Browse AMR Genes

Explore antimicrobial resistance genes from the literature

bla OXY

beta-lactamase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to bla OXY

Browse AMR rules for bla OXY

Overview

Drug Classes: ceftriaxone
Papers: 1
Mutations: 2

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
-	G1T	-	-	ceftriaxone	Reslit	Candidate
-	G5A	-	-	ceftriaxone	Reslit	Candidate

Papers1

1

Epidemiology and genomic analysis of Klebsiella oxytoca from a single hospital network in Australia.

PMID 36002802 · 2022

Mutations in the promoter region of the chromosomal bla OXY gene lead to overexpression and resistance to third-generation cephalosporins.

Mutation Information

bla OXY: c.G1T bla OXY: c.G5A

Nucleotide Change: G1T, G5A
Confers Resistance To: ceftriaxone
Validation Method: phenotypic testing and whole genome sequencing
Source Database: Reslit