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bla KPC

Beta-lactamase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to bla KPC

Browse AMR rules for bla KPC

Overview

Drug Classes: carbapenems
Organisms: Klebsiella pneumoniae
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
D179Y	-	-	Klebsiella pneumoniae	carbapenems	Reslit	Candidate

Papers1

1

The Role of Colistin in the Era of New β-Lactam/β-Lactamase Inhibitor Combinations.

PMID 35203879 · 2022

Mutation in the omega loop of the KPC enzyme

Mutation Information

bla KPC: p.D179Y

Protein Change: D179Y
Organisms: Klebsiella pneumoniae
Confers Resistance To: carbapenems
Validation Method: reported in cited literature
Source Database: Reslit