betB

View on PubMed

betaine aldehyde dehydrogenase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to betB

AMR Rules

Browse AMR rules for betB

Validation StatusCandidate

Overview

Validation Method: biochemical validation and chemoproteomics
Drug Classes: carbapenems
Organisms: Acinetobacter baumannii
Papers: 1
Databases: Reslit

Papers1

Heterocyclic Diaryliodonium-Based Inhibitors of Carbapenem-Resistant Acinetobacter baumannii.

PMID 36976008 · 2023

The study identifies betaine aldehyde dehydrogenase (BetB) as a target of the iodonium compound 3a in carbapenem-resistant Acinetobacter baumannii, demonstrating its role in the mechanism of action of the inhibitor.

Gene Information

Gene Name: betB
Allele: betB
Encodes: betaine aldehyde dehydrogenase
Source Database: Reslit
Confers Resistance To: carbapenems
Organisms Tested In: • Acinetobacter baumannii
Validation Method: biochemical validation and chemoproteomics

Comments (0)

No comments yet. Be the first to comment!

betB

Gene Information

Browse AMR Genes

betB

Gene Information