Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
cephalosporin-hydrolyzing class C beta-lactamase ACT-100
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| blaACT-100 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae complex | - | - | OL794654.1 | UHK14157.1 |
| blaACT-101 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae complex | - | - | OL794655.1 | UHK14158.1 |
| blaACT-102 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae complex | - | - | OL794656.1 | UHK14159.1 |
| blaACT-103 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae complex | - | - | OL794660.1 | UHK14163.1 |
| blaACT-104 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae complex | - | - | OL794661.1 | UHK14164.1 |
| blaACT-105 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter asburiae | - | - | OM575023.1 | UMO60338.1 |
| blaACT-106 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Proteus mirabilis | - | - | OM617739.1 | ULU82602.1 |
| blaACT-107 | Card DatabaseReference Gene CatalogReslit | 3 | CEPHALOSPORIN, ampicillin +11 | Enterobacter huaxiensis | Brazilian Atlantic Forest | 2023 | OM967044.1 | UNN26045.1 |
| blaACT-108 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae | - | - | OL445411.1 | UQM99653.1 |
| blaACT-109 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter ludwigii | - | - | OP022995.1 | UTT87806.1 |
| blaACT-110 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter kobei | - | - | LC733682.1 | BDT38917.1 |
| blaACT-111 | Card DatabaseReference Gene CatalogResFinder Database | 3 | UNKNOWN BETA-LACTAM, CEPHALOSPORIN | Enterobacter quasiroggenkampii | - | - | RXSJ01000003.1 | RTM78732.1 |
| blaACT-112 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter ludwigii | - | - | OQ592375.1 | WEG44939.1 |
| blaACT-113 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae | - | - | OQ592376.1 | WEG44940.1 |
| blaACT-114 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter hormaechei | - | - | UNUO01000010.1 | - |
| blaACT-115 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter hormaechei | - | - | CP031726.1 | AXQ35263.1 |
| blaACT-116 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae | - | - | OQ642076.1 | WEY36194.1 |
| blaACT-117 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae | - | - | OQ642077.1 | WEY36195.1 |
| blaACT-118 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae | - | - | OQ642078.1 | WEY36196.1 |
| blaACT-119 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae | - | - | OQ642080.1 | WEY36198.1 |
| blaACT-120 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter hormaechei subsp. hormaechei | - | - | OR398187.1 | WLO97150.1 |
| blaACT-121 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter hormaechei subsp. hormaechei | - | - | OR398188.1 | WLO97151.1 |
| blaACT-122 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter hormaechei subsp. steigerwaltii | - | - | OR398189.1 | WLO97152.1 |
| blaACT-123 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter hormaechei subsp. steigerwaltii | - | - | OR398190.1 | WLO97153.1 |
| blaACT-124 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter hormaechei subsp. steigerwaltii | - | - | OR398191.1 | WLO97154.1 |
| blaACT-125 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter asburiae | - | - | OR880573.1 | WPO27056.1 |
| blaACT-126 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter chuandaensis | - | - | OR880574.1 | WPO27057.1 |
| blaACT-127 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter hormaechei | - | - | OR880575.1 | WPO27058.1 |
| blaACT-128 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter ludwigii | - | - | OR880576.1 | WPO27059.1 |
| blaACT-129 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter ludwigii | - | - | OR880577.1 | WPO27060.1 |
| blaACT-130 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter ludwigii | - | - | OR880578.1 | WPO27061.1 |
| blaACT-131 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter ludwigii | - | - | LRCI01000124.1 | KUQ42458.1 |
| blaACT-132 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter ludwigii | - | - | OR880580.1 | WPO27063.1 |
| blaACT-133 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter ludwigii | - | - | OR880581.1 | WPO27064.1 |
| blaACT-134 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter ludwigii | - | - | OR880582.1 | WPO27065.1 |
| blaACT-135 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter ludwigii | - | - | OR880583.1 | WPO27066.1 |
| blaACT-136 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter ludwigii | - | - | OR880584.1 | WPO27067.1 |
| blaACT-137 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter mori | - | - | OR880585.1 | WPO27068.1 |
| blaACT-138 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter mori | - | - | OR880586.1 | WPO27069.1 |
| blaACT-139 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter mori | - | - | OR880587.1 | WPO27070.1 |
| blaACT-140 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter bugandensis | - | - | DAOHVV010000003.1 | HDR2669832.1 |
| blaACT-141 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter hormaechei subsp. xiangfangensis | - | - | LPPY01000058.1 | KTJ22338.1 |
| blaACT-142 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter kobei | - | - | ABPSFX010000064.1 | EMC7919385.1 |
| blaACT-143 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter sp. ODB01 | - | - | CP015227.1 | AMZ75637.1 |
| blaACT-144 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter hormaechei | - | - | ABGYLI010000008.1 | EJK8937280.1 |
| blaACT-145 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter sp. Crenshaw | - | - | CP020817.3 | AUM01997.1 |
| blaACT-146 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter bugandensis | - | - | ABMQTZ020000010.1 | EMN8661052.1 |
| blaACT-147 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter hormaechei | - | - | CAIZVH010000009.1 | - |
| blaACT-148 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter hormaechei | - | - | FKAD01000003.1 | CZY90887.1 |
| blaACT-149 | Reference Gene Catalog | 1 | CEPHALOSPORIN | uncultured Enterobacter sp. | - | - | CAUSCR010000050.1 | - |
| blaACT-150 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae complex sp. ECL414 | - | - | CP091481.1 | UKB65296.1 |
| blaACT-151 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter hormaechei | - | - | JAHZRO010000014.1 | MBW7688613.1 |
| blaACT-152 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter bugandensis | - | - | CABGRY010000013.1 | - |
| blaACT-153 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter bugandensis | - | - | CP141897.1 | WRT49607.1 |
| blaACT-154 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter kobei | - | - | CP083828.1 | UOY66714.1 |
| blaACT-155 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter hormaechei | - | - | CP090909.1 | UJA58935.1 |
| blaACT-156 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter mori | - | - | JAHZUV010000006.1 | MBW8248988.1 |
| blaACT-157 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter hormaechei | - | - | CP149841.1 | WYI22699.1 |
| blaACT-158 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter hormaechei | - | - | JAJGSG010000001.1 | MCC4544499.1 |
| blaACT-159 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae | - | - | JAJSXK010000010.1 | MCE1398600.1 |
| blaACT-160 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter bugandensis | - | - | JAKMOE010000004.1 | MCK6739931.1 |
| blaACT-161 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter kobei | - | - | JAIOHD010000008.1 | MCO4185007.1 |
| blaACT-162 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter kobei | - | - | JAHWRE010000025.1 | MCS4603851.1 |
| blaACT-163 | Reference Gene Catalog | 1 | CEPHALOSPORIN | - | - | - | JAWNCB010000009.1 | - |
| blaACT-164 | Reference Gene Catalog | 1 | CEPHALOSPORIN | - | - | - | JAWNBH010000014.1 | - |
| blaACT-165 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter bugandensis | - | - | JAXROJ010000007.1 | MEG5635058.1 |
| blaACT-166 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter ludwigii | - | - | JAXRNI010000004.1 | MEG5532466.1 |
| blaACT-167 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter sp. ECC-019 | - | - | PP740475.1 | XAJ73541.1 |
| blaACT-168 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter quasiroggenkampii | - | - | PP740476.1 | XAJ73542.1 |
| blaACT-169 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter kobei | - | - | PP740477.1 | XAJ73543.1 |
| blaACT-170 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter bugandensis | - | - | PP740478.1 | XAJ73544.1 |
| blaACT-171 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter hormaechei subsp. xiangfangensis | - | - | PP740479.1 | XAJ73545.1 |
| blaACT-172 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter bugandensis | - | - | PP740480.1 | XAJ73546.1 |
| blaACT-173 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter sp. ECC-249 | - | - | PP740481.1 | XAJ73547.1 |
| blaACT-174 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter hormaechei subsp. xiangfangensis | - | - | PP740482.1 | XAJ73548.1 |
| blaACT-175 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter bugandensis | - | - | PP740483.1 | XAJ73549.1 |
| blaACT-176 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter sichuanensis | - | - | PP740484.1 | XAJ73550.1 |
| blaACT-177 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter asburiae | - | - | PP740485.1 | XAJ73551.1 |
| blaACT-178 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter hormaechei subsp. xiangfangensis | - | - | PP740486.1 | XAJ73552.1 |
| blaACT-179 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter hormaechei subsp. xiangfangensis | - | - | PP740487.1 | XAJ73553.1 |
| blaACT-180 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter sichuanensis | - | - | PP740488.1 | XAJ73554.1 |
| blaACT-181 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter kobei | - | - | PP740489.1 | XAJ73555.1 |
| blaACT-182 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter asburiae | - | - | PP740490.1 | XAJ73556.1 |
| blaACT-183 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter hormaechei subsp. xiangfangensis | - | - | PP740491.1 | XAJ73557.1 |
| blaACT-184 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter hormaechei subsp. xiangfangensis | - | - | PP740492.1 | XAJ73558.1 |
| blaACT-185 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter kobei | - | - | PP740493.1 | XAJ73559.1 |
| blaACT-186 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter hormaechei subsp. xiangfangensis | - | - | PP740494.1 | XAJ73560.1 |
| blaACT-187 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter quasiroggenkampii | - | - | PP740495.1 | XAJ73561.1 |
| blaACT-188 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter bugandensis | - | - | PP740496.1 | XAJ73562.1 |
| blaACT-189 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter hormaechei subsp. xiangfangensis | - | - | PP740497.1 | XAJ73563.1 |
| blaACT-190 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter kobei | - | - | PP740498.1 | XAJ73564.1 |
| blaACT-191 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter hormaechei subsp. xiangfangensis | - | - | PP740499.1 | XAJ73565.1 |
| blaACT-192 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter hormaechei subsp. hoffmannii | - | - | PP740500.1 | XAJ73566.1 |
| blaACT-193 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter sichuanensis | - | - | PP740501.1 | XAJ73567.1 |
| blaACT-194 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter hormaechei subsp. xiangfangensis | - | - | PP740502.1 | XAJ73568.1 |
| blaACT-195 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter cloacae | - | - | PV075156.1 | XOU30620.1 |
| blaACT-196 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter cloacae | - | - | PV075157.1 | XOU30621.1 |
| blaACT-197 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter cloacae | - | - | PV075158.1 | XOU30622.1 |
| blaACT-198 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter cloacae | - | - | PV075159.1 | XOU30623.1 |
| blaACT-199 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter hormaechei | - | - | PV075160.1 | XOU30624.1 |
| blaACT-200 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter hormaechei | - | - | PV075161.1 | XOU30625.1 |
| blaACT-201 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter hormaechei | - | - | PV075162.1 | XOU30626.1 |
| blaACT-202 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter hormaechei | - | - | PV075163.1 | XOU30627.1 |
| blaACT-203 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter hormaechei | - | - | PV075164.1 | XOU30628.1 |
| blaACT-204 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter sp. | - | - | PV075165.1 | XOU30629.1 |
| blaACT-205 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter hormaechei | - | - | PV075166.1 | XOU30630.1 |
| blaACT-206 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter hormaechei | - | - | PV075167.1 | XOU30631.1 |
| blaACT-207 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter hormaechei | - | - | PV075168.1 | XOU30632.1 |
| blaACT-208 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter hormaechei | - | - | PV075169.1 | XOU30633.1 |
| blaACT-209 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter bugandensis | - | - | PV075171.1 | XOU30635.1 |
| blaACT-210 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter bugandensis | - | - | PV075172.1 | XOU30636.1 |
| blaACT-211 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter sp. | - | - | PV075174.1 | XOU30638.1 |
| blaACT-212 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter kobei | - | - | PV075175.1 | XOU30639.1 |
| blaACT-213 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter kobei | - | - | PV075176.1 | XOU30640.1 |
| blaACT-214 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter cloacae | - | - | AJ278994.1 | CAC08444.1 |
| blaACT-215 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Enterobacter cloacae complex sp. Mu1197 | - | - | CP157375.1 | XBM30897.1 |
| blaACT-24 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae | - | - | KJ207207.1 | AHL39336.1 |
| blaACT-25 | Card DatabaseReference Gene CatalogReslit | 5 | CEPHALOSPORIN, ampicillin +3 | Enterobacter cloacae +3 | Southeast Nigeria, Nigeria, Sri Lanka | 2022, 2023, 2025 | KJ207208.1 | AHL39338.1 |
| blaACT-27 | Card DatabaseReference Gene CatalogReslit | 3 | CEPHALOSPORIN, piperacillin tazobactam | Enterobacter cloacae +5 | Australia|Singapore|Turkey | 2021 | KJ207209.1 | AHL39340.1 |
| blaACT-28 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae | - | - | KJ207206.1 | AHL39333.1 |
| blaACT-29 | Card DatabaseReference Gene CatalogReslit | 3 | CEPHALOSPORIN, beta lactams | Enterobacter asburiae +2 | Danakil Depression, Afar Region, Ethiopia | 2023 | KM087832.1 | AIT76085.1 |
| blaACT-30 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae | - | - | KM087833.1 | AIT76086.1 |
| blaACT-31 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae | - | - | KM087843.1 | AIT76096.1 |
| blaACT-32 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae | - | - | KM087835.1 | AIT76088.1 |
| blaACT-33 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae | - | - | KM087834.1 | AIT76087.1 |
| blaACT-35 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae | - | - | LC004922.1 | BAP68758.1 |
| blaACT-36 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae | - | - | KM926621.1 | AJG06170.1 |
| blaACT-37 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae | - | - | KM926622.1 | AJG06172.1 |
| blaACT-38 | Card DatabaseReference Gene CatalogReslit | 3 | CEPHALOSPORIN, piperacillin tazobactam | Citrobacter freundii +4 | Australia|Singapore|Turkey | 2021 | KP836350.1 | AKS43590.1 |
| blaACT-39 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter cloacae | - | - | KU884289.1 | AMP42993.1 |
| blaACT-4 | Card DatabaseReference Gene CatalogResFinder Database | 3 | CEPHALOSPORIN, TICARCILLIN +10 | Enterobacter asburiae | - | - | EU427302.2 | ABZ81086.1 |
| blaACT-40 | Card DatabaseReference Gene CatalogReslit | 4 | CEPHALOSPORIN, piperacillin tazobactam | Enterobacter cloacae +5 | Australia|Singapore|Turkey | 2021 | KX192159.1 | ANE37563.1 |
| blaACT-41 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter cloacae | - | - | KX192160.1 | ANE37564.1 |
| blaACT-42 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter cloacae | - | - | KX192161.1 | ANE37565.1 |
| blaACT-43 | Card DatabaseReference Gene CatalogReslit | 4 | CEPHALOSPORIN, piperacillin tazobactam | Enterobacter cloacae +5 | Australia|Singapore|Turkey | 2021 | KX192162.1 | ANE37566.1 |
| blaACT-44 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter cloacae | - | - | KX192163.1 | ANE37567.1 |
| blaACT-45 | Card DatabaseReference Gene CatalogReslit | 4 | CEPHALOSPORIN, cephalosporins | Enterobacter cloacae +1 | southwestern Nigeria | 2025 | KX192164.1 | ANE37568.1 |
| blaACT-46 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter cloacae | - | - | KX192166.1 | ANE37570.1 |
| blaACT-47 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter hormaechei | - | - | KX192170.1 | ANE37574.1 |
| blaACT-48 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter asburiae | - | 2018 | KX192158.1 | ANE37562.1 |
| blaACT-49 | Card DatabaseReference Gene CatalogReslit | 4 | CEPHALOSPORIN, piperacillin tazobactam | Enterobacter bugandensis +5 | Australia|Singapore|Turkey | 2021 | KX192167.1 | ANE37571.1 |
| blaACT-50 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter sichuanensis | - | - | KX192168.1 | ANE37572.1 |
| blaACT-51 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter kobei | - | - | KX192169.1 | ANE37573.1 |
| blaACT-52 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter kobei | - | - | KX192171.1 | ANE37575.1 |
| blaACT-53 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter kobei | - | - | MF576300.1 | ASP63120.1 |
| blaACT-54 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter cloacae | - | - | MG028658.1 | ATJ25948.1 |
| blaACT-55 | Card DatabaseReference Gene CatalogReslit | 4 | CEPHALOSPORIN, piperacillin tazobactam | Enterobacter hormaechei subsp. oharae +5 | Australia|Singapore|Turkey | 2021 | MH469274.1 | AWY87649.1 |
| blaACT-56 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter hormaechei subsp. steigerwaltii | - | - | MH469275.1 | AWY87650.1 |
| blaACT-57 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter asburiae | - | - | MH469278.1 | AWY87653.1 |
| blaACT-58 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter cloacae complex sp. | - | - | MH469279.1 | AWY87654.1 |
| blaACT-59 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter hormaechei subsp. oharae | - | - | MH469280.1 | AWY87655.1 |
| blaACT-60 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter hormaechei subsp. oharae | - | - | MH469281.1 | AWY87656.1 |
| blaACT-61 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter hormaechei subsp. oharae | - | - | MH469283.1 | AWY87658.1 |
| blaACT-62 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter cloacae complex sp. | - | - | MH469270.1 | AWY87659.1 |
| blaACT-63 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter cloacae complex sp. | - | - | MH469271.1 | AWY87660.1 |
| blaACT-64 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter kobei | - | - | MH469272.1 | AWY87661.1 |
| blaACT-65 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter hormaechei subsp. steigerwaltii | - | - | MK532282.1 | QBF38560.1 |
| blaACT-66 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter hormaechei subsp. hoffmannii | - | - | MK532283.1 | QBF38561.1 |
| blaACT-67 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter hormaechei subsp. hoffmannii | - | - | MK532284.1 | QBF38562.1 |
| blaACT-68 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter asburiae | - | - | MK568456.1 | QBG64270.1 |
| blaACT-69 | Card DatabaseReference Gene CatalogReslit | 4 | CEPHALOSPORIN, cephalosporins +1 | Enterobacter hormaechei +2 | India | 2024 | MN082687.1 | QDH43116.1 |
| blaACT-7 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 13 | TICARCILLIN, CEPHALOSPORIN +22 | Klebsiella pneumoniae +7 | China, Tokyo, Japan|Japan, Guadeloupe (French West Indies)|Guadeloupe, Germany, Europe | 2018, 2020, 2021, 2022, 2023, 2024, 2026 | FJ237368.1 | ACJ05688.1 |
| blaACT-70 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter hormaechei | - | - | MN082688.1 | QDH43117.1 |
| blaACT-72 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter cloacae | - | - | MN082690.1 | QDH43119.1 |
| blaACT-74 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter hormaechei subsp. steigerwaltii | - | - | LPQA01000012.1 | KTJ29119.1 |
| blaACT-76 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter bugandensis | - | - | RXPM01000003.1 | RUO01826.1 |
| blaACT-77 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter cloacae | - | - | MN692201.1 | QGQ32906.1 |
| blaACT-78 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter cloacae | - | - | MN862370.1 | QHD57400.1 |
| blaACT-79 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter cloacae | - | - | MN862371.1 | QHD57401.1 |
| blaACT-8 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Escherichia coli | - | - | FN645445.1 | CBI75448.1 |
| blaACT-80 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter cloacae | - | - | MN862372.1 | QHD57402.1 |
| blaACT-81 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter cloacae | - | - | MN862373.1 | QHD57403.1 |
| blaACT-82 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter cloacae | - | - | MN862374.1 | QHD57404.1 |
| blaACT-83 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter hormaechei | - | - | MT040967.1 | QIC04101.1 |
| blaACT-84 | Card DatabaseReference Gene CatalogReslit | 4 | CEPHALOSPORIN, cephalosporins | Enterobacter asburiae +1 | Brazil | 2021 | MT136764.1 | QIH98458.1 |
| blaACT-87 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter kobei | - | - | LC545448.1 | BCG11505.1 |
| blaACT-88 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter ludwigii | - | - | MW887657.1 | QTV32571.1 |
| blaACT-90 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter hormaechei subsp. hoffmannii UCICRE 3 | - | - | AYIM01000001.1 | ESM21743.1 |
| blaACT-91 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae | - | - | OL351615.1 | UEG31054.1 |
| blaACT-92 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae | - | - | OL351616.1 | UEG31055.1 |
| blaACT-93 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae | - | - | OL351618.1 | UEG31057.1 |
| blaACT-94 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae | - | - | OL351619.1 | UEG31058.1 |
| blaACT-95 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae complex | - | - | OL794635.1 | UHK14138.1 |
| blaACT-96 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae complex | - | - | OL794638.1 | UHK14141.1 |
| blaACT-97 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae complex | - | - | OL794641.1 | UHK14144.1 |
| blaACT-98 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae complex | - | - | OL794648.1 | UHK14151.1 |
| blaACT-99 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae complex | - | - | OL794649.1 | UHK14152.1 |
| blaMIR-14 | Card DatabaseReference Gene CatalogReslit | 4 | CEPHALOSPORIN, aztreonam | Enterobacter asburiae +1 | Nigeria | 2025 | KM087864.1 | AIT76117.1 |
| blaACT-16 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 11 | TICARCILLIN, CEPHALOSPORIN +18 | Enterobacter cloacae +10 | Tokyo, Japan|Japan, Guadeloupe (French West Indies)|Guadeloupe, Australia|Singapore|Turkey, India, Europe|Asia|South America|Africa|Germany|Vietnam|USA|Ecuador|China, Atlanta, China | 2014, 2021, 2024, 2025, 2026 | AB737978.1 | BAM34463.1 |
| blaACT-34 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter cloacae | - | 2014 | NG_048621.1 | WP_063857778.1 |
| blaACT-73 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter cloacae | - | 2014 | NG_066689.2 | WP_152315464.1 |
| blaACT-75 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter hormaechei subsp. xiangfangensis | - | 2016 | NG_066691.1 | WP_045347148.1 |
| blaACT-9 | Card DatabaseResFinder DatabaseReslit | 6 | ertapenem, TICARCILLIN +15 | Pantoea agglomerans +2 | Brazil, Czech Republic, China | 2011, 2021, 2023, 2026 | HQ693810.1 | AEI70575.1 |
| blaACT-GC1 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Enterobacter cloacae | - | 1995 | D44479.1 | BAA07922.1 |
| blaACT-89 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter hormaechei | - | 2001 | MZ067484.1 | QUR41147.1 |
| blaACT-1 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 15 | cefoxitin, ceftriaxone +18 | Klebsiella pneumoniae +9 | United States, New York City, Eastern Europe|India|Latin America|Asia Pacific|North America|Western Europe, China, Tokyo, Japan|Japan, Eastern China | 1997, 2002, 2003, 2005, 2006, 2009, 2010, 2013, 2021, 2023 | AF055067|X77455|X91840|U58495|X04730 | AAC45086.2 |
| blaACT-3 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 6 | TICARCILLIN, CEPHALOSPORIN +15 | Klebsiella pneumoniae +1 | Shanghai, China, China | 2009, 2017, 2025 | EF125013.1 | ABL67017.1 |
| blaACT-6 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 6 | cefoxitin, cefotaxime +16 | Klebsiella pneumoniae +1 | China, Czech Republic | 2011, 2023 | FJ237366 | ACJ05686.1 |
| blaACT-2 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 8 | TICARCILLIN, CEPHALOSPORIN +17 | Enterobacter asburiae +6 | Thailand, Australia|Singapore|Turkey, Bangladesh, China | 2013, 2019, 2021, 2025, 2026 | AM076977.1 | CAJ28994.1 |
| blaACT-5 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 7 | TICARCILLIN, CEPHALOSPORIN +16 | Escherichia coli +6 | China, Tokyo, Japan|Japan | 2013, 2019, 2021, 2026 | FJ237369.1 | ACJ05689.1 |
| ACT/MIR | Reslit | 1 | ceftazidime, cefotaxime +1 | Escherichia coli | Netherlands|Asia|South Asia|East Asia | 2013 | - | - |
| blaACT-13 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter asburiae | - | 2014 | HE819402.1 | CCK86741.1 |
| blaACT-23 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae | - | 2014 | KF515536.1 | AGU38146.1 |
| blaACT-20 | Card DatabaseReference Gene CatalogReslit | 3 | CEPHALOSPORIN, cefotaxime +3 | Enterobacter hormaechei +1 | Shanghai, China | 2014, 2017 | KF526117.1 | AHA80105.1 |
| blaACT-21 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter hormaechei | - | 2014 | KF526118.1 | AHA80106.1 |
| blaACT-10 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 5 | TICARCILLIN, CEPHALOSPORIN +11 | Serratia marcescens +1 | Czech Republic | 2014, 2023 | JN848330.1 | AEV91214.1 |
| blaACT-12 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 7 | TICARCILLIN, CEPHALOSPORIN +16 | Enterobacter cloacae +7 | Australia|Singapore|Turkey, Atlanta, China | 2015, 2021, 2025, 2026 | JX440355.1 | AFU25650.1 |
| blaACT-14 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 7 | TICARCILLIN, CEPHALOSPORIN +14 | Enterobacter cloacae +2 | Germany, Ireland, Europe | 2015, 2022, 2023, 2025 | JX440354.1 | AFU25647.1 |
| blaACT-15 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 11 | TICARCILLIN, CEPHALOSPORIN +21 | Enterobacter cloacae +9 | Guadeloupe (French West Indies)|Guadeloupe, Australia|Singapore|Turkey, Germany, Shanghai, China, Brazil, China | 2015, 2021, 2022, 2023, 2024, 2026 | JX440356.1 | AFU25653.1 |
| blaACT-17 | Card DatabaseReference Gene CatalogReslit | 5 | CEPHALOSPORIN, piperacillin tazobactam +7 | Enterobacter cloacae +7 | Australia|Singapore|Turkey, Europe | 2015, 2021, 2023, 2024 | KF992026.1 | AHM76771.1 |
| blaACT-18 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae | - | 2015 | KF992028.1 | AHM76777.1 |
| blaACT-19 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae | - | 2015 | KF992029.1 | AHM76779.1 |
| blaACT-22 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter cloacae | - | 2015 | KF992027.1 | AHM76774.1 |
| ACT | Reslit | 6 | cephalosporins, cefotaxime +4 | Enterobacter cloacae +3 | South Korea, Delhi, India, International Space Station, Hungary | 2017, 2019, 2020, 2024 | KY706079|KY706080|KY753816 | - |
| blaACT-86 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter hormaechei | - | 2018 | WHOQ01000125.1 | MPV43777.1 |
| bla_Act | Reslit | 1 | cephalosporins | Escherichia coli | Germany|Kosovo|Ukraine|Afghanistan | 2023 | - | - |
| bla_ACT-28 | Reslit | 1 | carbapenems | Enterobacter kobei +1 | - | 2019 | MH469272 | - |
| ACT-MIR | Reslit | 1 | cephalosporins | Escherichia coli | Tanzania|Thailand|human|swine | 2019 | - | - |
| blaACT-85 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Enterobacter hormaechei | - | 2020 | WJXX01000007.1 | MRN75760.1 |
| blaACT | Reslit | 9 | ampicillin, ceftriaxone +7 | Enterobacter cloacae +6 | Egypt, Guadeloupe (French West Indies)|Guadeloupe, Kuwait, Western Province of Sri Lanka, United States, Austria, Southern Thailand, Calgary, Canada|Calgary, Alberta, Canada, China|Thailand|USA|Spain|Norway|Japan|Vietnam|Hong Kong | 2021, 2022, 2023, 2024, 2025 | NZ_CP012165.1|NC_014121.1|SAMN15680734|SAMN15680735|SAMN15680736|SAMN15680737|SAMN15680738|SAMN15680739|SAMN15680740|SAMN15680741|SAMN15680742|SAMN15680743|SAMN15680744|SAMN15680745|SAMN15680746|SAMN15680747|SAMN15680748|SAMN15680749|SAMN15680750|SAMN15680751|SAMN15680752|SAMN15680753|SAMN15680754|SAMN15680755|SAMN15680756|SAMN15680757|SAMN15680758|SAMN15680759|SAMN15680760|SAMN15680761 | - |
| blaACT–7 | Reslit | 1 | ceftazidime, cefotaxime | Enterobacter quasiroggenkampii +6 | Edo state, Nigeria | 2022 | JAIKTX000000000|JAIKUW000000000|JAIKTX010000000|JAIKUW010000000 | - |
| blaACT–25 | Reslit | 1 | ceftazidime, cefotaxime | Enterobacter quasiroggenkampii +6 | Edo state, Nigeria | 2022 | JAIKTX000000000|JAIKUW000000000|JAIKTX010000000|JAIKUW010000000 | - |
| blaACT- type | Reslit | 1 | ceftazidime | Enterobacterales | Germany | 2023 | - | - |
Extension of resistance to cefepime and cefpirome associated to a six amino acid deletion in the H-10 helix of the cephalosporinase of an Enterobacter cloacae clinical isolate.
Extension of resistance to cefepime and cefpirome associated to a six amino acid deletion in the H-10 helix of the cephalosporinase of an Enterobacter cloacae clinical isolate.
Occurrence of newer beta-lactamases in Klebsiella pneumoniae isolates from 24 U.S. hospitals.
The study identified several beta-lactamases, including bla DHA-1, bla ACT-1, bla FOX-5, bla CMY-2, and bla KPC-2, in Klebsiella pneumoniae isolates from 24 U.S. hospitals. These enzymes confer resistance to various beta-lactam antibiotics.
Occurrence of extended-spectrum and AmpC beta-lactamases in bloodstream isolates of Klebsiella pneumoniae: isolates harbor plasmid-mediated FOX-5 and ACT-1 AmpC beta-lactamases.
The study identifies plasmid-mediated bla FOX-5 and bla ACT-1 AmpC beta-lactamases in bloodstream isolates of Klebsiella pneumoniae, highlighting their role in resistance to cephalosporins and cefoxitin.
Practical methods using boronic acid compounds for identification of class C beta-lactamase-producing Klebsiella pneumoniae and Escherichia coli.
The study identifies and characterizes several plasmid-mediated class C beta-lactamases, including CMY-2, CMY-8, CMY-9, FOX-5, MOX-1, ACT-1, and LAT-1, which confer resistance to ceftazidime and cefotaxime in Escherichia coli and Klebsiella pneumoniae. The researchers developed practical methods using boronic acid compounds, such as 3-aminophenylboronic acid (APB), to detect these beta-lactamases.
High-level carbapenem resistance in a Klebsiella pneumoniae clinical isolate is due to the combination of blaACT-1 beta-lactamase production, porin OmpK35/36 insertional inactivation, and down-regulation of the phosphate transport porin phoe.
High-level carbapenem resistance in a Klebsiella pneumoniae clinical isolate is due to the combination of blaACT-1 beta-lactamase production, porin OmpK35/36 insertional inactivation, and down-regulation of the phosphate transport porin phoe.
ACT-3, a novel plasmid-encoded class C beta-lactamase in a Klebsiella pneumoniae isolate from China.
ACT-3, a novel plasmid-encoded class C beta-lactamase in a Klebsiella pneumoniae isolate from China.
ACT-3, a novel plasmid-encoded class C beta-lactamase in a Klebsiella pneumoniae isolate from China.
ACT-3, a novel plasmid-encoded class C beta-lactamase in a Klebsiella pneumoniae isolate from China.
Characterization and sequence analysis of extended-spectrum-{beta}-lactamase-encoding genes from Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis isolates collected during tigecycline phase 3 clinical trials.
The study identified various extended-spectrum beta-lactamase (ESBL) genes, including bla CTX-M-1, bla CTX-M-2, bla CTX-M-5, bla CTX-M-15, bla CTX-M-22, bla CTX-M-28, bla SHV-5, bla SHV-12, bla TEM-1, bla OXA-1, bla OXA-2, bla OXA-5, bla PER-1, bla ACT-1, bla MIR-1, bla CMY-2, bla FOX-1, bla DHA-1, and bla KPC-2, in Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis isolates.
Phenotypic and biochemical comparison of the carbapenem-hydrolyzing activities of five plasmid-borne AmpC beta-lactamases.
The study characterizes the carbapenem-hydrolyzing activities of five plasmid-borne AmpC beta-lactamases (CMY-2, ACT-1, DHA-1, FOX-1, and ACC-1) and shows that CMY-2, ACT-1, and DHA-1 confer resistance to imipenem, while FOX-1 and ACC-1 do not.
ACT-6, a novel plasmid-encoded class C beta-lactamase in a Klebsiella pneumoniae isolate from China.
The study identified ACT-6, a novel plasmid-encoded class C beta-lactamase in a Klebsiella pneumoniae isolate from China, which confers resistance to various β-lactam antibiotics.
ACT-6, a novel plasmid-encoded class C β-lactamase in a Klebsiella pneumoniae isolate from China.
ACT-6, a novel plasmid-encoded class C β-lactamase in a Klebsiella pneumoniae isolate from China.
ACT-6, a novel plasmid-encoded class C β-lactamase in a Klebsiella pneumoniae isolate from China.
Impact of derepressed AmpC beta-lactamase ACT-9 on the clinical efficacy of ertapenem.
Impact of derepressed AmpC beta-lactamase ACT-9 on the clinical efficacy of ertapenem.
Prevalence and genotypic analysis of plasmid-mediated β-lactamases among urinary Klebsiella pneumoniae isolates in Moroccan community.
Prevalence and genotypic analysis of plasmid-mediated β-lactamases among urinary Klebsiella pneumoniae isolates in Moroccan community.
Prevalence and genotypic analysis of plasmid-mediated β-lactamases among urinary Klebsiella pneumoniae isolates in Moroccan community.
Identification of ACT-1 plasmid-mediated AmpC beta-lactamase producing Citrobacter freundii from a Chinese patient.
The study identifies the first report of a Citrobacter freundii isolate producing the ACT-1 plasmid-mediated AmpC beta-lactamase, highlighting the potential for horizontal gene transfer and multidrug resistance.
Prevalence and types of extended spectrum β-lactamases among urinary Escherichia coli isolates in Moroccan community.
Prevalence and types of extended spectrum β-lactamases among urinary Escherichia coli isolates in Moroccan community.
Prevalence and types of extended spectrum β-lactamases among urinary Escherichia coli isolates in Moroccan community.
Extended-spectrum beta-lactamase-producing enterobacteriaceae among travelers from the Netherlands.
The study identified CTX-M-15-like, CTX-M-1, CTX-M-3, CTX-M-32, CTX-M-9, SHV-ESBL, CMY-2, and ACT/MIR beta-lactamases as the primary mechanisms of extended-spectrum beta-lactamase (ESBL) resistance in Enterobacteriaceae among travelers from the Netherlands.
GES-5 among the β-lactamases detected in ubiquitous bacteria isolated from aquatic environment samples.
GES-5 among the β-lactamases detected in ubiquitous bacteria isolated from aquatic environment samples.
Characterization of novel plasmid-mediated β-lactamases (SHV-167 and ACT-16) associated with New Delhi metallo-β-lactamase-1 harbouring isolates from neonates in India.
Characterization of novel plasmid-mediated β-lactamases (SHV-167 and ACT-16) associated with New Delhi metallo-β-lactamase-1 harbouring isolates from neonates in India.
Enterobacter cloacae with a novel variant of ACT AmpC beta-lactamase originating from glaucous gull (Larus hyperboreus) in Svalbard.
Enterobacter cloacae with a novel variant of ACT AmpC beta-lactamase originating from glaucous gull (Larus hyperboreus) in Svalbard.
New broad-spectrum β-lactamases emerging among Enterobacteriaceae from healthy cats and dogs: a public health concern?
New broad-spectrum β-lactamases emerging among Enterobacteriaceae from healthy cats and dogs: a public health concern?
New broad-spectrum β-lactamases emerging among Enterobacteriaceae from healthy cats and dogs: a public health concern?
New broad-spectrum β-lactamases emerging among Enterobacteriaceae from healthy cats and dogs: a public health concern?
Avibactam and class C β-lactamases: mechanism of inhibition, conservation of the binding pocket, and implications for resistance.
Avibactam and class C β-lactamases: mechanism of inhibition, conservation of the binding pocket, and implications for resistance.
First description of OXA-48 carbapenemase harbored by Escherichia coli and Enterobacter cloacae from a single patient in Portugal.
First description of OXA-48 carbapenemase harbored by Escherichia coli and Enterobacter cloacae from a single patient in Portugal.
ACT-10, a novel plasmid-encoded class C β-lactamase in a Serratia marcescens isolate from China.
ACT-10, a novel plasmid-encoded class C β-lactamase in a Serratia marcescens isolate from China.
ACT-10, a novel plasmid-encoded class C β-lactamase in a Serratia marcescens isolate from China.
Characterization of Beta-lactamases in Faecal Enterobacteriaceae Recovered from Healthy Humans in Spain: Focusing on AmpC Polymorphisms.
Characterization of Beta-lactamases in Faecal Enterobacteriaceae Recovered from Healthy Humans in Spain: Focusing on AmpC Polymorphisms.
Characterization of Beta-lactamases in Faecal Enterobacteriaceae Recovered from Healthy Humans in Spain: Focusing on AmpC Polymorphisms.
Characterization of Beta-lactamases in Faecal Enterobacteriaceae Recovered from Healthy Humans in Spain: Focusing on AmpC Polymorphisms.
Characterization of Beta-lactamases in Faecal Enterobacteriaceae Recovered from Healthy Humans in Spain: Focusing on AmpC Polymorphisms.
Characterization of Beta-lactamases in Faecal Enterobacteriaceae Recovered from Healthy Humans in Spain: Focusing on AmpC Polymorphisms.
Characterization of Beta-lactamases in Faecal Enterobacteriaceae Recovered from Healthy Humans in Spain: Focusing on AmpC Polymorphisms.
Characterization of Beta-lactamases in Faecal Enterobacteriaceae Recovered from Healthy Humans in Spain: Focusing on AmpC Polymorphisms.
Characterization of Beta-lactamases in Faecal Enterobacteriaceae Recovered from Healthy Humans in Spain: Focusing on AmpC Polymorphisms.
Characterization of Beta-lactamases in Faecal Enterobacteriaceae Recovered from Healthy Humans in Spain: Focusing on AmpC Polymorphisms.
Characterization of Beta-lactamases in Faecal Enterobacteriaceae Recovered from Healthy Humans in Spain: Focusing on AmpC Polymorphisms.
Characterization of Beta-lactamases in Faecal Enterobacteriaceae Recovered from Healthy Humans in Spain: Focusing on AmpC Polymorphisms.
Characterization of Beta-lactamases in Faecal Enterobacteriaceae Recovered from Healthy Humans in Spain: Focusing on AmpC Polymorphisms.
Characterization of Beta-lactamases in Faecal Enterobacteriaceae Recovered from Healthy Humans in Spain: Focusing on AmpC Polymorphisms.
Characterization of Beta-lactamases in Faecal Enterobacteriaceae Recovered from Healthy Humans in Spain: Focusing on AmpC Polymorphisms.
Characterization of Beta-lactamases in Faecal Enterobacteriaceae Recovered from Healthy Humans in Spain: Focusing on AmpC Polymorphisms.
Characterization of Beta-lactamases in Faecal Enterobacteriaceae Recovered from Healthy Humans in Spain: Focusing on AmpC Polymorphisms.
Characterization of Beta-lactamases in Faecal Enterobacteriaceae Recovered from Healthy Humans in Spain: Focusing on AmpC Polymorphisms.
Characterization of Beta-lactamases in Faecal Enterobacteriaceae Recovered from Healthy Humans in Spain: Focusing on AmpC Polymorphisms.
Characterization of Beta-lactamases in Faecal Enterobacteriaceae Recovered from Healthy Humans in Spain: Focusing on AmpC Polymorphisms.
Comprehensive Genome Analysis of Carbapenemase-Producing Enterobacter spp.: New Insights into Phylogeny, Population Structure, and Resistance Mechanisms.
Comprehensive Genome Analysis of Carbapenemase-Producing Enterobacter spp.: New Insights into Phylogeny, Population Structure, and Resistance Mechanisms.
Development of a Rapid Reverse Blot Hybridization Assay for Detection of Clinically Relevant Antibiotic Resistance Genes in Blood Cultures Testing Positive for Gram-Negative Bacteria.
The study developed and evaluated the REBA-EAC assay for the rapid detection of clinically relevant antibiotic resistance genes in blood cultures positive for Gram-negative bacteria. The assay successfully identified various beta-lactamase genes, including ESBLs (CTX-M, TEM, SHV), AmpC beta-lactamases (DHA, CMY-2-like, ACT), and carbapenemases (IMP, VIM, NDM, KPC, OXA-48-like, SPM).
Distribution of Integrons and Phylogenetic Groups among Enteropathogenic Escherichia coli Isolates from Children <5 Years of Age in Delhi, India.
The study identified various AMR genes including dfrA1, dfrA7, dfrA12, aadA1, aadA2, sul1, tetA, aacC1, TEM, SHV, CTX-M, OXA, NDM-1, IMP, VIM, ACT, DHA, and CMY in E. coli isolates from children in Delhi, India. These genes were associated with resistance to multiple antibiotics such as trimethoprim, streptomycin, sulfonamides, tetracycline, gentamicin, and various beta-lactams.
Antimicrobial susceptibility and molecular epidemiology of clinical Enterobacter cloacae bloodstream isolates in Shanghai, China.
The study identified several AMR genes in Enterobacter cloacae bloodstream isolates, including ESBLs (SHV-12, CTX-M-15, CTX-M-65), carbapenemases (IMP-26, NDM-1), plasmid-mediated AmpC beta-lactamases (ACT-20, ACT-3, DHA-1), and TEM-1. These genes were associated with resistance to various antibiotics, highlighting the need for continued surveillance.
Antimicrobial susceptibility and molecular epidemiology of clinical Enterobacter cloacae bloodstream isolates in Shanghai, China.
The study identified several AMR genes in Enterobacter cloacae bloodstream isolates, including ESBLs (SHV-12, CTX-M-15, CTX-M-65), carbapenemases (IMP-26, NDM-1), plasmid-mediated AmpC beta-lactamases (ACT-20, ACT-3, DHA-1), and TEM-1. These genes were associated with resistance to various antibiotics, highlighting the need for continued surveillance.
The Nigerian catfish (Clarias gariepinus) pisciculture systems: reservoirs of multidrug-resistant bacteria.
Selection of mutants with resistance or diminished susceptibility to ceftazidime/avibactam from ESBL- and AmpC-producing Enterobacteriaceae.
Selection of mutants with resistance or diminished susceptibility to ceftazidime/avibactam from ESBL- and AmpC-producing Enterobacteriaceae.
Draft genome sequence data of a tigecycline-resistant Enterobacter cloacae ST93 clinical strain isolated from bloodstream infection.
The study reports the draft genome sequence of a tigecycline-resistant Enterobacter cloacae ST93 clinical isolate, TREC1, which harbors multiple antimicrobial resistance genes, including those encoding resistance to beta-lactams, aminoglycosides, fluoroquinolones, fosfomycin, macrolides, lincosamides, streptogramin B, phenicols, sulfonamides, trimethoprim, and tetracyclines. The isolate is resistant to all antibiotics tested except colistin.
Antimicrobial Resistance in ESBL-Producing E. coli Isolates from Companion Animals
The study identifies several novel beta-lactamase genes, including bla_SFO, bla_Cph, bla_VIM, bla_Act, bla_MIR, bla_MOX, and bla_PAO, along with commonly encountered genes like bla_CTX-M-15, bla_TEM-1B, and bla_OXA-1, in ESBL-producing E. coli isolates from companion animals.
False-Positive Carbapenem-Hydrolyzing Confirmatory Tests Due to ACT-28, a Chromosomally Encoded AmpC with Weak Carbapenemase Activity from Enterobacter kobei.
The study characterizes ACT-28, a chromosomally encoded AmpC beta-lactamase with weak carbapenemase activity from Enterobacter kobei, which can cause false-positive carbapenemase detection tests.
Transcriptome analysis of beta-lactamase genes in diarrheagenic Escherichia coli.
Genotypic antimicrobial resistance assays for use on E. coli isolates and stool specimens.
The study developed and validated 85 PCR assays to detect 79 AMR genes and mutations associated with resistance across 10 antimicrobial classes, focusing on E. coli. The assays showed high concordance with sequencing and phenotypic susceptibility testing, demonstrating their potential for AMR surveillance in E. coli isolates and direct stool specimens.
High Prevalence of Metallo-beta-lactamase-Producing Enterobacter cloacae From Three Tertiary Hospitals in China.
The study identified multiple metallo-beta-lactamase genes, including blaNDM-1, blaIMP-26, blaIMP-4, blaIMP-1, blaVIM-4, and blaKPC-2, as major contributors to carbapenem resistance in Enterobacter cloacae isolates from three hospitals in China.
Genomic characterization of an emerging bla(KPC-2) carrying Enterobacteriaceae clinical isolates in Thailand.
The study describes the first characterization of blaKPC-2 carrying Klebsiella pneumoniae, Escherichia coli, and Enterobacter asburiae isolates in Thailand, highlighting their resistance to carbapenems and other antibiotics.
Rapid MinION profiling of preterm microbiota and antimicrobial-resistant pathogens.
The study demonstrates the capability of MinION sequencing combined with NanoOK RT software to rapidly identify pathogens and their antimicrobial resistance gene profiles in preterm infants, enabling real-time diagnostics and resistance profiling.
In Vitro Pharmacodynamic Analyses Help Guide the Treatment of Multidrug-Resistant Enterococcus faecium and Carbapenem-Resistant Enterobacter cloacae Bacteremia in a Liver Transplant Patient.
The study identifies various AMR genes and mutations in Enterococcus faecium and Enterobacter hormaechei isolates from a liver transplant patient, highlighting their roles in resistance to multiple antibiotics.
Novel Cassette Assay To Quantify the Outer Membrane Permeability of Five β-Lactams Simultaneously in Carbapenem-Resistant Klebsiella pneumoniae and Enterobacter cloacae.
The study identifies various beta-lactamase genes, including bla KPC-2, bla TEM-1B, bla SHV-182, bla OXA-1, bla CTX-M-15, bla ACT-7, bla CTX-M-8, and bla OXA-9, which contribute to β-lactam resistance in carbapenem-resistant Klebsiella pneumoniae and Enterobacter cloacae isolates.
Clinical Evolution of AmpC-Mediated Ceftazidime-Avibactam and Cefiderocol Resistance in Enterobacter cloacae Complex Following Exposure to Cefepime.
Clinical Evolution of AmpC-Mediated Ceftazidime-Avibactam and Cefiderocol Resistance in Enterobacter cloacae Complex Following Exposure to Cefepime.
BKC-2, a New BKC Variant Detected in MCR-9.1-Producing Enterobacter hormaechei subsp. xiangfangensis.
The study identifies a new BKC variant, BKC-2, in MCR-9.1-producing Enterobacter hormaechei subsp. xiangfangensis, which confers resistance to carbapenems. It also characterizes the novel cephalosporinase ACT-84 and the colistin resistance gene mcr-9.1.
Colistin-resistant Enterobacter kobei carrying mcr-9.1 and bla(CTX-M-15) infecting a critically endangered franciscana dolphin (Pontoporia blainvillei), Brazil.
The study reports the emergence of the mcr-9.1 gene in a colistin-resistant Enterobacter kobei strain isolated from a critically endangered franciscana dolphin in Brazil, along with various other AMR genes.
High β-lactam resistance in Gram-negative bacteria associated with kennel cough and cat flu in Egypt.
The study identified various β-lactam resistance genes, including bla SHV, bla CTX-M, bla TEM, bla CMY, and bla ACT, as well as qnrS, which confer resistance to β-lactams and quinolones in Gram-negative bacteria associated with kennel cough and cat flu in Egypt.
Institutional outbreak involving multiple clades of IMP-producing Enterobacter cloacae complex sequence type 78 at a cancer center in Tokyo, Japan.
The study identified multiple clades of IMP-producing Enterobacter cloacae complex sequence type 78 (ST78) strains causing an institutional outbreak. These strains carried blaIMP-1 and blaIMP-11 genes on IncHI2 and IncL/M plasmids, along with various other resistance genes such as aac(6')-IIc, qnrB6, fosA, sul1, and tet(B).
Institutional outbreak involving multiple clades of IMP-producing Enterobacter cloacae complex sequence type 78 at a cancer center in Tokyo, Japan.
The study identified multiple clades of IMP-producing Enterobacter cloacae complex sequence type 78 (ST78) strains causing an institutional outbreak. These strains carried blaIMP-1 and blaIMP-11 genes on IncHI2 and IncL/M plasmids, along with various other resistance genes such as aac(6')-IIc, qnrB6, fosA, sul1, and tet(B).
Institutional outbreak involving multiple clades of IMP-producing Enterobacter cloacae complex sequence type 78 at a cancer center in Tokyo, Japan.
The study identified multiple clades of IMP-producing Enterobacter cloacae complex sequence type 78 (ST78) strains causing an institutional outbreak. These strains carried blaIMP-1 and blaIMP-11 genes on IncHI2 and IncL/M plasmids, along with various other resistance genes such as aac(6')-IIc, qnrB6, fosA, sul1, and tet(B).
Institutional outbreak involving multiple clades of IMP-producing Enterobacter cloacae complex sequence type 78 at a cancer center in Tokyo, Japan.
The study identified multiple clades of IMP-producing Enterobacter cloacae complex sequence type 78 (ST78) strains causing an institutional outbreak. These strains carried blaIMP-1 and blaIMP-11 genes on IncHI2 and IncL/M plasmids, along with various other resistance genes such as aac(6')-IIc, qnrB6, fosA, sul1, and tet(B).
Wide Distribution and Specific Resistance Pattern to Third-Generation Cephalosporins of Enterobacter cloacae Complex Members in Humans and in the Environment in Guadeloupe (French West Indies).
The study identifies several AMR genes and mutations associated with third-generation cephalosporin resistance in Enterobacter cloacae complex, including blaACT-16, blaACT-15, blaACT-7, qnrB1, qnrB19, qnrS2, fosA, oqxA, oqxB, mdfA, and mutations in ampD.
Wide Distribution and Specific Resistance Pattern to Third-Generation Cephalosporins of Enterobacter cloacae Complex Members in Humans and in the Environment in Guadeloupe (French West Indies).
The study identifies several AMR genes and mutations associated with third-generation cephalosporin resistance in Enterobacter cloacae complex, including blaACT-16, blaACT-15, blaACT-7, qnrB1, qnrB19, qnrS2, fosA, oqxA, oqxB, mdfA, and mutations in ampD.
Wide Distribution and Specific Resistance Pattern to Third-Generation Cephalosporins of Enterobacter cloacae Complex Members in Humans and in the Environment in Guadeloupe (French West Indies).
The study identifies several AMR genes and mutations associated with third-generation cephalosporin resistance in Enterobacter cloacae complex, including blaACT-16, blaACT-15, blaACT-7, qnrB1, qnrB19, qnrS2, fosA, oqxA, oqxB, mdfA, and mutations in ampD.
Wide Distribution and Specific Resistance Pattern to Third-Generation Cephalosporins of Enterobacter cloacae Complex Members in Humans and in the Environment in Guadeloupe (French West Indies).
The study identifies several AMR genes and mutations associated with third-generation cephalosporin resistance in Enterobacter cloacae complex, including blaACT-16, blaACT-15, blaACT-7, qnrB1, qnrB19, qnrS2, fosA, oqxA, oqxB, mdfA, and mutations in ampD.
Meropenem Versus Piperacillin-Tazobactam for Definitive Treatment of Bloodstream Infections Caused by AmpC β-Lactamase-Producing Enterobacter spp, Citrobacter freundii, Morganella morganii, Providencia spp, or Serratia marcescens: A Pilot Multicenter Randomized Controlled Trial (MERINO-2).
The study identified several AmpC β-lactamase genes, including bla CMY-2, bla CMY-101, bla CMY-51, bla ACT-17, bla ACT-12, bla ACT-15, bla ACT-16, bla ACT-2, bla ACT-27, bla ACT-38, bla ACT-40, bla ACT-43, bla ACT-49, bla ACT-55, bla CMH-3, bla CMH-1, bla DHA-17, bla DHA-20, bla DHA-12, bla DHA-16, bla DHA-18, bla MIR-18, bla MIR-19, and bla MIR-9, which confer resistance to piperacillin-tazobactam in various Enterobacterales species.
Meropenem Versus Piperacillin-Tazobactam for Definitive Treatment of Bloodstream Infections Caused by AmpC β-Lactamase-Producing Enterobacter spp, Citrobacter freundii, Morganella morganii, Providencia spp, or Serratia marcescens: A Pilot Multicenter Randomized Controlled Trial (MERINO-2).
The study identified several AmpC β-lactamase genes, including bla CMY-2, bla CMY-101, bla CMY-51, bla ACT-17, bla ACT-12, bla ACT-15, bla ACT-16, bla ACT-2, bla ACT-27, bla ACT-38, bla ACT-40, bla ACT-43, bla ACT-49, bla ACT-55, bla CMH-3, bla CMH-1, bla DHA-17, bla DHA-20, bla DHA-12, bla DHA-16, bla DHA-18, bla MIR-18, bla MIR-19, and bla MIR-9, which confer resistance to piperacillin-tazobactam in various Enterobacterales species.
Meropenem Versus Piperacillin-Tazobactam for Definitive Treatment of Bloodstream Infections Caused by AmpC β-Lactamase-Producing Enterobacter spp, Citrobacter freundii, Morganella morganii, Providencia spp, or Serratia marcescens: A Pilot Multicenter Randomized Controlled Trial (MERINO-2).
The study identified several AmpC β-lactamase genes, including bla CMY-2, bla CMY-101, bla CMY-51, bla ACT-17, bla ACT-12, bla ACT-15, bla ACT-16, bla ACT-2, bla ACT-27, bla ACT-38, bla ACT-40, bla ACT-43, bla ACT-49, bla ACT-55, bla CMH-3, bla CMH-1, bla DHA-17, bla DHA-20, bla DHA-12, bla DHA-16, bla DHA-18, bla MIR-18, bla MIR-19, and bla MIR-9, which confer resistance to piperacillin-tazobactam in various Enterobacterales species.
Meropenem Versus Piperacillin-Tazobactam for Definitive Treatment of Bloodstream Infections Caused by AmpC β-Lactamase-Producing Enterobacter spp, Citrobacter freundii, Morganella morganii, Providencia spp, or Serratia marcescens: A Pilot Multicenter Randomized Controlled Trial (MERINO-2).
The study identified several AmpC β-lactamase genes, including bla CMY-2, bla CMY-101, bla CMY-51, bla ACT-17, bla ACT-12, bla ACT-15, bla ACT-16, bla ACT-2, bla ACT-27, bla ACT-38, bla ACT-40, bla ACT-43, bla ACT-49, bla ACT-55, bla CMH-3, bla CMH-1, bla DHA-17, bla DHA-20, bla DHA-12, bla DHA-16, bla DHA-18, bla MIR-18, bla MIR-19, and bla MIR-9, which confer resistance to piperacillin-tazobactam in various Enterobacterales species.
Meropenem Versus Piperacillin-Tazobactam for Definitive Treatment of Bloodstream Infections Caused by AmpC β-Lactamase-Producing Enterobacter spp, Citrobacter freundii, Morganella morganii, Providencia spp, or Serratia marcescens: A Pilot Multicenter Randomized Controlled Trial (MERINO-2).
The study identified several AmpC β-lactamase genes, including bla CMY-2, bla CMY-101, bla CMY-51, bla ACT-17, bla ACT-12, bla ACT-15, bla ACT-16, bla ACT-2, bla ACT-27, bla ACT-38, bla ACT-40, bla ACT-43, bla ACT-49, bla ACT-55, bla CMH-3, bla CMH-1, bla DHA-17, bla DHA-20, bla DHA-12, bla DHA-16, bla DHA-18, bla MIR-18, bla MIR-19, and bla MIR-9, which confer resistance to piperacillin-tazobactam in various Enterobacterales species.
Meropenem Versus Piperacillin-Tazobactam for Definitive Treatment of Bloodstream Infections Caused by AmpC β-Lactamase-Producing Enterobacter spp, Citrobacter freundii, Morganella morganii, Providencia spp, or Serratia marcescens: A Pilot Multicenter Randomized Controlled Trial (MERINO-2).
The study identified several AmpC β-lactamase genes, including bla CMY-2, bla CMY-101, bla CMY-51, bla ACT-17, bla ACT-12, bla ACT-15, bla ACT-16, bla ACT-2, bla ACT-27, bla ACT-38, bla ACT-40, bla ACT-43, bla ACT-49, bla ACT-55, bla CMH-3, bla CMH-1, bla DHA-17, bla DHA-20, bla DHA-12, bla DHA-16, bla DHA-18, bla MIR-18, bla MIR-19, and bla MIR-9, which confer resistance to piperacillin-tazobactam in various Enterobacterales species.
Meropenem Versus Piperacillin-Tazobactam for Definitive Treatment of Bloodstream Infections Caused by AmpC β-Lactamase-Producing Enterobacter spp, Citrobacter freundii, Morganella morganii, Providencia spp, or Serratia marcescens: A Pilot Multicenter Randomized Controlled Trial (MERINO-2).
The study identified several AmpC β-lactamase genes, including bla CMY-2, bla CMY-101, bla CMY-51, bla ACT-17, bla ACT-12, bla ACT-15, bla ACT-16, bla ACT-2, bla ACT-27, bla ACT-38, bla ACT-40, bla ACT-43, bla ACT-49, bla ACT-55, bla CMH-3, bla CMH-1, bla DHA-17, bla DHA-20, bla DHA-12, bla DHA-16, bla DHA-18, bla MIR-18, bla MIR-19, and bla MIR-9, which confer resistance to piperacillin-tazobactam in various Enterobacterales species.
Meropenem Versus Piperacillin-Tazobactam for Definitive Treatment of Bloodstream Infections Caused by AmpC β-Lactamase-Producing Enterobacter spp, Citrobacter freundii, Morganella morganii, Providencia spp, or Serratia marcescens: A Pilot Multicenter Randomized Controlled Trial (MERINO-2).
The study identified several AmpC β-lactamase genes, including bla CMY-2, bla CMY-101, bla CMY-51, bla ACT-17, bla ACT-12, bla ACT-15, bla ACT-16, bla ACT-2, bla ACT-27, bla ACT-38, bla ACT-40, bla ACT-43, bla ACT-49, bla ACT-55, bla CMH-3, bla CMH-1, bla DHA-17, bla DHA-20, bla DHA-12, bla DHA-16, bla DHA-18, bla MIR-18, bla MIR-19, and bla MIR-9, which confer resistance to piperacillin-tazobactam in various Enterobacterales species.
Meropenem Versus Piperacillin-Tazobactam for Definitive Treatment of Bloodstream Infections Caused by AmpC β-Lactamase-Producing Enterobacter spp, Citrobacter freundii, Morganella morganii, Providencia spp, or Serratia marcescens: A Pilot Multicenter Randomized Controlled Trial (MERINO-2).
The study identified several AmpC β-lactamase genes, including bla CMY-2, bla CMY-101, bla CMY-51, bla ACT-17, bla ACT-12, bla ACT-15, bla ACT-16, bla ACT-2, bla ACT-27, bla ACT-38, bla ACT-40, bla ACT-43, bla ACT-49, bla ACT-55, bla CMH-3, bla CMH-1, bla DHA-17, bla DHA-20, bla DHA-12, bla DHA-16, bla DHA-18, bla MIR-18, bla MIR-19, and bla MIR-9, which confer resistance to piperacillin-tazobactam in various Enterobacterales species.
Meropenem Versus Piperacillin-Tazobactam for Definitive Treatment of Bloodstream Infections Caused by AmpC β-Lactamase-Producing Enterobacter spp, Citrobacter freundii, Morganella morganii, Providencia spp, or Serratia marcescens: A Pilot Multicenter Randomized Controlled Trial (MERINO-2).
The study identified several AmpC β-lactamase genes, including bla CMY-2, bla CMY-101, bla CMY-51, bla ACT-17, bla ACT-12, bla ACT-15, bla ACT-16, bla ACT-2, bla ACT-27, bla ACT-38, bla ACT-40, bla ACT-43, bla ACT-49, bla ACT-55, bla CMH-3, bla CMH-1, bla DHA-17, bla DHA-20, bla DHA-12, bla DHA-16, bla DHA-18, bla MIR-18, bla MIR-19, and bla MIR-9, which confer resistance to piperacillin-tazobactam in various Enterobacterales species.
Meropenem Versus Piperacillin-Tazobactam for Definitive Treatment of Bloodstream Infections Caused by AmpC β-Lactamase-Producing Enterobacter spp, Citrobacter freundii, Morganella morganii, Providencia spp, or Serratia marcescens: A Pilot Multicenter Randomized Controlled Trial (MERINO-2).
The study identified several AmpC β-lactamase genes, including bla CMY-2, bla CMY-101, bla CMY-51, bla ACT-17, bla ACT-12, bla ACT-15, bla ACT-16, bla ACT-2, bla ACT-27, bla ACT-38, bla ACT-40, bla ACT-43, bla ACT-49, bla ACT-55, bla CMH-3, bla CMH-1, bla DHA-17, bla DHA-20, bla DHA-12, bla DHA-16, bla DHA-18, bla MIR-18, bla MIR-19, and bla MIR-9, which confer resistance to piperacillin-tazobactam in various Enterobacterales species.
The Epidemiology, Virulence and Antimicrobial Resistance of Invasive Klebsiella pneumoniae at a Children's Medical Center in Eastern China.
The study identified multiple beta-lactam resistance genes, including bla SHV-11, bla FOX-1, bla ACT-1, bla CTX-M-14, bla TEM-1, bla VIM-1, bla NDM-1, bla KPC-2, and bla OXA-1, in invasive Klebsiella pneumoniae isolates. Additionally, hypervirulence genes such as iroB, p rmpA, mrkD, wabG, Uge, fimH, and ycfM were prevalent.
Genetic Characterization of Antibiotic Resistant Enterobacteriaceae Isolates From Bovine Animals and the Environment in Nigeria.
The study characterizes antibiotic resistance genes in Enterobacteriaceae isolates from bovine animals and the environment in Nigeria, identifying several beta-lactamase, aminoglycoside modifying enzymes, qnr, sulfonamide, tetracycline, and trimethoprim resistance genes, highlighting the presence of multidrug-resistant strains.
Genetic Characterization of Antibiotic Resistant Enterobacteriaceae Isolates From Bovine Animals and the Environment in Nigeria.
The study characterizes antibiotic resistance genes in Enterobacteriaceae isolates from bovine animals and the environment in Nigeria, identifying several beta-lactamase, aminoglycoside modifying enzymes, qnr, sulfonamide, tetracycline, and trimethoprim resistance genes, highlighting the presence of multidrug-resistant strains.
Whole Genome Sequence Analysis of Multidrug Resistant Escherichia coli and Klebsiella pneumoniae Strains in Kuwait.
The study identified multiple AMR genes in multidrug-resistant E. coli and K. pneumoniae isolates from Kuwait, including beta-lactamases (blaKPC-2, blaCTX-M-15, blaOXA-1, blaCMY-4, blaTEM), aminoglycoside-modifying enzymes (aac(3)-IIa, aph(6)-Id, aadA5), sulfonamide resistance genes (sul1, sul2), quinolone resistance genes (gyrA_D87N, qnrB1), and others. Colistin resistance was linked to the pmrB_R256G mutation.
Surveillance of Enterobacter cloacae complex colonization and comparative analysis of different typing methods on a neonatal intensive care unit in Germany.
The study identified various beta-lactamase genes (blaACT-15, blaACT-14, blaACT-7, blaCMH-3) and the fosA gene associated with third-generation cephalosporin resistance in Enterobacter cloacae complex isolates.
Surveillance of Enterobacter cloacae complex colonization and comparative analysis of different typing methods on a neonatal intensive care unit in Germany.
The study identified various beta-lactamase genes (blaACT-15, blaACT-14, blaACT-7, blaCMH-3) and the fosA gene associated with third-generation cephalosporin resistance in Enterobacter cloacae complex isolates.
Surveillance of Enterobacter cloacae complex colonization and comparative analysis of different typing methods on a neonatal intensive care unit in Germany.
The study identified various beta-lactamase genes (blaACT-15, blaACT-14, blaACT-7, blaCMH-3) and the fosA gene associated with third-generation cephalosporin resistance in Enterobacter cloacae complex isolates.
Molecular characterization of extended spectrum cephalosporin resistant Escherichia coli isolated from livestock and in-contact humans in Southeast Nigeria.
The study identified four variants of bla CTX-M (CTX-M-15, CTX-M-55, CTX-M-64, and CTX-M-65) in extended-spectrum cephalosporin-resistant Escherichia coli from livestock and in-contact humans in Southeast Nigeria. Other AMR genes such as bla TEM-1b, aac 3-IId, qnr S1, and sul 2 were also characterized.
Dynamics of Microbial Community and Potential Microbial Pollutants in Shopping Malls.
The study identified several antimicrobial resistance genes, including CRP, ACT-1, baeR, acrA, H-NS, and oqxB, in Enterobacteriaceae isolates from shopping mall surfaces, highlighting the presence of multidrug efflux systems and antibiotic target alterations as key resistance mechanisms.
Characterization of cephalosporin and fluoroquinolone resistant Enterobacterales from Irish farm waste by whole genome sequencing.
The study identified several beta-lactamase genes (bla CTX-M-14, bla CTX-M-15, bla CMY-2, bla SHV-12, and bla ACT-14) and a quinolone resistance gene (qnr S1) associated with cephalosporin and fluoroquinolone resistance in Enterobacterales from Irish farm waste. Additionally, mutations in gyr A, par C, and par E were linked to fluoroquinolone resistance.
Performance of Phenotypic Tests to Detect beta-lactamases in a Population of beta-lactamase Coproducing Enterobacteriaceae Isolates.
The study identified various beta-lactamase genes including CTX-M, CMY, DHA, ACT, NDM, and OXA-48-like in Enterobacteriaceae isolates. These genes were associated with resistance to multiple β-lactam antibiotics. The performance of phenotypic tests for detecting these resistance mechanisms was evaluated.
ACT-107, a novel variant of AmpC beta-lactamase from Enterobacter huaxiensis isolated from Neotropical leaf frog (Phyllomedusa distincta) inhabiting the Brazilian Atlantic Forest.
The study reports the identification of a novel AmpC beta-lactamase variant, ACT-107, from Enterobacter huaxiensis isolated from a Neotropical leaf frog, which confers resistance to various β-lactam antibiotics.
Plasmid-mediated colistin resistance among human clinical Enterobacterales isolates: national surveillance in the Czech Republic.
The study identified mcr-1, mcr-4, and mcr-9 genes in colistin-resistant Enterobacterales isolates from the Czech Republic, highlighting their association with plasmid-mediated resistance and multidrug resistance features.
Plasmid-mediated colistin resistance among human clinical Enterobacterales isolates: national surveillance in the Czech Republic.
The study identified mcr-1, mcr-4, and mcr-9 genes in colistin-resistant Enterobacterales isolates from the Czech Republic, highlighting their association with plasmid-mediated resistance and multidrug resistance features.
Plasmid-mediated colistin resistance among human clinical Enterobacterales isolates: national surveillance in the Czech Republic.
The study identified mcr-1, mcr-4, and mcr-9 genes in colistin-resistant Enterobacterales isolates from the Czech Republic, highlighting their association with plasmid-mediated resistance and multidrug resistance features.
In Vitro Activity of Cefiderocol against Clinical Gram-Negative Isolates Originating from Germany in 2016/17.
The study identified several beta-lactamase genes, including bla NDM-1, bla SHV-12, bla OXA-396, bla ACT-type, and bla CMH-3, which contribute to cefiderocol resistance in clinical Gram-negative isolates from Germany.
Impact of acquired broad-spectrum beta-lactamases on susceptibility to oral penems/carbapenems (tebipenem, sulopenem, and faropenem) alone or in combination with avibactam and taniborbactam beta-lactamase inhibitors in Escherichia coli.
The study evaluates the impact of various beta-lactamases on the susceptibility of Escherichia coli to oral penems/carbapenems (tebipenem, sulopenem, and faropenem) and their combinations with beta-lactamase inhibitors avibactam and taniborbactam.
Impact of acquired broad-spectrum beta-lactamases on susceptibility to oral penems/carbapenems (tebipenem, sulopenem, and faropenem) alone or in combination with avibactam and taniborbactam beta-lactamase inhibitors in Escherichia coli.
The study evaluates the impact of various beta-lactamases on the susceptibility of Escherichia coli to oral penems/carbapenems (tebipenem, sulopenem, and faropenem) and their combinations with beta-lactamase inhibitors avibactam and taniborbactam.
Characterization of Carbapenemase- and ESBL-Producing Gram-Negative Bacilli Isolated from Patients with Urinary Tract and Bloodstream Infections.
The study identified multiple carbapenemase and ESBL genes, including bla KPC-2, bla KPC-3, bla NDM, bla CTX-M-15, bla CTX-M-27, bla CTX-M-14, bla SHV-187, bla SHV-12, bla OXA-181, and others, highlighting the diversity of beta-lactam resistance mechanisms in Gram-negative bacteria from urinary tract and bloodstream infections.
Predicting Human Risk with Multidrug Resistant Enterobacter hormaechei MS2 having MCR 9 Gene Isolated from the Feces of Healthy Broiler Through Whole-Genome Sequence-Based Analysis.
The study identifies the MCR-9, FosA2, and ACT-69 genes in Enterobacter hormaechei MS2, highlighting its multidrug resistance and zoonotic potential.
High Diversity but Monodominance of Multidrug-Resistant Bacteria in Immunocompromised Pediatric Patients with Acute Lymphoblastic Leukemia Developing GVHD Are Not Associated with Changes in Gut Mycobiome.
The study identifies multiple multidrug-resistant bacteria, including Enterococcus faecium and Klebsiella pneumoniae, carrying various resistance genes such as msr(C), erm(T), aac(6')-li, dfrG, ant(6)-la, aph(3")-Ib, sul2, and aph(6)-ld, which confer resistance to multiple antibiotics.
Shotgun Metagenomics-Guided Prediction Reveals the Metal Tolerance and Antibiotic Resistance of Microbes in Poly-Extreme Environments in the Danakil Depression, Afar Region.
The study identified numerous antibiotic resistance genes (ARGs) and metal resistance genes (MRGs) in the metagenomes of Lake Afdera and the Assale salt plain in the Danakil Depression. Key ARGs included beta-lactamases (ACC-1, OXA-58, OXA-363, OXA-212, NDM-17, OXA-134, ACT-29, LRA-19), efflux pumps (emrB, abeM, abeS, mgrA, adeJ, MexC, adeL, adeH), sulfonamide resistance genes (sul1, sul2), tetracycline resistance genes (tet39, tetX, tetK), and others. MRGs included copper resistance genes (copC, copD), cadmium resistance gene (cadD), mercury resistance gene (merA), chromate resistance genes (chrB, chrA), nickel-cobalt-cadmium resistance genes (nccA, nccB), cobalt-zinc-cadmium resistance gene (czcD), arsenic resistance gene (arsO), lead resistance gene (pbrA), and mercury resistance genes (merB, merR, MIR).
Prevalence, antibiotic resistance and molecular characterization of Staphylococcus aureus in ready-to-eat fruits and vegetables in Shanghai, China.
The study identified several antibiotic resistance genes in Staphylococcus aureus isolates from ready-to-eat fruits and vegetables in Shanghai, China, including genes conferring resistance to beta-lactams, fluoroquinolones, aminoglycosides, lincosamides, and fosfomycin.
Genomic investigation unveils high-risk ESBL producing Enterobacteriaceae within a rural environmental water body.
The study identifies several AMR genes and mutations in ESBL-producing Enterobacteriaceae isolated from a rural environmental water body in India, highlighting the presence of multidrug-resistant strains with genes such as bla VEB-6, bla SHV-12, bla NDM-1, bla CTX-M, and mcr-9, along with mutations in ompK 36 and gyrA.
Genomic, functional, and metabolic enhancements in multidrug-resistant Enterobacter bugandensis facilitating its persistence and succession in the International Space Station.
The study identifies multiple antibiotic resistance genes in multidrug-resistant Enterobacter bugandensis strains isolated from the International Space Station, highlighting their potential to persist and succeed in extreme environments.
Monitoring Changes in the Antimicrobial-Resistance Gene Set (ARG) of Raw Milk and Dairy Products in a Cattle Farm, from Production to Consumption.
The study identified 112 antibiotic-resistance genes in raw milk and dairy products, with a significant increase in resistant genes in aged cheese compared to raw milk. Key genes included OXA-662 and OXA-309, which confer resistance to beta-lactam antibiotics, and several efflux pump genes like abaQ, emrA, and acrAB-tolC, which contribute to fluoroquinolone resistance. The findings highlight the dynamic changes in the resistome during food processing and the potential public health risks associated with the spread of antibiotic resistance genes through raw dairy products.
Whole-Genome Analysis of Extensively Drug-Resistant Enterobacter hormaechei Isolated from a Patient with Non-Hodgkin's Lymphoma.
The study identifies an extensively drug-resistant Enterobacter hormaechei ST90 clone carrying multiple resistance genes, including bla CTX-M-15, bla GES-2, bla TEM-1A, bla OXA-1, bla NDM-1, and bla ACT-15, along with genes encoding resistance to aminoglycosides, quinolones, sulfonamides, chloramphenicol, fosfomycin, and other antibiotics.
Relative inhibitory activities of newly developed diazabicyclooctanes, boronic acid derivatives, and penicillin-based sulfone beta-lactamase inhibitors against broad-spectrum AmpC beta-lactamases.
The study evaluates the inhibitory activities of various beta-lactamase inhibitors against a wide range of AmpC beta-lactamases, identifying the effectiveness of certain inhibitors like durlobactam and zidebactam in reducing the MIC values of β-lactam antibiotics against AmpC-producing strains.
Relative inhibitory activities of newly developed diazabicyclooctanes, boronic acid derivatives, and penicillin-based sulfone beta-lactamase inhibitors against broad-spectrum AmpC beta-lactamases.
The study evaluates the inhibitory activities of various beta-lactamase inhibitors against a wide range of AmpC beta-lactamases, identifying the effectiveness of certain inhibitors like durlobactam and zidebactam in reducing the MIC values of β-lactam antibiotics against AmpC-producing strains.
Characterizing Methicillin-Resistant Staphylococcus spp. and Extended-Spectrum Cephalosporin-Resistant Escherichia coli in Cattle.
The study identified several AMR genes in E. coli and MRSA isolates from cattle in Austria, including bla CTX-M-1/15, bla CTX-M-9, bla TEM, tet (A), tet (B), dfrA1, dfrA5, dfrA14, dfrA17, sul2, sul3, aadA1, aadA2, floR, cmlA, aphA, and bla ACT. Additionally, the MRSA isolate carried the mecA gene, indicating methicillin resistance.
First report on comprehensive genomic analysis of a multidrug-resistant Enterobacter asburiae isolated from diabetic foot infection from Bangladesh.
The study identifies multiple antimicrobial resistance genes, including blaACT-2, fosA2, vanA, vanB, and vanG, in a multidrug-resistant Enterobacter asburiae isolate from a diabetic foot infection in Bangladesh.
Phenotypic and Genomic Characterization of ESBL- and AmpC-β-Lactamase-Producing Enterobacterales Isolates from Imported Healthy Reptiles.
The study identified multiple ESBL and AmpC β-lactamase genes, including bla CTX-M-15, bla CTX-M-55, bla CTX-M-3, bla CTX-M-27, bla CTX-M-65, bla SHV-12, bla SHV-42, bla DHA-1, bla CMY-2, bla CMY-3, bla CMY-46, bla CMY-101, bla ACT-16, bla CMH-like, and bla MIR-9, along with other AMR genes such as mcr-1, qnrS1, aac(6')-Ib-cr5, and various tetracycline, aminoglycoside, sulfonamide, chloramphenicol, macrolide, lincosamide, and rifampicin resistance genes in Enterobacterales isolates from imported healthy reptiles.
Genomic analysis of Enterobacter cloacae complex from Southern Thailand reveals insights into multidrug resistance genotypes and genetic diversity.
The study identified multiple antimicrobial resistance genes in Enterobacter cloacae complex isolates from Southern Thailand, including beta-lactamases, aminoglycoside modifying enzymes, tetracycline resistance genes, and efflux pumps. Notably, the mcr-9 gene was found to confer colistin resistance.
Antimicrobial Resistance in Nigeria: A Comprehensive Review of Environmental, Food, and Clinical Impacts
The study identifies several AMR genes, including bla CTX-M-15, floR, and various tetracycline and sulfonamide resistance genes, highlighting the spread of multidrug-resistant bacteria in Nigeria's environment, food supply chain, and clinical settings.
Rapid whole genome sequencing for AMR surveillance in low- and middle-income countries: Oxford Nanopore Technology reveals multidrug-resistant Enterobacter cloacae complex from dairy farms in Sri Lanka.
The study identified multiple AMR genes in multidrug-resistant Enterobacter isolates from dairy farms in Sri Lanka, including blaCMH-1, blaACT-25, blaCTX-M-15, blaOXA-1, blaTEM-1, blaNDM-4, and blaNDM-15, highlighting the presence of carbapenem-resistant Enterobacterales and the need for improved AMR surveillance in low-resource settings.
Broadly reactive monoclonal antibodies against beta-lactamases for immunodetection of bacterial resistance to antibiotics.
The study describes broadly reactive monoclonal antibodies (MAbs) against AmpC beta-lactamases, which are key enzymes in bacterial resistance to beta-lactam antibiotics. These MAbs recognize a conserved epitope of 11 amino acids and show cross-reactivity with various AmpC beta-lactamases, including DHA-1, CMY-34, ACT-14, PDC-195, and ADC-144.
Metagenomic analysis after selective culture enrichment of hospital and community wastewater enhances antimicrobial resistance gene detection.
The study identifies various beta-lactamase genes such as bla CTX-M, bla KPC, bla NDM, and bla VIM, along with other resistance genes like erm(TR), lsa, efrA, efrB, and optrA, which were detected through selective culture enrichment of wastewater samples.
Nanopore Sequencing-Driven Mapping of Antimicrobial Resistance Genes in Selected Escherichia coli Isolates from Pigs and Poultry Layers in Nigeria.
The study identified 95 antimicrobial resistance genes in 10 E. coli isolates from pigs and poultry in Nigeria, including genes such as qnrS1, qnrS10, qnrS15, kdpE, cmlA1, MIR-14, sul3, dfrA12, blaEc15, blaACT58, and blaEc18, which confer resistance to various antibiotics.
Whole-genome sequencing reveals Enterobacter hormaechei as a key bloodstream pathogen in six tertiary care hospitals in southwestern Nigeria.
The study identifies several AMR genes in Enterobacter hormaechei and Enterobacter cloacae, including bla ACT-45, bla CTX-M-15, bla NDM-1, dfrA14, mcr10.1, aac(3)-Ile, aph(3′)-Ib, qnrB1, sul1, sul2, tet(A), catA1, and mphA, highlighting the prevalence of multidrug resistance in these species.
One-step degradation of 4 classes of β-lactam using beta-lactamase enzyme cocktail.
The study identified and characterized four beta-lactamases (CTX-33, VIM-1, ACT-3, and OXA-65) with broad substrate spectra for degrading β-lactam antibiotics. An optimized enzyme cocktail (CTX-33:VIM-1 at 4:1 ratio) effectively degraded all four classes of β-lactam antibiotics (penicillin, cephalosporin, carbapenem, and monobactam) in various water samples.
No evidence of multidrug-resistant Enterobacterales transmission between healthy companion animals and pet owners in the greater Atlanta area: a pilot study.
The study identified several AMR genes and mutations in E. coli isolates from both humans and pets, including blaCMY-2, blaCTX-M-15, blaTEM-1B, and mutations in gyrA and parC. These findings highlight the presence of multidrug-resistant Enterobacterales in healthy individuals and their companion animals.
No evidence of multidrug-resistant Enterobacterales transmission between healthy companion animals and pet owners in the greater Atlanta area: a pilot study.
The study identified several AMR genes and mutations in E. coli isolates from both humans and pets, including blaCMY-2, blaCTX-M-15, blaTEM-1B, and mutations in gyrA and parC. These findings highlight the presence of multidrug-resistant Enterobacterales in healthy individuals and their companion animals.
Ultrasound-Assisted Extraction: Unlocking the Antibacterial Potential of Coptis chinensis Franch. Against ESBL-Producing Enterobacterales.
The study identifies multiple beta-lactamase resistance genes in ESBL-PE strains, including blaCTX-M-14, blaCTX-M-1, blaCTX-M-3, blaCTX-M-15, blaCTX-M-65, blaSHV, blaTEM, blaEC, blaACC, blaCMY, blaACT, blaDHA, and efflux pump genes such as acrF, emrD, mdtM, silA, kdeA, oqxA, oqxB, arsB, oqxA10, oqxB5, oqxB19, arsA, and hugA, which contribute to multidrug resistance in these isolates.
Precise species identification and whole-genome sequencing analysis of Enterobacter cloacae complex causing bloodstream infections in China.
The study identified various AMR genes in Enterobacter cloacae complex (ECC) isolates, including bla ACT, bla NDM, and mcr-10, which confer resistance to beta-lactams, carbapenems, and polymyxins, respectively. It also found that E. roggenkampii was the most common species among carbapenem-resistant isolates and showed high resistance to both carbapenems and colistin.
Precise species identification and whole-genome sequencing analysis of Enterobacter cloacae complex causing bloodstream infections in China.
The study identified various AMR genes in Enterobacter cloacae complex (ECC) isolates, including bla ACT, bla NDM, and mcr-10, which confer resistance to beta-lactams, carbapenems, and polymyxins, respectively. It also found that E. roggenkampii was the most common species among carbapenem-resistant isolates and showed high resistance to both carbapenems and colistin.
Precise species identification and whole-genome sequencing analysis of Enterobacter cloacae complex causing bloodstream infections in China.
The study identified various AMR genes in Enterobacter cloacae complex (ECC) isolates, including bla ACT, bla NDM, and mcr-10, which confer resistance to beta-lactams, carbapenems, and polymyxins, respectively. It also found that E. roggenkampii was the most common species among carbapenem-resistant isolates and showed high resistance to both carbapenems and colistin.
Precise species identification and whole-genome sequencing analysis of Enterobacter cloacae complex causing bloodstream infections in China.
The study identified various AMR genes in Enterobacter cloacae complex (ECC) isolates, including bla ACT, bla NDM, and mcr-10, which confer resistance to beta-lactams, carbapenems, and polymyxins, respectively. It also found that E. roggenkampii was the most common species among carbapenem-resistant isolates and showed high resistance to both carbapenems and colistin.
Precise species identification and whole-genome sequencing analysis of Enterobacter cloacae complex causing bloodstream infections in China.
The study identified various AMR genes in Enterobacter cloacae complex (ECC) isolates, including bla ACT, bla NDM, and mcr-10, which confer resistance to beta-lactams, carbapenems, and polymyxins, respectively. It also found that E. roggenkampii was the most common species among carbapenem-resistant isolates and showed high resistance to both carbapenems and colistin.
Precise species identification and whole-genome sequencing analysis of Enterobacter cloacae complex causing bloodstream infections in China.
The study identified various AMR genes in Enterobacter cloacae complex (ECC) isolates, including bla ACT, bla NDM, and mcr-10, which confer resistance to beta-lactams, carbapenems, and polymyxins, respectively. It also found that E. roggenkampii was the most common species among carbapenem-resistant isolates and showed high resistance to both carbapenems and colistin.
Precise species identification and whole-genome sequencing analysis of Enterobacter cloacae complex causing bloodstream infections in China.
The study identified various AMR genes in Enterobacter cloacae complex (ECC) isolates, including bla ACT, bla NDM, and mcr-10, which confer resistance to beta-lactams, carbapenems, and polymyxins, respectively. It also found that E. roggenkampii was the most common species among carbapenem-resistant isolates and showed high resistance to both carbapenems and colistin.
Molecular evolution of a class C beta-lactamase extending its substrate specificity.
Molecular evolution of a class C beta-lactamase extending its substrate specificity.
Imipenem resistance in Klebsiella pneumoniae is associated with the combination of ACT-1, a plasmid-mediated AmpC beta-lactamase, and the foss of an outer membrane protein.
The study identifies ACT-1, a plasmid-mediated AmpC beta-lactamase, as a key factor in imipenem resistance in Klebsiella pneumoniae, along with the loss of a major outer membrane protein.
Imipenem resistance in Klebsiella pneumoniae is associated with the combination of ACT-1, a plasmid-mediated AmpC beta-lactamase, and the foss of an outer membrane protein.
Imipenem resistance in Klebsiella pneumoniae is associated with the combination of ACT-1, a plasmid-mediated AmpC beta-lactamase, and the foss of an outer membrane protein.
Imipenem resistance in Klebsiella pneumoniae is associated with the combination of ACT-1, a plasmid-mediated AmpC beta-lactamase, and the foss of an outer membrane protein.
Imipenem resistance in Klebsiella pneumoniae is associated with the combination of ACT-1, a plasmid-mediated AmpC beta-lactamase, and the foss of an outer membrane protein.
No comments yet. Be the first to comment!