-type transporters confer resistance against bacitracin by protecting the cell wall synthesis target lipid II from antibiotic binding, rather than importing or inactivating the antibiotic.
From Modules to Networks: a Systems-Level Analysis of the Bacitracin Stress Response in Bacillus subtilis.
The study identifies BcrC and BceAB as key components of the bacitracin resistance network in Bacillus subtilis, demonstrating their roles in maintaining lipid II cycle homeostasis and enhancing resistance to bacitracin.
Surveillance of Enterococcus spp. reveals distinct species and antimicrobial resistance diversity across a One-Health continuum.
The study identified several AMR genes in Enterococcus spp., including erm(B), tet(M), optrA, dfrE, lsa(A), aac(6')-Ib, eat(A), ant(6)-Ia, aph(3')-IIIa, sat4, tet(L), bcrB, bcrC, dfrF, and dfrG, which confer resistance to various antibiotics such as macrolides, tetracyclines, oxazolidinones, trimethoprim, and aminoglycosides.
Complete Genomic Analysis of VRE From a Cattle Feedlot: Focus on 2 Antibiotic Resistance.
The study identified multiple antibiotic resistance genes in vancomycin-resistant enterococci (VRE) isolates from a cattle feedlot, including vanC1, vanC2/C3, vanXY-C, VanR, macA, macB, rlmA (II), erm(A), aac(6')-la, blaEC, tet(A), tet(L), S10p, gyrA, gyrB, msbA, S12p, rpoB, mdfA/cmr, liaF, liaR, liaS, bcrC, mprF, pgsA, ef-G, ef-TU, ddl, alr, kasA, isotRNA, inhA, fabl, murA, folA, and Dfr, which confer resistance to various antibiotics such as vancomycin, macrolides, aminoglycosides, β-lactams, tetracyclines, quinolones, and others.
Biocide-tolerance and antibiotic-resistance in community environments and risk of direct transfers to humans: Unintended consequences of community-wide surface disinfecting during COVID-19?
The paper discusses the mechanisms of biocide tolerance and antibiotic resistance in bacteria, highlighting the role of mutations, horizontal gene transfer, efflux pumps, membrane alterations, and biofilms in developing resistance to disinfectants and antibiotics. It emphasizes the risks posed by the extensive use of disinfectants during the COVID-19 pandemic and the potential for increased antimicrobial resistance.
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