Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
multidrug efflux transporter
Overview
A MATE family multidrug efflux transporter pumps out fluoroquinolones in Bacteroides thetaiotaomicron.
The study identifies bexA, a gene encoding a multidrug efflux transporter belonging to the MATE family, which confers resistance to fluoroquinolones (norfloxacin, ciprofloxacin) and ethidium bromide in Bacteroides thetaiotaomicron and Escherichia coli.
A MATE family multidrug efflux transporter pumps out fluoroquinolones in Bacteroides thetaiotaomicron.
The Bacteroides fragilis pathogenicity island is contained in a putative novel conjugative transposon.
The study identifies satG and bexA as genes conferring resistance to virginiamycin M and fluoroquinolones, respectively, in Bacteroides fragilis strains.
Multidrug Efflux Systems in Microaerobic and Anaerobic Bacteria.
The paper discusses the role of multidrug efflux pumps in microaerobic and anaerobic bacteria, highlighting their importance in antibiotic resistance. Several efflux systems were identified and characterized, including CmeABC, CmeDEF, CmeG, NhaA1/NhaA2, HefABC, HefDEF, HefGHI, NorB, BmeABC1-16, BexA, MdtEF, CusCBA, AcrAB, TolC, TetA, XepCAB, and bcRABD, each contributing to resistance against various antibiotics.
Complete hybrid genome assembly of clinical multidrug-resistant Bacteroides fragilis isolates enables comprehensive identification of antimicrobial-resistance genes and plasmids.
The study identifies multiple antimicrobial resistance genes in multidrug-resistant Bacteroides fragilis isolates, including cfiA, nim, erm, tet, and others, using hybrid genome assembly and ABRicate screening.
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