Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
extended-spectrum class C beta-lactamase ADC-10
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| blaADC-10 | Card DatabaseReference Gene CatalogReslit | 3 | CEPHALOSPORIN, beta lactams | Acinetobacter baumannii +1 | Iraq|Afghanistan | 2022 | DQ883640.1 | ABI18382.1 |
| blaADC-100 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | KX599382.1 | ANW47141.1 |
| blaADC-101 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | KX599374.1 | ANW47133.1 |
| blaADC-102 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | KX599389.1 | ANW47148.1 |
| blaADC-103 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | KX609236.1 | ANW69905.1 |
| blaADC-104 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | KX609237.1 | ANW69906.1 |
| blaADC-105 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | KX609238.1 | ANW69907.1 |
| blaADC-106 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | KX609240.1 | ANW69909.1 |
| blaADC-107 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | KX609243.1 | ANW69912.1 |
| blaADC-110 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | EF433777.1 | ABO38124.1 |
| blaADC-114 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii MDR_MMC4 | - | - | AZNQ01000099.1 | ETY67158.1 |
| blaADC-119 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii NIPH 1669 | - | - | APOQ01000006.1 | ENU51112.1 |
| blaADC-120 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii NIPH 190 | - | - | APPL01000015.1 | ENV26641.1 |
| blaADC-121 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii NIPH 201 | - | - | APQV01000007.1 | ENW36647.1 |
| blaADC-122 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii NIPH 329 | - | - | APQY01000003.1 | ENW46489.1 |
| blaADC-123 | Card DatabaseReference Gene CatalogReslit | 4 | CEPHALOSPORIN, carbapenems | Acinetobacter baumannii NIPH 60 +1 | United States|Minnesota | 2025 | APPM01000011.1 | ENV30802.1 |
| blaADC-125 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii NIPH 67 | - | - | APRA01000004.1 | ENW51227.1 |
| blaADC-127 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter calcoaceticus DSM 30006 = CIP 81.8 | - | - | APQI01000003.1 | ENW00696.1 |
| blaADC-128 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter calcoaceticus NIPH 13 | - | - | APOE01000009.1 | ENU07956.1 |
| blaADC-129 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter calcoaceticus ANC 3680 | - | - | APQH01000006.1 | ENV92309.1 |
| blaADC-130 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter nosocomialis NIPH 386 | - | - | APPP01000013.1 | ENV41121.1 |
| blaADC-131 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter nosocomialis NIPH 2119 | - | - | APOP01000002.1 | ENU48760.1 |
| blaADC-132 | Card DatabaseReference Gene CatalogReslit | 4 | CEPHALOSPORIN, cephalosporins | Acinetobacter pittii ANC 3678 +1 | Europe|Japan|Hong Kong|Mexico|US|China|Spain | 2025 | APQN01000012.1 | ENW11417.1 |
| blaADC-133 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter seifertii | - | - | APOO01000021.1 | ENU43147.1 |
| blaADC-134 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter sp. NIPH 542 | - | - | APSC01000009.1 | ENX43770.1 |
| blaADC-135 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter sp. NIPH 817 | - | - | APPF01000018.1 | ENV03983.1 |
| blaADC-136 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter calcoaceticus ANC 3811 | - | - | APQJ01000005.1 | EOQ64883.1 |
| blaADC-137 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter pittii ANC 4050 | - | - | APQM01000001.1 | EOQ71234.1 |
| blaADC-138 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter lactucae | - | - | APQO01000006.1 | EOQ73533.1 |
| blaADC-139 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii 1406589 | - | - | JFYI01000005.1 | EXS60093.1 |
| blaADC-140 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii 16553_10 | - | - | JHPF01000005.1 | EYS55294.1 |
| blaADC-141 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii 58452 | - | - | JEZV01000049.1 | EXD64655.1 |
| blaADC-143 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii TYTH-6 | - | - | AGSU01000096.1 | WP_033502167.1 |
| blaADC-145 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JWWE03000102.1 | KHY08585.1 |
| blaADC-146 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JWSI03000106.1 | KHV30477.1 |
| blaADC-147 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JZCF02000002.1 | OLU89926.1 |
| blaADC-148 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter nosocomialis | - | - | CP010368.1 | AJB47604.1 |
| blaADC-150 | Card DatabaseReference Gene CatalogReslit | 4 | CEPHALOSPORIN, cephalosporins | Acinetobacter pittii | Europe|Japan|Hong Kong|Mexico|US|China|Spain | 2025 | KR153290.1 | AKT73351.1 |
| blaADC-151 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter pittii | - | - | CP015145.1 | AMX20227.1 |
| blaADC-152 | Card DatabaseReference Gene CatalogReslit | 5 | CEPHALOSPORIN, cephalosporins | Acinetobacter baumannii | Switzerland|France|Bahrain | 2021, 2022 | KY674540.1 | AQV05407.1 |
| blaADC-154 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MF152948.1 | ART46239.1 |
| blaADC-155 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MF164462.1 | ARX71325.1 |
| blaADC-156 | Card DatabaseReference Gene CatalogReslit | 4 | CEPHALOSPORIN, cephalosporins | Acinetobacter baumannii | - | 2021 | MF164463.1 | ARX71326.1 |
| blaADC-157 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MF164464.1 | ARX71327.1 |
| blaADC-158 | Card DatabaseReference Gene CatalogReslit | 5 | CEPHALOSPORIN, ceftazidime +3 | Acinetobacter baumannii | Peninsular Malaysia|Malaysia | 2023, 2025 | MG229640.1 | ATP60650.1 |
| blaADC-159 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MG229642.1 | ATP60652.1 |
| blaADC-160 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MG229643.1 | ATP60653.1 |
| blaADC-162 | Card DatabaseReference Gene CatalogReslit | 6 | CEPHALOSPORIN, cefotaxime +2 | Acinetobacter baumannii +1 | China, Europe|United States | 2019, 2021 | MG452939.1 | ATW66974.1 |
| blaADC-163 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MG601728.1 | AUD40657.1 |
| blaADC-164 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MG601731.1 | AUD40660.1 |
| blaADC-165 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MG601733.1 | AUD40662.1 |
| blaADC-166 | Card DatabaseReference Gene CatalogReslit | 4 | CEPHALOSPORIN, ampicillin +3 | Acinetobacter baumannii | Japan | 2020 | MG601734.1 | AUD40663.1 |
| blaADC-167 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MG601735.1 | AUD40664.1 |
| blaADC-168 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MG601736.1 | AUD40665.1 |
| blaADC-169 | Card DatabaseReference Gene CatalogReslit | 4 | CEPHALOSPORIN, cephalosporins | Acinetobacter baumannii | Peninsular Malaysia|Malaysia | 2025 | MG702533.1 | AUG98343.1 |
| blaADC-170 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MF990804.1 | AUI41018.1 |
| blaADC-171 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii 24860_7 | - | - | JFDD01000056.1 | EXG42507.1 |
| blaADC-172 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii 653020 | - | - | JEZU01000044.1 | EXD57031.1 |
| blaADC-173 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii 836190 | - | - | JFFA01000050.1 | EXI26748.1 |
| blaADC-174 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MH594296.1 | AXC08546.1 |
| blaADC-175 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MH594297.1 | AXC08547.1 |
| blaADC-176 | Card DatabaseReference Gene CatalogReslit | 4 | CEPHALOSPORIN, cephalosporins | Acinetobacter baumannii | - | 2021 | MH594298.1 | AXC08548.1 |
| blaADC-178 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MH594300.1 | AXC08550.1 |
| blaADC-179 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MH594301.1 | AXC08551.1 |
| blaADC-180 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MH594302.1 | AXC08552.1 |
| blaADC-181 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MK248721.1 | AZK35803.1 |
| blaADC-182 | Card DatabaseReference Gene CatalogReslit | 3 | CEPHALOSPORIN, cephalosporins | Acinetobacter baumannii | - | 2021 | MK248722.1 | AZK35804.1 |
| blaADC-183 | Card DatabaseReference Gene CatalogReslit | 3 | CEPHALOSPORIN, ceftazidime | Acinetobacter baumannii | Brazil | 2025 | MK248723.1 | AZK35805.1 |
| blaADC-184 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MK482710.1 | QBC36170.1 |
| blaADC-185 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MK482711.1 | QBC36171.1 |
| blaADC-186 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MK482712.1 | QBC36172.1 |
| blaADC-187 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MK482713.1 | QBC36173.1 |
| blaADC-188 | Card DatabaseReference Gene CatalogReslit | 4 | CEPHALOSPORIN, cephalosporins | Acinetobacter baumannii | Switzerland|France|Bahrain | 2022 | MK482715.1 | QBC36175.1 |
| blaADC-189 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MK482716.1 | QBC36176.1 |
| blaADC-190 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MK482717.1 | QBC36177.1 |
| blaADC-191 | Card DatabaseReference Gene CatalogReslit | 4 | CEPHALOSPORIN, carbapenems | Acinetobacter baumannii | - | 2023 | MK634301.1 | QBO66648.1 |
| blaADC-192 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | KU604557.1 | AOA49613.1 |
| blaADC-194 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter calcoaceticus | - | - | MK713327.1 | QBX33277.1 |
| blaADC-195 | Card DatabaseReference Gene CatalogReslit | 4 | CEPHALOSPORIN, ceftazidime | Acinetobacter baumannii | Brazil | 2025 | MK840871.1 | QCF61855.1 |
| blaADC-196 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MN249721.2 | QDY98381.2 |
| blaADC-197 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MN018169.1 | QEJ73994.1 |
| blaADC-198 | Card DatabaseReference Gene CatalogReslit | 4 | CEPHALOSPORIN, cephalosporins | Acinetobacter baumannii | Vietnam | 2025 | MN018171.1 | QEJ73996.1 |
| blaADC-199 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MN018172.1 | QEJ73997.1 |
| blaADC-200 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MN018173.1 | QEJ73998.1 |
| blaADC-201 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter pittii | - | - | MN018174.1 | QEJ73999.1 |
| blaADC-202 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter pittii | - | - | MN018175.1 | QEJ74000.1 |
| blaADC-203 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MN370445.1 | QEJ80825.1 |
| blaADC-204 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MN370446.1 | QEJ80826.1 |
| blaADC-205 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter calcoaceticus | - | - | MN370447.1 | QEJ80827.1 |
| blaADC-206 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter pittii | - | - | MN370448.1 | QEJ80828.1 |
| blaADC-207 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter pittii | - | - | MN370449.1 | QEJ80829.1 |
| blaADC-208 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter pittii | - | - | MN370450.1 | QEJ80830.1 |
| blaADC-209 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter pittii | - | - | MN370451.1 | QEJ80831.1 |
| blaADC-210 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter pittii | - | - | MN370452.1 | QEJ80832.1 |
| blaADC-211 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MN018170.1 | QEJ73995.1 |
| blaADC-212 | Card DatabaseReference Gene CatalogReslit | 5 | CEPHALOSPORIN, cephalosporins | Acinetobacter baumannii | Europe|United States | 2021 | NGEQ01000025.1 | OTN05897.1 |
| blaADC-213 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | NGFU01000029.1 | OTR53589.1 |
| blaADC-214 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | NGGD01000042.1 | OTR85897.1 |
| blaADC-215 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | NGHW01000028.1 | OTT53070.1 |
| blaADC-216 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | NGHX01000050.1 | OTT57830.1 |
| blaADC-217 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | NGHZ01000086.1 | OTT60833.1 |
| blaADC-218 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | NGIV01000033.1 | OTU52329.1 |
| blaADC-219 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | NGJF01000080.1 | OTU79690.1 |
| blaADC-220 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | NEQH01000054.1 | OVN99777.1 |
| blaADC-221 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter pittii | - | - | MN654470.1 | QGI88785.1 |
| blaADC-222 | Card DatabaseReference Gene CatalogReslit | 4 | CEPHALOSPORIN, cephalosporins | Acinetobacter baumannii | - | 2021 | MN603395.1 | QGX04216.1 |
| blaADC-223 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MN603396.1 | QGX04217.1 |
| blaADC-224 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MN603397.1 | QGX04218.1 |
| blaADC-225 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MN603399.1 | QGX04220.1 |
| blaADC-226 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MN603400.1 | QGX04221.1 |
| blaADC-227 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MN603401.1 | QGX04222.1 |
| blaADC-228 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MN603402.1 | QGX04223.1 |
| blaADC-229 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MN603403.1 | QGX04224.1 |
| blaADC-230 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MN603404.1 | QGX04225.1 |
| blaADC-231 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MN603406.1 | QGX04227.1 |
| blaADC-232 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MN603407.1 | QGX04228.1 |
| blaADC-233 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MN603408.1 | QGX04229.1 |
| blaADC-234 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | WUBY01000033.1 | KAF0597708.1 |
| blaADC-235 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | WTZL01000031.1 | KAF0620133.1 |
| blaADC-236 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | CP046898.1 | QLB34755.1 |
| blaADC-237 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | NGCA01000017.1 | OTK49191.1 |
| blaADC-238 | Card DatabaseReference Gene CatalogReslit | 4 | CEPHALOSPORIN, cefoxitin | Acinetobacter baumannii +1 | Peninsular Malaysia|Malaysia | 2025 | NGCF01000020.1 | OTK70618.1 |
| blaADC-239 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter nosocomialis | - | - | NGCS01000065.1 | OTL12117.1 |
| blaADC-24 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter pittii | - | - | AM283517.1 | CAK95237.1 |
| blaADC-240 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | NGDV01000059.1 | OTM22732.1 |
| blaADC-241 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | NGDW01000039.1 | OTM24148.1 |
| blaADC-242 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | NGEE01000017.1 | OTM59963.1 |
| blaADC-243 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | NGDB01000159.1 | OTL48012.1 |
| blaADC-244 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | NGDF01000073.1 | OTL60666.1 |
| blaADC-245 | Card DatabaseReference Gene CatalogReslit | 4 | CEPHALOSPORIN, cephalosporins | Acinetobacter pittii | Europe|Japan|Hong Kong|Mexico|US|China|Spain | 2025 | NGEN01000069.1 | OTM91601.1 |
| blaADC-246 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | NGEY01000028.1 | OTN27812.1 |
| blaADC-247 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | NGFV01000002.1 | OTR57744.1 |
| blaADC-248 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | NGJD01000012.1 | OTU75713.1 |
| blaADC-249 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | NGIG01000072.1 | OTT85755.1 |
| blaADC-250 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | NGGN01000005.1 | OTS26706.1 |
| blaADC-251 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | NGII01000039.1 | OTT95091.1 |
| blaADC-252 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter pittii | - | - | NGIO01000031.1 | OTU20214.1 |
| blaADC-253 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter pittii | - | - | NGIW01000020.1 | OTU44844.1 |
| blaADC-254 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | NGIB01000003.1 | OTT74418.1 |
| blaADC-255 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter nosocomialis | - | - | NGIH01000033.1 | OTT91454.1 |
| blaADC-256 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MW075278.1 | QRN78589.1 |
| blaADC-257 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MZ224611.1 | QVU28095.1 |
| blaADC-258 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | MZ224612.1 | QVU28094.1 |
| blaADC-259 | Card DatabaseReference Gene CatalogReslit | 3 | CEPHALOSPORIN, cephalosporins | Acinetobacter baumannii | Switzerland|France|Bahrain | 2022 | OK340849.1 | UBX38689.1 |
| blaADC-26 | Reference Gene CatalogReslit | 3 | CEPHALOSPORIN, ceftazidime +4 | Acinetobacter baumannii +1 | - | 2010, 2021 | GU591987.1 | ADG46043.1 |
| blaADC-260 | Card DatabaseReference Gene CatalogReslit | 3 | CEPHALOSPORIN, cephalosporins | Acinetobacter baumannii | Switzerland|France|Bahrain | 2022 | OK396701.1 | UCZ39549.1 |
| blaADC-262 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | OL901271.1 | UHO07582.1 |
| blaADC-263 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | OL901272.1 | UHO07583.1 |
| blaADC-264 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter calcoaceticus | - | - | OL901280.1 | UHO07591.1 |
| blaADC-265 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter pittii | - | - | OM572561.1 | ULU82599.1 |
| blaADC-266 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter nosocomialis | - | - | ON191578.1 | UOU25744.1 |
| blaADC-267 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | ON960904.1 | UTQ48801.1 |
| blaADC-268 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | ON651460.1 | UTS94213.1 |
| blaADC-269 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | ON651461.1 | UTS94214.1 |
| blaADC-270 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | ON651462.1 | UTS94215.1 |
| blaADC-271 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | ON651463.1 | UTS94216.1 |
| blaADC-272 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | ON651464.1 | UTS94217.1 |
| blaADC-273 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | ON651465.1 | UTS94218.1 |
| blaADC-274 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | ON651466.1 | UTS94219.1 |
| blaADC-275 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | ON651467.1 | UTS94220.1 |
| blaADC-276 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | ON651468.1 | UTS94221.1 |
| blaADC-277 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | ON651469.1 | UTS94222.1 |
| blaADC-278 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | ON651470.1 | UTS94223.1 |
| blaADC-279 | Card DatabaseReference Gene CatalogReslit | 3 | CEPHALOSPORIN, cefoxitin | Acinetobacter baumannii +1 | Peninsular Malaysia|Malaysia | 2025 | ON651471.1 | UTS94224.1 |
| blaADC-280 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | ON651472.1 | UTS94225.1 |
| blaADC-281 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter lactucae | - | - | ON651496.1 | UTS94249.1 |
| blaADC-282 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter pittii | - | - | ON651497.1 | UTS94250.1 |
| blaADC-283 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | OP131856.1 | UUM03672.1 |
| blaADC-284 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | OP297826.1 | UVU92350.1 |
| blaADC-285 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter pittii | - | - | OP297829.1 | UVU92353.1 |
| blaADC-286 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter pittii | - | - | OP745003.1 | UZF98454.1 |
| blaADC-287 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter pittii | - | - | OP745005.1 | UZF98456.1 |
| blaADC-288 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter pittii | - | - | OP745007.1 | UZF98458.1 |
| blaADC-289 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter nosocomialis | - | - | OP806904.1 | UZQ18804.1 |
| blaADC-29 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | EU604835.1 | ACC66195.1 |
| blaADC-290 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | OP806905.1 | UZQ18805.1 |
| blaADC-291 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | OQ408539.1 | WDE35083.1 |
| blaADC-293 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | OQ592373.1 | WEG44937.1 |
| blaADC-294 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | OQ592374.1 | WEG44938.1 |
| blaADC-295 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter sp. WC-141 | - | - | AMSS01000044.1 | EKU38981.1 |
| blaADC-302 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JAOXAU010000001.1 | MDC5490025.1 |
| blaADC-303 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JAOWYO010000004.1 | MDC5131430.1 |
| blaADC-304 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JANJCG010000001.1 | MDC5177796.1 |
| blaADC-305 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JAOWYW010000001.1 | MDC5206348.1 |
| blaADC-306 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JANJEG010000001.1 | MDC5547987.1 |
| blaADC-307 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JANJEC010000002.1 | MDC5515369.1 |
| blaADC-308 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JANJCP010000016.1 | MDC5119581.1 |
| blaADC-309 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JANJBJ010000001.1 | MDC4862281.1 |
| blaADC-310 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JANJCA010000001.1 | MDC5062159.1 |
| blaADC-311 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JANJDX010000001.1 | MDC5482482.1 |
| blaADC-312 | Card DatabaseReference Gene CatalogReslit | 3 | CEPHALOSPORIN, cephalosporins | Acinetobacter baumannii | Peninsular Malaysia|Malaysia | 2025 | JANJED010000023.1 | MDC5528210.1 |
| blaADC-313 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JANIZI010000005.1 | MDC4557711.1 |
| blaADC-314 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JANJCW010000001.1 | MDC5248995.1 |
| blaADC-315 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JAOWZW010000001.1 | MDC5406861.1 |
| blaADC-316 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JANIZP010000005.1 | MDC4596988.1 |
| blaADC-317 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JANIZQ010000004.1 | MDC4589794.1 |
| blaADC-318 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JANJBO010000013.1 | MDC4897557.1 |
| blaADC-319 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JAOWUQ010000001.1 | MDC4364731.1 |
| blaADC-32 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii NIPH 615 | - | - | APOV01000029.1 | ENU68675.1 |
| blaADC-320 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JAOWZM010000001.1 | MDC5360473.1 |
| blaADC-321 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JAOWVC010000002.1 | MDC4513545.1 |
| blaADC-322 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JANIXO010000004.1 | MDC4290945.1 |
| blaADC-323 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JANIXZ010000001.1 | MDC4357889.1 |
| blaADC-324 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JAOYRN010000002.1 | MDC5633961.1 |
| blaADC-325 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JANIZX010000006.1 | MDC4671831.1 |
| blaADC-326 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JAOXAC010000001.1 | MDC5297294.1 |
| blaADC-327 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JANIYJ010000001.1 | MDC4416129.1 |
| blaADC-328 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JAOWXP010000001.1 | MDC4995114.1 |
| blaADC-329 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JANJCJ010000001.1 | MDC5109664.1 |
| blaADC-330 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JAOVSX010000002.1 | MDC5665782.1 |
| blaADC-331 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JAOWUO010000003.1 | MDC4333491.1 |
| blaADC-332 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JANJDG010000058.1 | MDC5390807.1 |
| blaADC-333 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JANJAT010000001.1 | MDC4787251.1 |
| blaADC-334 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter nosocomialis | - | - | OR102459.1 | WIU89416.1 |
| blaADC-335 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter seifertii | - | - | OR102460.1 | WIU89417.1 |
| blaADC-336 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | OR232962.1 | WKB14824.1 |
| blaADC-337 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | OR232963.1 | WKB14825.1 |
| blaADC-338 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | OR367331.1 | WLF01974.1 |
| blaADC-339 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | OR367332.1 | WLF01975.1 |
| blaADC-340 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | OR367333.1 | WLF01976.1 |
| blaADC-341 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | OR367334.1 | WLF01977.1 |
| blaADC-342 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | OR367335.1 | WLF01978.1 |
| blaADC-343 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter pittii | - | - | LC777322.1 | BER91151.1 |
| blaADC-344 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | OR754316.1 | WOW71214.1 |
| blaADC-345 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | OR754317.1 | WOW71215.1 |
| blaADC-346 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | LC794503.1 | BEV74606.1 |
| blaADC-347 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PP328945.1 | WVW91698.1 |
| blaADC-348 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PP328946.1 | WVW91699.1 |
| blaADC-349 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PP328947.1 | WVW91700.1 |
| blaADC-350 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter nosocomialis | - | - | PP328948.1 | WVW91701.1 |
| blaADC-351 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter pittii | - | - | PP328949.1 | WVW91702.1 |
| blaADC-352 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter pittii | - | - | PP328950.1 | WVW91703.1 |
| blaADC-353 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter sp. | - | - | PP328951.1 | WVW91704.1 |
| blaADC-354 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PQ203893.1 | XGB73521.1 |
| blaADC-355 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PQ203894.1 | XGB73522.1 |
| blaADC-356 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PQ203895.1 | XGB73523.1 |
| blaADC-357 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter pittii | - | - | PQ203896.1 | XGB73524.1 |
| blaADC-358 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter nosocomialis | - | - | PQ203897.1 | XGB73525.1 |
| blaADC-359 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PQ323407.1 | XHE66941.1 |
| blaADC-360 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PQ768491.1 | XLV50101.1 |
| blaADC-361 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PQ768492.1 | XLV50102.1 |
| blaADC-362 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PQ768493.1 | XLV50103.1 |
| blaADC-363 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PQ768494.1 | XLV50104.1 |
| blaADC-364 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter pittii | - | - | PQ768495.1 | XLV50105.1 |
| blaADC-365 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter pittii | - | - | PQ768496.1 | XLV50106.1 |
| blaADC-366 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter lactucae | - | - | PQ768497.1 | XLV50107.1 |
| blaADC-367 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter nosocomialis | - | - | PQ768498.1 | XLV50108.1 |
| blaADC-368 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | CP082952.1 | UBK09015.1 |
| blaADC-369 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PV054794.1 | XOA00362.1 |
| blaADC-370 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PV054795.1 | XOA00363.1 |
| blaADC-371 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PV054796.1 | XOA00364.1 |
| blaADC-372 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PV054797.1 | XOA00365.1 |
| blaADC-373 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PV054798.1 | XOA00366.1 |
| blaADC-374 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PV054799.1 | XOA00367.1 |
| blaADC-375 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PV054800.1 | XOA00368.1 |
| blaADC-376 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PV054802.1 | XOA00370.1 |
| blaADC-377 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PV054803.1 | XOA00371.1 |
| blaADC-378 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PV054804.1 | XOA00372.1 |
| blaADC-379 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PV054805.1 | XOA00373.1 |
| blaADC-38 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | EU652243.1 | ACC95873.1 |
| blaADC-380 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PV054807.1 | XOA00375.1 |
| blaADC-381 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PV054808.1 | XOA00376.1 |
| blaADC-382 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PV054809.1 | XOA00377.1 |
| blaADC-383 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PV054810.1 | XOA00378.1 |
| blaADC-384 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter pittii | - | - | PV054811.1 | XOA00379.1 |
| blaADC-385 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter pittii | - | - | PV054812.1 | XOA00380.1 |
| blaADC-386 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter pittii | - | - | PV054813.1 | XOA00381.1 |
| blaADC-387 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter pittii | - | - | PV054814.1 | XOA00382.1 |
| blaADC-388 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter pittii | - | - | PV054815.1 | XOA00383.1 |
| blaADC-389 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter geminorum | - | - | PV054816.1 | XOA00384.1 |
| blaADC-390 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter nosocomialis | - | - | PV054817.1 | XOA00385.1 |
| blaADC-391 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter nosocomialis | - | - | PV054818.1 | XOA00386.1 |
| blaADC-392 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter nosocomialis | - | - | PV054819.1 | XOA00387.1 |
| blaADC-393 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter nosocomialis | - | - | PV054820.1 | XOA00388.1 |
| blaADC-394 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter lactucae | - | - | PV054821.1 | XOA00389.1 |
| blaADC-395 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter oleivorans | - | - | PV054822.1 | XOA00390.1 |
| blaADC-396 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PV184581.1 | XPO98262.1 |
| blaADC-397 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PV184582.1 | XPO98263.1 |
| blaADC-398 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PV672115.1 | XUK78462.1 |
| blaADC-399 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PV672116.1 | XUK78465.1 |
| blaADC-400 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PV672117.1 | XUK78468.1 |
| blaADC-401 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PV672119.1 | XUK78474.1 |
| blaADC-402 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PX654915.1 | YCB24315.1 |
| blaADC-403 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PX654916.1 | YCB24316.1 |
| blaADC-404 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PX753243.2 | YCH96039.1 |
| blaADC-405 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PX753244.2 | YCH96040.1 |
| blaADC-406 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter sp. 25A4986 | - | - | PX904226.1 | YCQ82297.1 |
| blaADC-407 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PZ137893.1 | YDL25837.1 |
| blaADC-408 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | PZ137894.1 | YDL25838.1 |
| blaADC-50 | Reference Gene CatalogReslit | 2 | CEPHALOSPORIN, ceftazidime +1 | Acinetobacter baumannii +1 | Europe | 2024 | GU591982.1 | ADG46038.1 |
| blaADC-52 | Card DatabaseReference Gene CatalogReslit | 5 | CEPHALOSPORIN, ceftazidime +3 | Acinetobacter baumannii +1 | - | 2010, 2021 | GU591986.1 | ADG46042.1 |
| blaADC-54 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | HM437231.1 | ADK35761.1 |
| blaADC-58 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JQ319653.1 | AFG25594.1 |
| blaADC-59 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JQ319654.1 | AFG25595.1 |
| blaADC-60 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JQ692087.1 | AFH53180.1 |
| blaADC-62 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JQ867374.1 | AFK24475.1 |
| blaADC-63 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JQ911781.1 | AFM80040.1 |
| blaADC-65 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JX109941.1 | AFP73417.1 |
| blaADC-66 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | JX109942.1 | AFP73418.1 |
| blaADC-67 | Card DatabaseReference Gene CatalogReslit | 4 | CEPHALOSPORIN, beta lactams | Acinetobacter baumannii | China | 2014 | JQ037817.1 | AEZ36052.1 |
| blaADC-70 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter pittii | - | - | LLIO01000035.1 | KQG48886.1 |
| blaADC-83 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter sp. MRSN7700 | - | - | KX599387.1 | ANW47146.1 |
| blaADC-84 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | KX599390.1 | ANW47149.1 |
| blaADC-85 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter sp. MRSN7616 | - | - | KX599383.1 | ANW47142.1 |
| blaADC-86 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter sp. MRSN7664 | - | - | KX599384.1 | ANW47143.1 |
| blaADC-87 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | KX599395.1 | ANW47154.1 |
| blaADC-88 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | KX599376.1 | ANW47135.1 |
| blaADC-89 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | KX599377.1 | ANW47136.1 |
| blaADC-90 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | KX599388.1 | ANW47147.1 |
| blaADC-91 | Card DatabaseReference Gene CatalogReslit | 4 | CEPHALOSPORIN, cephalosporins | Acinetobacter baumannii | Switzerland|France|Bahrain | 2022 | KX599373.1 | ANW47132.1 |
| blaADC-92 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | KX599375.1 | ANW47134.1 |
| blaADC-93 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | KX599386.1 | ANW47145.1 |
| blaADC-94 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | KX599378.1 | ANW47137.1 |
| blaADC-95 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | KX599394.1 | ANW47153.1 |
| blaADC-96 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | KX599391.1 | ANW47150.1 |
| blaADC-97 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | KX599380.1 | ANW47139.1 |
| blaADC-98 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | - | KX599379.1 | ANW47138.1 |
| blaADC-99 | Card DatabaseReference Gene CatalogReslit | 5 | CEPHALOSPORIN, ampicillin +3 | Acinetobacter baumannii +2 | Peninsular Malaysia|Malaysia | 2019, 2025 | KX599381.1 | ANW47140.1 |
| blaADC-109 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | 2006 | NG_064669.1 | WP_136512052.1 |
| blaADC-112 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | 2008 | NG_064671.1 | WP_136512054.1 |
| blaADC-113 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | 2008 | NG_064672.1 | WP_136512055.1 |
| blaADC-115 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii TYTH-1 | - | 2012 | NG_064674.1 | WP_001211215.1 |
| blaADC-116 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii AB4A3 | - | 2013 | NG_064675.1 | WP_017816757.1 |
| blaADC-117 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii AA-014 | - | 2015 | NG_064676.1 | WP_002157727.1 |
| blaADC-144 | Card DatabaseReference Gene CatalogReslit | 3 | CEPHALOSPORIN, cefoxitin +2 | Acinetobacter baumannii AB_TG2030 +1 | Europe | 2011, 2025 | NG_064699.1 | WP_001211214.1 |
| blaADC-149 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter pittii PHEA-2 | - | 2011 | NG_064704.1 | WP_014207272.1 |
| blaADC-153 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | 2018 | NG_055657.1 | WP_099156045.1 |
| blaADC-177 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | 2011 | NG_061393.1 | WP_114699269.1 |
| blaADC-193 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter oleivorans DR1 | - | 2010 | NG_064716.1 | WP_013197184.1 |
| blaADC-30 | Card DatabaseReference Gene CatalogReslit | 12 | ceftazidime, cefotaxime +6 | Acinetobacter baumannii +3 | China, South Korea, Europe|United States, Switzerland|France|Bahrain, Italy, East China | 2010, 2011, 2019, 2021, 2022, 2023, 2024 | JF265068.1 | AEL30572.1 |
| blaADC-33 | Card DatabaseReference Gene CatalogReslit | 8 | ceftazidime, cefepime +4 | Acinetobacter baumannii +2 | USA|China|Europe|Asia|South America|North America|Middle East | 2010, 2021, 2023, 2025 | NG_056059.1 | WP_001211220.1 |
| blaADC-51 | Card DatabaseReference Gene CatalogReslit | 4 | ceftazidime, cefotaxime +3 | Acinetobacter baumannii +1 | - | 2010 | NG_048662.1 | WP_063857805.1 |
| blaADC-53 | Card DatabaseReference Gene CatalogReslit | 4 | ceftazidime, cefotaxime +3 | Acinetobacter baumannii +1 | - | 2010 | NG_048664.1 | WP_063857806.1 |
| blaADC-56 | Card DatabaseReference Gene CatalogReslit | 6 | cefepime, CEPHALOSPORIN +4 | Acinetobacter baumannii +1 | Global | 2011, 2021, 2022 | HQ662682.1 | AEG47700.1 |
| blaADC-57 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Acinetobacter baumannii | - | 2013 | NG_051494.1 | WP_001211226.1 |
| blaADC-6 | Card DatabaseReference Gene CatalogReslit | 5 | CEPHALOSPORIN, cephalosporins +2 | Acinetobacter baumannii | Italy, China | 2004, 2022, 2025 | MG601730.1 | AUD40659.1 |
| blaADC-80 | Card DatabaseReference Gene CatalogReslit | 4 | CEPHALOSPORIN, cefepime | Acinetobacter baumannii | - | 2020, 2021 | NG_048686.1 | WP_029424536.1 |
| blaADC-82 | Card DatabaseReference Gene CatalogReslit | 4 | CEPHALOSPORIN, cefepime | Acinetobacter baumannii 1552865 +2 | - | 2017, 2021 | JEXY01000001.1 | EXE65374.1 |
| blaADC-1 | Card DatabaseReference Gene CatalogReslit | 3 | CEPHALOSPORIN, ertapenem | Acinetobacter baumannii +1 | - | 2000, 2025 | AJ009979.1 | CAB77444.1 |
| blaADC-2 | Card DatabaseReference Gene CatalogReslit | 4 | CEPHALOSPORIN, beta lactams +3 | Oligella urethralis +1 | Chongqing|China | 2003, 2019, 2024 | AY177427.1 | AAO43172.1 |
| blaADC-3 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | 2003 | AY178995.1 | AAO59456.1 |
| blaADC-4 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | 2003 | AY178996.1 | AAO59457.1 |
| blaADC-5 | Card DatabaseReference Gene CatalogReslit | 6 | CEPHALOSPORIN, carbapenems +4 | Acinetobacter pittii +2 | Germany, Taiwan, Paraguay|Northern Spain | 2004, 2020, 2023, 2025 | AJ575184.1 | CAE00827.1 |
| blaADC-7 | Card DatabaseReference Gene CatalogReslit | 13 | cefepime, ceftazidime +8 | Acinetobacter baumannii +4 | Colombia, Philadelphia, Pennsylvania | 2005, 2012, 2014, 2015, 2017, 2018, 2020, 2025 | AY648950 | AAT70411.1 |
| blaADC | Reslit | 28 | ceftazidime, cefepime +9 | Acinetobacter sp. +6 | United States, United States|Iraq|Germany, Taiwan, China|Beijing, China, Germany, East Africa|Kenya, Sweden|Australia|Japan|France|United Arab Emirates|India|South Africa|Netherlands|Canada|China, Nepal, Taiwan|New Jersey, USA, Japan, Egypt, Argentina, Brazil, India, Europe, China, South Korea, Terengganu, Malaysia|Malaysia | 2006, 2008, 2010, 2013, 2016, 2017, 2018, 2020, 2021, 2023, 2024, 2025 | FJ744160|FJ744161|FJ744162|FJ744163|GQ864268|FJ744165|FJ744164|GQ926879 | - |
| blaADC-8 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baylyi ADP1 | - | 2007 | AM293332.3 | CAL25116.3 |
| blaADC-14 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter pittii | - | 2008 | AM283527.1 | CAK95247.1 |
| blaADC-25 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 26 | UNKNOWN BETA-LACTAM, CEPHALOSPORIN +15 | Acinetobacter baumannii +5 | Switzerland, Serbia, South Korea, Argentina, Thailand|Nepal, Taiwan, Italy, Switzerland|France|Bahrain, Thailand, Iraq|Afghanistan, Germany, Saudi Arabia|Riyadh|Jeddah|Makkah|Al Jouf|Aseer|Najran|Eastern Region|Western Region|Northern Region|Southern Region, Central Greece, Egypt, India, China, Europe|North America|South America, Kano, Nigeria|Nigeria, Peninsular Malaysia|Malaysia | 2008, 2011, 2016, 2019, 2020, 2021, 2022, 2023, 2024, 2025 | EF016355.1 | ABK34773.1 |
| blaADC-39 | Card DatabaseReference Gene CatalogReslit | 3 | cephalosporins, CEPHALOSPORIN | Acinetobacter baumannii | Belgium | 2008 | EU652244 | ACC95874.1 |
| blaADC-12 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter pittii | - | 2009 | AM283529.1 | CAK95249.1 |
| blaADC-13 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter pittii | - | 2009 | AM283528.2 | CAK95248.2 |
| blaADC-15 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter pittii | - | 2009 | AM283526.1 | CAK95246.1 |
| blaADC-16 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter pittii | - | 2009 | AM283525.1 | CAK95245.1 |
| blaADC-17 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter pittii | - | 2009 | AM283524.1 | CAK95244.1 |
| blaADC-18 | Card DatabaseReference Gene CatalogReslit | 4 | CEPHALOSPORIN, cephalosporins | Acinetobacter pittii +1 | Europe|South Korea, Europe|Japan|Hong Kong|Mexico|US|China|Spain | 2009, 2022, 2025 | AM283523.1 | CAK95243.1 |
| blaADC-19 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter pittii | - | 2009 | AM283522.1 | CAK95242.1 |
| blaADC-20 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter pittii | - | 2009 | AM283521.1 | CAK95241.1 |
| blaADC-21 | Card DatabaseReference Gene CatalogReslit | 3 | CEPHALOSPORIN, cephalosporins | Acinetobacter pittii | Europe|Japan|Hong Kong|Mexico|US|China|Spain | 2009, 2025 | AM283520.1 | CAK95240.1 |
| blaADC-22 | Card DatabaseReference Gene CatalogReslit | 3 | CEPHALOSPORIN, ceftazidime +1 | Acinetobacter pittii | South Korea | 2009, 2019 | AM283519.1 | CAK95239.1 |
| blaADC-23 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter pittii | - | 2009 | AM283518.1 | CAK95238.1 |
| blaADC-41 | Card DatabaseReference Gene CatalogReslit | 3 | CEPHALOSPORIN, ceftazidime +1 | Acinetobacter pittii | South Korea | 2010, 2019 | FJ744160.1 | ACN62070.1 |
| blaADC-42 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter pittii | - | 2010 | FJ744161.1 | ACN62071.1 |
| blaADC-43 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter pittii | - | 2010 | FJ744162.1 | ACN62072.1 |
| blaADC-44 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter pittii | - | 2010 | FJ744163.1 | ACN62073.1 |
| blaADC-11 | Card DatabaseReference Gene CatalogReslit | 3 | CEPHALOSPORIN, cephalosporins | Acinetobacter baumannii AYE +1 | - | 2010, 2021 | GU591983.1 | ADG46039.1 |
| bla_ADC | Reslit | 1 | ceftazidime, carbapenems | Acinetobacter baumannii A118 | Argentina | 2011 | AEOW00000000 | - |
| blaADC-261 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | 2011 | OL774887.1 | UGW32408.1 |
| blaADC-31 | Card DatabaseReference Gene CatalogReslit | 3 | CEPHALOSPORIN, ceftazidime +1 | Acinetobacter baumannii 1656-2 +1 | South Korea | 2011, 2019 | CP001921.1 | ADX04315.1 |
| adc | Reslit | 2 | carbapenems, imipenem +1 | Acinetobacter baumannii | China|Beijing, China, Inner Mongolia | 2013, 2022 | CP003846|CP003887|CP003849|CP003850|CP003888|CP003847|CP003848|CP003907|CP003908 | - |
| bla(ADC) | Reslit | 1 | carbapenems | Acinetobacter baumannii | East Africa|Kenya | 2013 | HQ141279|HQ148722|HQ258925 | - |
| bla_ADC-69 | Reslit | 1 | carbapenems | Acinetobacter nosocomialis +1 | China | 2014 | KF134400|KF134401|KF134402 | - |
| bla_ADC-70 | Reslit | 1 | carbapenems | Acinetobacter nosocomialis +1 | China | 2014 | KF134400|KF134401|KF134402 | - |
| bla_ADC-71 | Reslit | 1 | carbapenems | Acinetobacter nosocomialis +1 | China | 2014 | KF134400|KF134401|KF134402 | - |
| blaADC-68 | Card DatabaseReference Gene CatalogReslit | 3 | CARBAPENEM, cephalosporins | Acinetobacter baumannii | Peninsular Malaysia|Malaysia | 2014, 2025 | KC866352.1 | AGL39360.1 |
| blaADC-61 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | 2015 | JQ753702.1 | AFI56570.1 |
| blaADC-74 | Card DatabaseReference Gene CatalogReslit | 4 | CEPHALOSPORIN, cephalosporins +1 | Acinetobacter baumannii | Lebanon | 2016, 2020, 2021 | KP881234.1 | ALA14809.1 |
| blaADC-75 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | 2016 | KP881235.1 | ALA14810.1 |
| blaADC-76 | Card DatabaseReference Gene CatalogReslit | 4 | CEPHALOSPORIN, cefepime +1 | Acinetobacter baumannii +9 | Peninsular Malaysia|Malaysia | 2016, 2021, 2025 | KP881236.1 | ALA14811.1 |
| blaADC-77 | Card DatabaseReference Gene CatalogReslit | 3 | CEPHALOSPORIN, ceftazidime +1 | Acinetobacter baumannii | South Korea | 2016, 2019 | KP881237.1 | ALA14812.1 |
| blaADC-78 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | 2016 | KP881238.1 | ALA14813.1 |
| blaADC-79 | Card DatabaseReference Gene CatalogReslit | 4 | CEPHALOSPORIN, cefepime +1 | Acinetobacter baumannii | Nigeria | 2016, 2021, 2025 | KP881239.1 | ALA14814.1 |
| blaADC-81 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter baumannii | - | 2016 | KP881241.1 | ALA14816.1 |
| blaADC-73 | Card DatabaseReference Gene CatalogReslit | 13 | CEPHALOSPORIN, cephalosporins +6 | Acinetobacter baumannii | Lebanon, Egypt, Switzerland|France|Bahrain, Italy, East China, China, Vietnam, Paraguay|Northern Spain, China|Korea|Japan | 2018, 2020, 2021, 2022, 2023, 2024, 2025 | KP881233.1 | ALA14808.1 |
| blaADC-like | Reslit | 1 | cefotaxime, ceftazidime | Acinetobacter baumannii | Brazil | 2019 | PKCA01000000|PYSX01000000 | - |
| blaADC–like | Reslit | 1 | cefotaxime | Acinetobacter baumannii | Brazil | 2019 | PKCA01000000|PYSX01000000 | - |
| blaADC–25 | Reslit | 1 | ampicillin sulbactam, ceftazidime +2 | Acinetobacter seifertii SAb133 | Brazil | 2019 | SNSA00000000 | - |
| bla_ADC-33 | Reslit | 1 | ceftazidime, cefepime +1 | Acinetobacter baumannii | - | 2023 | 8CUL|8CUM|8CUO|8CUP|8CUQ | - |
| bla_ADC-51 | Reslit | 1 | ceftazidime, cefepime +1 | Acinetobacter baumannii | - | 2023 | 8CUL|8CUM|8CUO|8CUP|8CUQ | - |
| bla(ADC-57) | Reslit | 1 | carbapenems | Acinetobacter baumannii | Egypt | 2023 | JANBZS000000000 | - |
| blaADC-292 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Acinetobacter pittii | - | 2024 | JARCHN010000001.1 | MDE4038918.1 |
| blaADC-1TM | Reslit | 1 | meropenem, ertapenem +1 | Acinetobacter baumannii +1 | - | 2025 | KC866352.1 | - |
| blaADC-169 variant | Reslit | 1 | cefoxitin | Acinetobacter baumannii 19056 | Peninsular Malaysia|Malaysia | 2025 | JBNPBH000000000|JBNPBI000000000|JBNPBJ000000000|JBNPBK000000000|JBNPBL000000000|JBNPBM000000000|JBNPBN000000000|JBNPBO000000000|JBNPBP000000000 | - |
| blaADC-312 variant | Reslit | 1 | cefoxitin | Acinetobacter baumannii 19058 | Peninsular Malaysia|Malaysia | 2025 | JBNPBH000000000|JBNPBI000000000|JBNPBJ000000000|JBNPBK000000000|JBNPBL000000000|JBNPBM000000000|JBNPBN000000000|JBNPBO000000000|JBNPBP000000000 | - |
| blaADC-158 variant | Reslit | 1 | cefoxitin | Acinetobacter baumannii 19063 | Peninsular Malaysia|Malaysia | 2025 | JBNPBH000000000|JBNPBI000000000|JBNPBJ000000000|JBNPBK000000000|JBNPBL000000000|JBNPBM000000000|JBNPBN000000000|JBNPBO000000000|JBNPBP000000000 | - |
Cloning, nucleotide sequencing, and analysis of the gene encoding an AmpC beta-lactamase in Acinetobacter baumannii.
Cloning, nucleotide sequencing, and analysis of the gene encoding an AmpC beta-lactamase in Acinetobacter baumannii., [Identification of a new subtype of blaADC produced by Acinetobacter baumannii isolated in children].
Chromosomal integration of a cephalosporinase gene from Acinetobacter baumannii into Oligella urethralis as a source of acquired resistance to beta-lactams.
Chromosomal integration of a cephalosporinase gene from Acinetobacter baumannii into Oligella urethralis as a source of acquired resistance to beta-lactams.
Chromosomal integration of a cephalosporinase gene from Acinetobacter baumannii into Oligella urethralis as a source of acquired resistance to beta-lactams.
Chromosomal integration of a cephalosporinase gene from Acinetobacter baumannii into Oligella urethralis as a source of acquired resistance to beta-lactams.
Chromosomal integration of a cephalosporinase gene from Acinetobacter baumannii into Oligella urethralis as a source of acquired resistance to beta-lactams.
Chromosomal integration of a cephalosporinase gene from Acinetobacter baumannii into Oligella urethralis as a source of acquired resistance to beta-lactams.
Genetic environment and transcription of ampC in an Acinetobacter baumannii clinical isolate.
Genetic environment and transcription of ampC in an Acinetobacter baumannii clinical isolate.
Molecular characterization of the gene encoding a new AmpC beta-lactamase in a clinical strain of acinetobacter genomic species 3.
Molecular characterization of the gene encoding a new AmpC beta-lactamase in a clinical strain of acinetobacter genomic species 3.
Identification of a new allelic variant of the Acinetobacter baumannii cephalosporinase, ADC-7 beta-lactamase: defining a unique family of class C enzymes.
The study identifies a new allelic variant of the Acinetobacter baumannii cephalosporinase, ADC-7 beta-lactamase, which confers resistance to several cephalosporins including cefepime, ceftazidime, and cefotaxime.
Identification of a new allelic variant of the Acinetobacter baumannii cephalosporinase, ADC-7 beta-lactamase: defining a unique family of class C enzymes.
Identification of a new allelic variant of the Acinetobacter baumannii cephalosporinase, ADC-7 beta-lactamase: defining a unique family of class C enzymes.
Cephalosporinase over-expression resulting from insertion of ISAba1 in Acinetobacter baumannii.
Cephalosporinase over-expression resulting from insertion of ISAba1 in Acinetobacter baumannii.
Analysis of antibiotic resistance genes in multidrug-resistant Acinetobacter sp. isolates from military and civilian patients treated at the Walter Reed Army Medical Center.
The study identified multiple antibiotic resistance genes in multidrug-resistant Acinetobacter sp. isolates, including bla ADC, bla OXA-69-like, bla OXA-23-like, bla OXA-58-like, bla TEM, bla PER, aacC1, aacC2, aadA1, aadB, and aphA6, which confer resistance to various antibiotics such as ceftazidime, cefepime, imipenem, meropenem, ampicillin, ampicillin-sulbactam, gentamicin, tobramycin, streptomycin, spectinomycin, amikacin, kanamycin, and neomycin.
Molecular characterization of the gene encoding a new AmpC beta-lactamase in Acinetobacter baylyi.
Molecular characterization of the gene encoding a new AmpC beta-lactamase in Acinetobacter baylyi.
False extended-spectrum beta-lactamase detection in Acinetobacter spp. due to intrinsic susceptibility to clavulanic acid.
False extended-spectrum beta-lactamase detection in Acinetobacter spp. due to intrinsic susceptibility to clavulanic acid.
An outbreak of carbapenem-resistant Acinetobacter baumannii producing OXA-23 carbapenemase in western China.
An outbreak of carbapenem-resistant Acinetobacter baumannii producing OXA-23 carbapenemase in western China.
An outbreak of carbapenem-resistant Acinetobacter baumannii producing OXA-23 carbapenemase in western China.
An outbreak of carbapenem-resistant Acinetobacter baumannii producing OXA-23 carbapenemase in western China.
Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City.
Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City.
Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City.
Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City.
Occupational transmission of Acinetobacter baumannii from a United States serviceman wounded in Iraq to a health care worker.
The study identifies β-lactamase genes blaTEM, blaADC, and blaOXA-51/69-like, aminoglycoside-modifying enzymes aacC1 and aadA1, and quinolone resistance mutations in gyrA and parC in multidrug-resistant Acinetobacter baumannii isolates from a healthcare worker and a patient.
Carbapenem-resistant Acinetobacter baumannii isolates expressing the blaOXA-23 gene associated with ISAba4 in Belgium.
The study identifies the blaOXA-23 gene associated with ISAba4 in carbapenem-resistant Acinetobacter baumannii isolates in Belgium, along with a novel blaADC-39 allele.
Carbapenem-resistant Acinetobacter baumannii isolates expressing the blaOXA-23 gene associated with ISAba4 in Belgium.
Carbapenem-resistant Acinetobacter baumannii isolates expressing the blaOXA-23 gene associated with ISAba4 in Belgium.
Genetic variability among ampC genes from acinetobacter genomic species 3.
Genetic variability among ampC genes from acinetobacter genomic species 3.
Genetic variability among ampC genes from acinetobacter genomic species 3.
Genetic variability among ampC genes from acinetobacter genomic species 3.
Genetic variability among ampC genes from acinetobacter genomic species 3.
Genetic variability among ampC genes from acinetobacter genomic species 3.
Genetic variability among ampC genes from acinetobacter genomic species 3.
Genetic variability among ampC genes from acinetobacter genomic species 3.
Genetic variability among ampC genes from acinetobacter genomic species 3.
Genetic variability among ampC genes from acinetobacter genomic species 3.
Genetic variability among ampC genes from acinetobacter genomic species 3.
Genetic variability among ampC genes from acinetobacter genomic species 3.
Genetic variability among ampC genes from acinetobacter genomic species 3.
Genetic variability among ampC genes from acinetobacter genomic species 3.
Genetic variability among ampC genes from acinetobacter genomic species 3.
Genetic variability among ampC genes from acinetobacter genomic species 3.
Genetic variability among ampC genes from acinetobacter genomic species 3.
Genetic variability among ampC genes from acinetobacter genomic species 3.
Genetic variability among ampC genes from acinetobacter genomic species 3.
Genetic variability among ampC genes from acinetobacter genomic species 3.
Genetic variability among ampC genes from acinetobacter genomic species 3.
Genetic variability among ampC genes from acinetobacter genomic species 3.
Inhibition of the class C beta-lactamase from Acinetobacter spp.: insights into effective inhibitor design.
The study identifies the class C beta-lactamase from Acinetobacter baumannii (blaADC) as a target for inhibitor design. The boronic acid derivatives, particularly compound 5, show potent inhibition of blaADC, reducing MICs of ceftazidime and cefotaxime in E. coli DH10B.
Molecular characterization of beta-lactamase genes and their genetic structures in Acinetobacter genospecies 3 isolates in Taiwan.
The study identified various beta-lactamase genes, including bla IMP-1, bla IMP-8, bla OXA-58, bla VEB-3, and bla ADC, which confer resistance to beta-lactam antibiotics in Acinetobacter genospecies 3 isolates in Taiwan.
Molecular characterization of beta-lactamase genes and their genetic structures in Acinetobacter genospecies 3 isolates in Taiwan.
Molecular characterization of beta-lactamase genes and their genetic structures in Acinetobacter genospecies 3 isolates in Taiwan.
Molecular characterization of beta-lactamase genes and their genetic structures in Acinetobacter genospecies 3 isolates in Taiwan.
Molecular characterization of beta-lactamase genes and their genetic structures in Acinetobacter genospecies 3 isolates in Taiwan.
Molecular characterization of beta-lactamase genes and their genetic structures in Acinetobacter genospecies 3 isolates in Taiwan.
Molecular characterization of beta-lactamase genes and their genetic structures in Acinetobacter genospecies 3 isolates in Taiwan.
Molecular characterization of beta-lactamase genes and their genetic structures in Acinetobacter genospecies 3 isolates in Taiwan.
Molecular characterization of beta-lactamase genes and their genetic structures in Acinetobacter genospecies 3 isolates in Taiwan.
Extended-spectrum cephalosporinase in Acinetobacter baumannii.
The study characterizes ADC-33, an extended-spectrum AmpC beta-lactamase from Acinetobacter baumannii, which confers resistance to expanded-spectrum cephalosporins and monobactams through specific amino acid substitutions and a duplication in the Ω-loop.
Extended-spectrum cephalosporinase in Acinetobacter baumannii.
Extended-spectrum cephalosporinase in Acinetobacter baumannii.
Extended-spectrum cephalosporinase in Acinetobacter baumannii.
Extended-spectrum cephalosporinase in Acinetobacter baumannii.
Complete genome sequence of the diesel-degrading Acinetobacter sp. strain DR1.
Complete genome sequence of the diesel-degrading Acinetobacter sp. strain DR1.
Genetic and functional variability of AmpC-type beta-lactamases from Acinetobacter baumannii.
The study identifies five AmpC beta-lactamases (ADC-26, ADC-30, ADC-51, ADC-52, and ADC-53) from ceftazidime-resistant Acinetobacter baumannii isolates, with some showing increased resistance to broad-spectrum cephalosporins.
Genetic and functional variability of AmpC-type beta-lactamases from Acinetobacter baumannii.
The study identifies five AmpC beta-lactamases (ADC-26, ADC-30, ADC-51, ADC-52, and ADC-53) from ceftazidime-resistant Acinetobacter baumannii isolates, with some showing increased resistance to broad-spectrum cephalosporins.
Genetic and functional variability of AmpC-type beta-lactamases from Acinetobacter baumannii.
The study identifies five AmpC beta-lactamases (ADC-26, ADC-30, ADC-51, ADC-52, and ADC-53) from ceftazidime-resistant Acinetobacter baumannii isolates, with some showing increased resistance to broad-spectrum cephalosporins.
Genetic and functional variability of AmpC-type beta-lactamases from Acinetobacter baumannii.
The study identifies five AmpC beta-lactamases (ADC-26, ADC-30, ADC-51, ADC-52, and ADC-53) from ceftazidime-resistant Acinetobacter baumannii isolates, with some showing increased resistance to broad-spectrum cephalosporins.
Genetic and functional variability of AmpC-type beta-lactamases from Acinetobacter baumannii.
The study identifies five AmpC beta-lactamases (ADC-26, ADC-30, ADC-51, ADC-52, and ADC-53) from ceftazidime-resistant Acinetobacter baumannii isolates, with some showing increased resistance to broad-spectrum cephalosporins.
Genetic and functional variability of AmpC-type β-lactamases from Acinetobacter baumannii.
Genetic and functional variability of AmpC-type β-lactamases from Acinetobacter baumannii.
Genetic and functional variability of AmpC-type β-lactamases from Acinetobacter baumannii.
Genetic and functional variability of AmpC-type β-lactamases from Acinetobacter baumannii.
Genomic analysis of Acinetobacter baumannii A118 by comparison of optical maps: identification of structures related to its susceptibility phenotype.
The study identifies the absence of the AbaR-type resistance island and the tet(A) gene in Acinetobacter baumannii A118, which may explain its susceptibility to various antibiotics. It also characterizes genes such as cat, bla_ADC, bla_OXA-51-like, carO, and pbp2, which are involved in resistance to chloramphenicol, cephalosporins, carbapenems, and other antibiotics.
Genome sequence of Acinetobacter calcoaceticus PHEA-2, isolated from industry wastewater.
Genome sequence of Acinetobacter calcoaceticus PHEA-2, isolated from industry wastewater.
Acinetobacter baumannii isolates from pets and horses in Switzerland: molecular characterization and clinical data.
The study identified several AMR genes and mutations in Acinetobacter baumannii isolates from pets and horses in Switzerland, including blaOXA-66, blaADC-25, blaTEM-1, aacC2, aadA1, aacC1, IS1133, ISAb1, and mutations in gyrA and parC genes associated with resistance to carbapenems, cephalosporins, piperacillin/tazobactam, gentamicin, and ciprofloxacin.
Extended-spectrum AmpC cephalosporinase in Acinetobacter baumannii: ADC-56 confers resistance to cefepime.
ADC-56, a novel extended-spectrum AmpC beta-lactamase, was identified in an Acinetobacter baumannii clinical isolate and was shown to confer resistance to cefepime through hydrolysis.
Extended-spectrum AmpC cephalosporinase in Acinetobacter baumannii: ADC-56 confers resistance to cefepime.
Extended-spectrum AmpC cephalosporinase in Acinetobacter baumannii: ADC-56 confers resistance to cefepime.
Extended-spectrum AmpC cephalosporinase in Acinetobacter baumannii: ADC-56 confers resistance to cefepime.
Extended-spectrum AmpC cephalosporinase in Acinetobacter baumannii: ADC-56 confers resistance to cefepime.
Extended-spectrum AmpC cephalosporinase in Acinetobacter baumannii: ADC-56 confers resistance to cefepime.
Extended-spectrum AmpC cephalosporinase in Acinetobacter baumannii: ADC-56 confers resistance to cefepime.
Extended-spectrum AmpC cephalosporinase in Acinetobacter baumannii: ADC-56 confers resistance to cefepime.
Extended-spectrum AmpC cephalosporinase in Acinetobacter baumannii: ADC-56 confers resistance to cefepime.
Extended-spectrum AmpC cephalosporinase in Acinetobacter baumannii: ADC-56 confers resistance to cefepime.
Genomic analysis of the multidrug-resistant Acinetobacter baumannii strain MDR-ZJ06 widely spread in China.
The study identifies several AMR genes and mutations in the multidrug-resistant Acinetobacter baumannii strain MDR-ZJ06, including bla oxa-23, armA, and various efflux pumps, contributing to resistance against multiple antibiotics.
Complete genome sequence of multidrug-resistant Acinetobacter baumannii strain 1656-2, which forms sturdy biofilm.
Complete genome sequence of multidrug-resistant Acinetobacter baumannii strain 1656-2, which forms sturdy biofilm.
Genome sequence of Acinetobacter baumannii TYTH-1.
Genome sequence of Acinetobacter baumannii TYTH-1.
Draft Genome Sequences of Two Multidrug-Resistant Acinetobacter baumannii Strains of Sequence Type ST92 and ST96.
Complete genome analysis of three Acinetobacter baumannii clinical isolates in China for insight into the diversification of drug resistance elements.
The study identifies multiple AMR genes and resistance islands in three multidrug-resistant Acinetobacter baumannii isolates, highlighting the role of genomic plasticity in the dissemination of resistance mechanisms.
Complete genome analysis of three Acinetobacter baumannii clinical isolates in China for insight into the diversification of drug resistance elements.
The study identifies multiple AMR genes and resistance islands in three multidrug-resistant Acinetobacter baumannii isolates, highlighting the role of genomic plasticity in the dissemination of resistance mechanisms.
DNA microarray for genotyping antibiotic resistance determinants in Acinetobacter baumannii clinical isolates.
The study developed a DNA microarray for genotyping antibiotic resistance determinants in Acinetobacter baumannii clinical isolates, identifying numerous resistance genes and mutations associated with carbapenem, aminoglycoside, fluoroquinolone, and other antibiotic resistances.
Imipenem-resistant Acinetobacter baumannii carrying the ISAba1-bla OXA-23,51 and ISAba1-bla ADC-7 genes in Monteria, Colombia.
The study identified the presence of bla OXA-23, bla OXA-51, and bla ADC-7 genes in imipenem-resistant Acinetobacter baumannii isolates from Colombia, along with the insertion sequence ISAba1 upstream of these genes, contributing to carbapenem resistance.
First report of NDM-1-producing Acinetobacter baumannii in East Africa.
The study reports the first identification of NDM-1-producing Acinetobacter baumannii in East Africa, highlighting the presence of various resistance genes including bla(NDM-1), bla(OXA-23), bla(OXA-51-like), bla(ADC), armA, aadB, aac(6')-Ib, and aph(3')-VI.
First report of NDM-1-producing Acinetobacter baumannii in East Africa.
The study reports the first identification of NDM-1-producing Acinetobacter baumannii in East Africa, highlighting the presence of various resistance genes including bla(NDM-1), bla(OXA-23), bla(OXA-51-like), bla(ADC), armA, aadB, aac(6')-Ib, and aph(3')-VI.
First report of NDM-1-producing Acinetobacter baumannii in East Africa.
First report of NDM-1-producing Acinetobacter baumannii in East Africa.
Emergence of NDM-producing non-baumannii Acinetobacter spp. isolated from China.
The study reports the emergence of NDM-1-producing non-baumannii Acinetobacter spp., including A. nosocomialis and A. pittii, in China. It identifies novel bla ADC genes (bla ADC-69, bla ADC-70, and bla ADC-71) and confirms the presence of bla NDM-1 on a plasmid.
Emergence of NDM-producing non-baumannii Acinetobacter spp. isolated from China.
The study reports the emergence of NDM-1-producing non-baumannii Acinetobacter spp., including A. nosocomialis and A. pittii, in China. It identifies novel bla ADC genes (bla ADC-69, bla ADC-70, and bla ADC-71) and confirms the presence of bla NDM-1 on a plasmid.
Emergence of NDM-producing non-baumannii Acinetobacter spp. isolated from China.
The study reports the emergence of NDM-1-producing non-baumannii Acinetobacter spp., including A. nosocomialis and A. pittii, in China. It identifies novel bla ADC genes (bla ADC-69, bla ADC-70, and bla ADC-71) and confirms the presence of bla NDM-1 on a plasmid.
Antibiotic resistance determinants of a group of multidrug-resistant Acinetobacter baumannii in China.
The study identifies a novel variant of the blaADC gene, blaADC-67, which is prevalent in all 19 multidrug-resistant A. baumannii isolates and confers resistance to beta-lactam antibiotics. Additionally, mutations in the QRDR of gyrA (Ser83Leu) and parC (Ser80Leu) contribute to quinolone resistance.
Structure of ADC-68, a novel carbapenem-hydrolyzing class C extended-spectrum β-lactamase isolated from Acinetobacter baumannii.
Structure of ADC-68, a novel carbapenem-hydrolyzing class C extended-spectrum β-lactamase isolated from Acinetobacter baumannii.
Biochemical and structural analysis of inhibitors targeting the ADC-7 cephalosporinase of Acinetobacter baumannii.
The study characterizes ADC-7, a chromosomal cephalosporinase from Acinetobacter baumannii, and identifies two boronic acid transition state inhibitors (S02030 and SM23) that effectively inhibit ADC-7, demonstrating high binding affinity and synergy with β-lactams to overcome resistance.
Effect of asparagine substitutions in the YXN loop of a class C beta-lactamase of Acinetobacter baumannii on substrate and inhibitor kinetics.
Activities of ceftazidime, ceftaroline, and aztreonam alone and combined with avibactam against isogenic Escherichia coli strains expressing selected single beta-lactamases.
The study characterizes the activity of ceftazidime, ceftaroline, and aztreonam in combination with avibactam against isogenic E. coli strains expressing various beta-lactamase genes, demonstrating that avibactam effectively restores the activity of these β-lactams against strains producing class A, C, and D beta-lactamases.
A novel variant of the β-lactamase ADC-61 gene in multi-drug resistant Acinetobacter baumannii.
A novel variant of the β-lactamase ADC-61 gene in multi-drug resistant Acinetobacter baumannii.
A novel method of consensus pan-chromosome assembly and large-scale comparative analysis reveal the highly flexible pan-genome of Acinetobacter baumannii.
A novel method of consensus pan-chromosome assembly and large-scale comparative analysis reveal the highly flexible pan-genome of Acinetobacter baumannii.
Novel Aminoglycoside Resistance Transposons and Transposon-Derived Circular Forms Detected in Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates.
The study identified various aminoglycoside resistance genes and novel transposons, including Tn6279, ΔTn6279, and Tn1548-like structures, contributing to the resistance of carbapenem-resistant Acinetobacter baumannii isolates.
Novel Aminoglycoside Resistance Transposons and Transposon-Derived Circular Forms Detected in Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates.
Novel Aminoglycoside Resistance Transposons and Transposon-Derived Circular Forms Detected in Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates.
Novel Aminoglycoside Resistance Transposons and Transposon-Derived Circular Forms Detected in Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates.
Novel Aminoglycoside Resistance Transposons and Transposon-Derived Circular Forms Detected in Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates.
Novel Aminoglycoside Resistance Transposons and Transposon-Derived Circular Forms Detected in Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates.
Novel Aminoglycoside Resistance Transposons and Transposon-Derived Circular Forms Detected in Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates.
Novel Aminoglycoside Resistance Transposons and Transposon-Derived Circular Forms Detected in Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates.
Novel Aminoglycoside Resistance Transposons and Transposon-Derived Circular Forms Detected in Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates.
Novel Aminoglycoside Resistance Transposons and Transposon-Derived Circular Forms Detected in Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates.
Novel Aminoglycoside Resistance Transposons and Transposon-Derived Circular Forms Detected in Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates.
Novel Aminoglycoside Resistance Transposons and Transposon-Derived Circular Forms Detected in Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates.
Novel Aminoglycoside Resistance Transposons and Transposon-Derived Circular Forms Detected in Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates.
Novel Aminoglycoside Resistance Transposons and Transposon-Derived Circular Forms Detected in Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates.
Novel Aminoglycoside Resistance Transposons and Transposon-Derived Circular Forms Detected in Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates.
First Occurrence of OXA-72-Producing Acinetobacter baumannii in Serbia.
The study reports the first occurrence of OXA-72-producing Acinetobacter baumannii in Serbia, highlighting the presence of multiple AMR genes including blaOXA-72, aadA2, strA, strB, aphA6, armA, blaADC-25, and blaOXA-66, along with fluoroquinolone resistance mutations in gyrA, parC, and parE.
Co-existence of bla(OXA-23) and bla(NDM-1) genes of Acinetobacter baumannii isolated from Nepal: antimicrobial resistance and clinical significance.
The study identified the coexistence of bla(OXA-23) and bla(NDM-1) genes in Acinetobacter baumannii isolates from Nepal, highlighting their role in carbapenem resistance. Additionally, blaADC and aphA6 genes were detected, contributing to cephalosporin and aminoglycoside resistance, respectively.
Detection of ISAba1 in association with a novel allelic variant of the β-lactamase ADC-82 and class D β-lactamase genes mediating carbapenem resistance among the clinical isolates of MDR A. baumannii.
Detection of ISAba1 in association with a novel allelic variant of the β-lactamase ADC-82 and class D β-lactamase genes mediating carbapenem resistance among the clinical isolates of MDR A. baumannii.
Quantitative assessment of insertion sequence impact on bacterial genome architecture.
The study characterizes the impact of insertion sequences (IS) on the genome architecture of Acinetobacter baumannii and Klebsiella pneumoniae, highlighting the role of IS elements in the mobilization and overexpression of beta-lactamase genes such as blaADC and blaOXA-51-like, contributing to antimicrobial resistance.
Structure-Based Analysis of Boronic Acids as Inhibitors of Acinetobacter-Derived Cephalosporinase-7, a Unique Class C beta-lactamase.
The study characterizes the inhibition of ADC-7, a class C beta-lactamase from Acinetobacter baumannii, by boronic acid transition state analog inhibitors (BATSIs). Several BATSIs, particularly CR192, show potent inhibition of ADC-7, with CR192 exhibiting subnanomolar K_i values. The study identifies critical interactions between BATSIs and ADC-7, including the unique interaction between the trifluoromethyl group of CR192 and Arg340.
Molecular characterization of beta-lactamase genes in clinical isolates of carbapenem-resistant Acinetobacter baumannii.
The study identified multiple beta-lactamase genes, including bla OXA-23-like, bla OXA-40-like, bla OXA-51-like, bla TEM, bla SHV, bla ampC, and bla ADC-7, in carbapenem-resistant Acinetobacter baumannii isolates. These genes contribute to resistance against carbapenems and other β-lactam antibiotics.
Distribution and Molecular Characterization of Acinetobacter baumannii International Clone II Lineage in Japan.
The study identified carbapenem resistance genes such as bla OXA-23-like, bla OXA-51-like, and bla IMP in Acinetobacter baumannii isolates, along with the bla ADC gene associated with cephalosporin resistance. These genes were found in different sequence types of A. baumannii, contributing to varying levels of antimicrobial resistance.
Distribution and Molecular Characterization of Acinetobacter baumannii International Clone II Lineage in Japan.
Distribution and Molecular Characterization of Acinetobacter baumannii International Clone II Lineage in Japan.
Strategic Approaches to Overcome Resistance against Gram-Negative Pathogens Using beta-lactamase Inhibitors and β-Lactam Enhancers: Activity of Three Novel Diazabicyclooctanes WCK 5153, Zidebactam (WCK 5107), and WCK 4234.
The study characterizes three novel diazabicyclooctanes (WCK 5153, zidebactam, and WCK 4234) as potent beta-lactamase inhibitors effective against various beta-lactamases, including KPC-2, OXA-23, OXA-24/40, OXA-48, ADC-7, and PDC-3. These compounds restore susceptibility of multidrug-resistant Gram-negative pathogens to β-lactam antibiotics.
Genomic characterization of extensively drug-resistant Acinetobacter baumannii strain, KAB03 belonging to ST451 from Korea.
Genomic characterization of extensively drug-resistant Acinetobacter baumannii strain, KAB03 belonging to ST451 from Korea.
Co-production of AmpC and extended spectrum beta-lactamases in cephalosporin-resistant Acinetobacter baumannii in Egypt.
The study identifies the prevalence of extended-spectrum beta-lactamases (ESBLs) and AmpC beta-lactamases in cephalosporin-resistant Acinetobacter baumannii isolates in Egypt, highlighting the co-production of blaTEM, blaPER, blaSHV, blaVEB, and blaADC genes contributing to beta-lactam resistance.
Extended Spectrum Beta-Lactamase-Producing Gram-Negative Bacteria Recovered From an Amazonian Lake Near the City of Belém, Brazil.
The study identified various extended-spectrum beta-lactamase (ESBL) genes, including bla CTX-M-15, bla CTX-M-14, bla CTX-M-2, bla TEM, and bla SHV, in multidrug-resistant gram-negative bacteria from an Amazonian lake. These genes were associated with resistance to cephalosporins and other beta-lactam antibiotics.
Extended Spectrum Beta-Lactamase-Producing Gram-Negative Bacteria Recovered From an Amazonian Lake Near the City of Belém, Brazil.
The study identified various extended-spectrum beta-lactamase (ESBL) genes, including bla CTX-M-15, bla CTX-M-14, bla CTX-M-2, bla TEM, and bla SHV, in multidrug-resistant gram-negative bacteria from an Amazonian lake. These genes were associated with resistance to cephalosporins and other beta-lactam antibiotics.
Phenotypic and Genotypic Characterization of Acinetobacter spp. Panel Strains: A Cornerstone to Facilitate Antimicrobial Development.
The study characterized various AMR genes in Acinetobacter spp. including blaPER-1, blaTEM-1D, blaADC-31, blaOXA-82, aac(3')-Ia, aac(6')-Il, aph(3')-Ic, strAB, and others. Mutations in gyrA and parC were associated with fluoroquinolone resistance. Overexpression of efflux pumps like adeB and adeJ contributed to multidrug resistance.
Phenotypic and Genotypic Characterization of Acinetobacter spp. Panel Strains: A Cornerstone to Facilitate Antimicrobial Development.
The study characterized various AMR genes in Acinetobacter spp. including blaPER-1, blaTEM-1D, blaADC-31, blaOXA-82, aac(3')-Ia, aac(6')-Il, aph(3')-Ic, strAB, and others. Mutations in gyrA and parC were associated with fluoroquinolone resistance. Overexpression of efflux pumps like adeB and adeJ contributed to multidrug resistance.
Phenotypic and Genotypic Characterization of Acinetobacter spp. Panel Strains: A Cornerstone to Facilitate Antimicrobial Development.
The study characterized various AMR genes in Acinetobacter spp. including blaPER-1, blaTEM-1D, blaADC-31, blaOXA-82, aac(3')-Ia, aac(6')-Il, aph(3')-Ic, strAB, and others. Mutations in gyrA and parC were associated with fluoroquinolone resistance. Overexpression of efflux pumps like adeB and adeJ contributed to multidrug resistance.
Phenotypic and Genotypic Characterization of Acinetobacter spp. Panel Strains: A Cornerstone to Facilitate Antimicrobial Development.
The study characterized various AMR genes in Acinetobacter spp. including blaPER-1, blaTEM-1D, blaADC-31, blaOXA-82, aac(3')-Ia, aac(6')-Il, aph(3')-Ic, strAB, and others. Mutations in gyrA and parC were associated with fluoroquinolone resistance. Overexpression of efflux pumps like adeB and adeJ contributed to multidrug resistance.
Phenotypic and Genotypic Characterization of Acinetobacter spp. Panel Strains: A Cornerstone to Facilitate Antimicrobial Development.
The study characterized various AMR genes in Acinetobacter spp. including blaPER-1, blaTEM-1D, blaADC-31, blaOXA-82, aac(3')-Ia, aac(6')-Il, aph(3')-Ic, strAB, and others. Mutations in gyrA and parC were associated with fluoroquinolone resistance. Overexpression of efflux pumps like adeB and adeJ contributed to multidrug resistance.
Phenotypic and Genotypic Characterization of Acinetobacter spp. Panel Strains: A Cornerstone to Facilitate Antimicrobial Development.
The study characterized various AMR genes in Acinetobacter spp. including blaPER-1, blaTEM-1D, blaADC-31, blaOXA-82, aac(3')-Ia, aac(6')-Il, aph(3')-Ic, strAB, and others. Mutations in gyrA and parC were associated with fluoroquinolone resistance. Overexpression of efflux pumps like adeB and adeJ contributed to multidrug resistance.
Comparative genomic analysis and multi-drug resistance differences of Acinetobacter baumannii in Chongqing, China.
The study identified 19 drug resistance genes in 10 multidrug-resistant Acinetobacter baumannii strains, with efflux pump genes being the most prevalent. Key genes included aacA4, which had a 19-bp deletion associated with aminoglycoside resistance, and other genes like TEM-1, OXA-23, and ANT(3'')-IIa.
Characterization of an Environmental Multidrug-Resistant Acinetobacter seifertii and Comparative Genomic Analysis Reveals Co-occurrence of Antimicrobial Resistance and Metal Tolerance Determinants.
The study characterizes an environmental multidrug-resistant Acinetobacter seifertii isolate (SAb133) and identifies multiple antimicrobial resistance genes, metal tolerance genes, and virulence factors. Key findings include the presence of bla ADC–25, bla TEM, and various efflux pump genes, along with metal tolerance genes and virulence factors.
Characterization of Beta-Lactamases in Bloodstream-Infection Escherichia coli: Dissemination of bla(ADC) (-) (162) and bla(CMY-) (2) Among Bacteria via an IncF Plasmid.
The study characterizes beta-lactamase genes in bloodstream-infection Escherichia coli, identifying blaTEM-1, blaCTX-M-14, blaCTX-M-27, blaCTX-M-55, blaCTX-M-65, blaOXA-30, blaCMY-2, and blaADC-162 as prevalent. These genes were found to be disseminated via IncF plasmids, highlighting their role in multidrug resistance.
Human pleural fluid triggers global changes in the transcriptional landscape of Acinetobacter baumannii as an adaptive response to stress.
The study identifies that human pleural fluid (PF) induces changes in the transcriptional landscape of Acinetobacter baumannii, affecting genes related to motility, biofilm formation, efflux pumps, and antibiotic resistance. Specifically, PF leads to reduced expression of beta-lactamase genes (carO, blaADC-99, blaOXA-89) and altered susceptibility to several antibiotics.
Whole-Genome-Sequence-Based Characterization of Extensively Drug-Resistant Acinetobacter baumannii Hospital Outbreak.
The study identified two extensively drug-resistant Acinetobacter baumannii clones carrying blaOXA-23 and blaOXA-72, which confer resistance to carbapenems. Additional resistance genes such as aac(3')-Ia, ant(3'')-Ia, aph(3')-VIa, strA, strB, armA, blaADC-73, blaADC-74, blaTEM-1D, mph(E), and msr(E) were also detected.
Whole-Genome-Sequence-Based Characterization of Extensively Drug-Resistant Acinetobacter baumannii Hospital Outbreak.
The study identified two extensively drug-resistant Acinetobacter baumannii clones carrying blaOXA-23 and blaOXA-72, which confer resistance to carbapenems. Additional resistance genes such as aac(3')-Ia, ant(3'')-Ia, aph(3')-VIa, strA, strB, armA, blaADC-73, blaADC-74, blaTEM-1D, mph(E), and msr(E) were also detected.
In Vitro Activity of Sulbactam-Durlobactam against Acinetobacter baumannii-calcoaceticus Complex Isolates Collected Globally in 2016 and 2017.
In Vitro Activity of Sulbactam-Durlobactam against Acinetobacter baumannii-calcoaceticus Complex Isolates Collected Globally in 2016 and 2017.
Oral colonisation by antimicrobial-resistant Gram-negative bacteria among long-term care facility residents: prevalence, risk factors, and molecular epidemiology.
The study identified several AMR genes in Gram-negative bacteria isolated from LTCF residents, including bla CTX-M-27, bla CTX-M-14, bla TEM-1B, bla IMP-1, and others, which confer resistance to various antibiotics such as β-lactams, aminoglycosides, and fluoroquinolones.
Acquisition of plasmids conferring carbapenem and aminoglycoside resistance and loss of surface-exposed macromolecule structures as strategies for the adaptation of Acinetobacter baumannii CC104(O)/CC15(P) strains to the clinical setting.
The study identifies the blaOXA-58 gene on a plasmid as a key contributor to carbapenem resistance in Acinetobacter baumannii CC104(O)/CC15(P) strains, along with the loss of surface-exposed macromolecules aiding in clinical adaptation.
1,2,3-Triazolylmethaneboronate: A Structure Activity Relationship Study of a Class of beta-lactamase Inhibitors against Acinetobacter baumannii Cephalosporinase.
The study identifies ADC-7 as a beta-lactamase from Acinetobacter baumannii and characterizes a series of α-triazolylmethaneboronic acid inhibitors that effectively inhibit ADC-7, thereby restoring the activity of ceftazidime against bacteria expressing this enzyme.
Comparative Genomics of Acinetobacter baumannii Clinical Strains From Brazil Reveals Polyclonal Dissemination and Selective Exchange of Mobile Genetic Elements Associated With Resistance Genes.
The study identifies multiple beta-lactamase genes, including blaTEM-1, blaADC-182, and blaOXA-253, as well as aminoglycoside resistance genes such as aph3 and aadB, which contribute to the multidrug resistance profile of Acinetobacter baumannii clinical strains in Brazil.
What do we know about plasmids carried by members of the Acinetobacter genus?
The paper reviews the diversity and characteristics of plasmids in Acinetobacter species, particularly highlighting the presence of various beta-lactamase genes (blaOXA-23, blaOXA-58, blaOXA-24, blaPER-1, blaADC-25), aminoglycoside resistance genes (aadB, aphA6), tetracycline resistance gene (tet(39)), macrolide resistance genes (mph(E), msr(E)), sulfonamide resistance gene (sul2), and other resistance genes (bcr). These genes are primarily found on plasmids and contribute to multidrug resistance in clinical isolates.
Structural Insights into Inhibition of the Acinetobacter-Derived Cephalosporinase ADC-7 by Ceftazidime and Its Boronic Acid Transition State Analog.
The study characterizes the inhibition of the Acinetobacter-derived cephalosporinase ADC-7 by ceftazidime and its boronic acid transition state analog, LP06, providing structural insights into the mechanism of action and potential for inhibitor design.
Genomic analysis reveals high virulence and antibiotic resistance amongst phage susceptible Acinetobacter baumannii.
The study identified multiple antibiotic resistance genes in phage-susceptible Acinetobacter baumannii strains, including sulfonamide, tetracycline, beta-lactam, aminoglycoside, macrolide, and phenicol resistance genes. These findings highlight the complex resistance profiles of these strains and their potential implications for therapeutic strategies.
A comprehensive and contemporary "snapshot" of beta-lactamases in carbapenem resistant Acinetobacter baumannii.
The study identifies several beta-lactamase alleles, including blaOXA-23, blaOXA-82, blaOXA-172, blaOXA-72, blaADC-30, blaADC-162, and blaADC-212, which are associated with carbapenem resistance in Acinetobacter baumannii. These genes were found in a large number of isolates and highlight the diversity of resistance mechanisms.
A comprehensive and contemporary "snapshot" of beta-lactamases in carbapenem resistant Acinetobacter baumannii.
The study identifies several beta-lactamase alleles, including blaOXA-23, blaOXA-82, blaOXA-172, blaOXA-72, blaADC-30, blaADC-162, and blaADC-212, which are associated with carbapenem resistance in Acinetobacter baumannii. These genes were found in a large number of isolates and highlight the diversity of resistance mechanisms.
A comprehensive and contemporary "snapshot" of beta-lactamases in carbapenem resistant Acinetobacter baumannii.
The study identifies several beta-lactamase alleles, including blaOXA-23, blaOXA-82, blaOXA-172, blaOXA-72, blaADC-30, blaADC-162, and blaADC-212, which are associated with carbapenem resistance in Acinetobacter baumannii. These genes were found in a large number of isolates and highlight the diversity of resistance mechanisms.
A Biological Inventory of Prophages in A. baumannii Genomes Reveal Distinct Distributions in Classes, Length, and Genomic Positions.
The study identifies several antimicrobial resistance (AMR) genes encoded in prophages within Acinetobacter baumannii genomes, including blaOXA-23, blaNDM-1, blaADC-5, blaOXA-67, blaOXA-115, blaTEM-12, aac(3)-I, aac(3)-Id, aacA16, aph(3')-Ia, aph(3')-VI, aph(6)-Id, aph(3'')-Ib, msr(E), mph(E), and sul2. These genes confer resistance to various antibiotics such as carbapenems, penicillins, cephalosporins, monobactams, aminoglycosides, macrolides, and sulfonamides.
Acinetobacter baumannii Antibiotic Resistance Mechanisms.
The paper reviews various beta-lactamases and other resistance mechanisms in Acinetobacter baumannii, focusing on their roles in resistance to beta-lactams, aminoglycosides, and other antibiotics.
Acinetobacter baumannii Antibiotic Resistance Mechanisms.
The paper reviews various beta-lactamases and other resistance mechanisms in Acinetobacter baumannii, focusing on their roles in resistance to beta-lactams, aminoglycosides, and other antibiotics.
Acinetobacter baumannii Antibiotic Resistance Mechanisms.
The paper reviews various beta-lactamases and other resistance mechanisms in Acinetobacter baumannii, focusing on their roles in resistance to beta-lactams, aminoglycosides, and other antibiotics.
Acinetobacter baumannii Antibiotic Resistance Mechanisms.
The paper reviews various beta-lactamases and other resistance mechanisms in Acinetobacter baumannii, focusing on their roles in resistance to beta-lactams, aminoglycosides, and other antibiotics.
Acinetobacter baumannii Antibiotic Resistance Mechanisms.
The paper reviews various beta-lactamases and other resistance mechanisms in Acinetobacter baumannii, focusing on their roles in resistance to beta-lactams, aminoglycosides, and other antibiotics.
Acinetobacter baumannii Antibiotic Resistance Mechanisms.
The paper reviews various beta-lactamases and other resistance mechanisms in Acinetobacter baumannii, focusing on their roles in resistance to beta-lactams, aminoglycosides, and other antibiotics.
Acinetobacter baumannii Antibiotic Resistance Mechanisms.
The paper reviews various beta-lactamases and other resistance mechanisms in Acinetobacter baumannii, focusing on their roles in resistance to beta-lactams, aminoglycosides, and other antibiotics.
Acinetobacter baumannii Antibiotic Resistance Mechanisms.
The paper reviews various beta-lactamases and other resistance mechanisms in Acinetobacter baumannii, focusing on their roles in resistance to beta-lactams, aminoglycosides, and other antibiotics.
Acinetobacter baumannii Antibiotic Resistance Mechanisms.
The paper reviews various beta-lactamases and other resistance mechanisms in Acinetobacter baumannii, focusing on their roles in resistance to beta-lactams, aminoglycosides, and other antibiotics.
Acinetobacter baumannii Antibiotic Resistance Mechanisms.
The paper reviews various beta-lactamases and other resistance mechanisms in Acinetobacter baumannii, focusing on their roles in resistance to beta-lactams, aminoglycosides, and other antibiotics.
Acinetobacter baumannii Antibiotic Resistance Mechanisms.
The paper reviews various beta-lactamases and other resistance mechanisms in Acinetobacter baumannii, focusing on their roles in resistance to beta-lactams, aminoglycosides, and other antibiotics.
Acinetobacter baumannii Antibiotic Resistance Mechanisms.
The paper reviews various beta-lactamases and other resistance mechanisms in Acinetobacter baumannii, focusing on their roles in resistance to beta-lactams, aminoglycosides, and other antibiotics.
Acinetobacter baumannii Antibiotic Resistance Mechanisms.
The paper reviews various beta-lactamases and other resistance mechanisms in Acinetobacter baumannii, focusing on their roles in resistance to beta-lactams, aminoglycosides, and other antibiotics.
Acinetobacter baumannii Antibiotic Resistance Mechanisms.
The paper reviews various beta-lactamases and other resistance mechanisms in Acinetobacter baumannii, focusing on their roles in resistance to beta-lactams, aminoglycosides, and other antibiotics.
Acinetobacter baumannii Antibiotic Resistance Mechanisms.
The paper reviews various beta-lactamases and other resistance mechanisms in Acinetobacter baumannii, focusing on their roles in resistance to beta-lactams, aminoglycosides, and other antibiotics.
Acinetobacter baumannii Antibiotic Resistance Mechanisms.
The paper reviews various beta-lactamases and other resistance mechanisms in Acinetobacter baumannii, focusing on their roles in resistance to beta-lactams, aminoglycosides, and other antibiotics.
Acinetobacter baumannii Antibiotic Resistance Mechanisms.
The paper reviews various beta-lactamases and other resistance mechanisms in Acinetobacter baumannii, focusing on their roles in resistance to beta-lactams, aminoglycosides, and other antibiotics.
Acinetobacter baumannii Antibiotic Resistance Mechanisms.
The paper reviews various beta-lactamases and other resistance mechanisms in Acinetobacter baumannii, focusing on their roles in resistance to beta-lactams, aminoglycosides, and other antibiotics.
Acinetobacter baumannii Antibiotic Resistance Mechanisms.
The paper reviews various beta-lactamases and other resistance mechanisms in Acinetobacter baumannii, focusing on their roles in resistance to beta-lactams, aminoglycosides, and other antibiotics.
Acinetobacter baumannii Antibiotic Resistance Mechanisms.
The paper reviews various beta-lactamases and other resistance mechanisms in Acinetobacter baumannii, focusing on their roles in resistance to beta-lactams, aminoglycosides, and other antibiotics.
Two Acinetobacter baumannii Isolates Obtained From a Fatal Necrotizing Fasciitis Infection Display Distinct Genomic and Phenotypic Characteristics in Comparison to Type Strains.
The study characterizes two XDR Acinetobacter baumannii isolates, NFAb-1 and NFAb-2, obtained from a fatal necrotizing fasciitis case. These isolates exhibit resistance to multiple antibiotics, including carbapenems, aminoglycosides, fluoroquinolones, and others, indicating the presence of various AMR genes such as blaOXA-51-like, blaOXA-23-like, blaOXA-58-like, blaADC, blaNDM, blaKPC, aac(6')-Ib, aadA, ant(3'')-Ia, mph(A), erm(B), tet(A), tet(G), qnrS1, mexAB-oprM, acrAB-tolC, oqxAB, cat, cfr, and optrA.
Antimicrobial Resistance Mechanisms and Virulence of Colistin- and Carbapenem-Resistant Acinetobacter baumannii Isolated from a Teaching Hospital in Taiwan.
The study identifies carbapenem resistance mediated by blaOXA-23 and colistin resistance mediated by mutations in pmrB and lpxD in Acinetobacter baumannii isolates.
Histone-like nucleoid-structuring protein (H-NS) regulatory role in antibiotic resistance in Acinetobacter baumannii.
The study shows that H-NS regulates the expression of antibiotic resistance genes in Acinetobacter baumannii, leading to increased resistance to beta-lactam antibiotics, aminoglycosides, quinolones, chloramphenicol, trimethoprim, sulfonamides, and colistin.
Mouse pneumonia model by Acinetobacter baumannii multidrug resistant strains: Comparison between intranasal inoculation, intratracheal instillation and oropharyngeal aspiration techniques.
The study identified various AMR genes in two multidrug-resistant Acinetobacter baumannii strains, ACC001 and ACC002, including aminoglycoside resistance genes, tetracycline resistance genes, beta-lactamases, and sulfonamide resistance genes. These genes contribute to resistance against multiple antibiotics such as gentamicin, tobramycin, tetracycline, penicillins, cephalosporins, and sulfonamides.
Genomic Characterization of Extensively Drug-Resistant NDM-Producing Acinetobacter baumannii Clinical Isolates With the Emergence of Novel bla (ADC-257).
The study identified several AMR genes, including novel bla ADC-257, and mutations in gyrA and parC associated with fluoroquinolone resistance in extensively drug-resistant NDM-producing Acinetobacter baumannii isolates.
Genotypic and Phenotypic Characterization of Novel Sequence Types of Carbapenem-Resistant Acinetobacter baumannii, With Heterogeneous Resistance Determinants and Targeted Variations in Efflux Operons.
The study identifies various AMR genes and mutations in carbapenem-resistant Acinetobacter baumannii strains, including beta-lactamases, aminoglycoside modifying enzymes, and efflux pumps, contributing to multidrug resistance.
Whole-genome sequencing for the characterization of resistance mechanisms and epidemiology of colistin-resistant Acinetobacter baumannii.
The study identified several beta-lactam resistance genes, including ADC-18, OXA-133, OXA-23, OXA-66, TEM-1, VIM-2, and RND efflux pumps (adeI, adeJ, adeK, adeN) in colistin-resistant Acinetobacter baumannii strains.
Genetic Diversity of Antimicrobial Resistance and Key Virulence Features in Two Extensively Drug-Resistant Acinetobacter baumannii Isolates.
The study identified various AMR genes in two extensively drug-resistant A. baumannii isolates, including aminoglycoside resistance genes, sulfonamide resistance genes, beta-lactamase genes, and efflux pump genes, highlighting the complexity of their resistance mechanisms.
Genetic Diversity of Antimicrobial Resistance and Key Virulence Features in Two Extensively Drug-Resistant Acinetobacter baumannii Isolates.
The study identified various AMR genes in two extensively drug-resistant A. baumannii isolates, including aminoglycoside resistance genes, sulfonamide resistance genes, beta-lactamase genes, and efflux pump genes, highlighting the complexity of their resistance mechanisms.
Class C beta-lactamases: Molecular Characteristics.
The paper characterizes various class C beta-lactamases, highlighting their molecular characteristics, resistance profiles, and genetic variations. Key findings include the identification of specific genes such as blaACC-1, blaACT-1, blaADC-1, blaCMY-2, blaFOX-1, blaMOX-1, and blaPDC-1, along with their roles in conferring resistance to various β-lactam antibiotics.
In vitro activity of sulbactam-durlobactam against carbapenem-resistant Acinetobacter baumannii and mechanisms of resistance.
SUL-DUR exhibited excellent in vitro antibacterial activity against carbapenemase-producing A. baumannii isolates. Mechanisms of resistance included PBP substitutions and the production of specific beta-lactamases.
In vitro activity of sulbactam-durlobactam against carbapenem-resistant Acinetobacter baumannii and mechanisms of resistance.
SUL-DUR exhibited excellent in vitro antibacterial activity against carbapenemase-producing A. baumannii isolates. Mechanisms of resistance included PBP substitutions and the production of specific beta-lactamases.
In vitro activity of sulbactam-durlobactam against carbapenem-resistant Acinetobacter baumannii and mechanisms of resistance.
SUL-DUR exhibited excellent in vitro antibacterial activity against carbapenemase-producing A. baumannii isolates. Mechanisms of resistance included PBP substitutions and the production of specific beta-lactamases.
In vitro activity of sulbactam-durlobactam against carbapenem-resistant Acinetobacter baumannii and mechanisms of resistance.
SUL-DUR exhibited excellent in vitro antibacterial activity against carbapenemase-producing A. baumannii isolates. Mechanisms of resistance included PBP substitutions and the production of specific beta-lactamases.
In vitro activity of sulbactam-durlobactam against carbapenem-resistant Acinetobacter baumannii and mechanisms of resistance.
SUL-DUR exhibited excellent in vitro antibacterial activity against carbapenemase-producing A. baumannii isolates. Mechanisms of resistance included PBP substitutions and the production of specific beta-lactamases.
In vitro activity of sulbactam-durlobactam against carbapenem-resistant Acinetobacter baumannii and mechanisms of resistance.
SUL-DUR exhibited excellent in vitro antibacterial activity against carbapenemase-producing A. baumannii isolates. Mechanisms of resistance included PBP substitutions and the production of specific beta-lactamases.
In vitro activity of sulbactam-durlobactam against carbapenem-resistant Acinetobacter baumannii and mechanisms of resistance.
SUL-DUR exhibited excellent in vitro antibacterial activity against carbapenemase-producing A. baumannii isolates. Mechanisms of resistance included PBP substitutions and the production of specific beta-lactamases.
In vitro activity of sulbactam-durlobactam against carbapenem-resistant Acinetobacter baumannii and mechanisms of resistance.
SUL-DUR exhibited excellent in vitro antibacterial activity against carbapenemase-producing A. baumannii isolates. Mechanisms of resistance included PBP substitutions and the production of specific beta-lactamases.
Insights into mobile genetic elements and the role of conjugative plasmid in transferring aminoglycoside resistance in extensively drug-resistant Acinetobacter baumannii AB329.
The study identified several AMR genes in the extensively drug-resistant Acinetobacter baumannii AB329, including beta-lactamases (blaOXA-51, blaADC-25, blaOXA-23, blaTEM-1D), aminoglycoside resistance genes (aph(3')-Ia, aph(3'')-Ib, aph(6)-Id, armA), tetracycline resistance genes (tet(B), tet(R)), and macrolide resistance genes (mph(E), msr(E)). Additionally, the aminoglycoside resistance gene aph(3')-VIa was found on the conjugative plasmid pAB329b, which was shown to transfer resistance to sodium azide-resistant A. baumannii.
Metagenomic features of bioburden serve as outcome indicators in combat extremity wounds.
The study identifies several AMR genes, including beta-lactamases blaADC-10 and blaADC-25, aminoglycoside phosphotransferase aphA-3, and beta-lactamase blaOXA-50, associated with resistance to beta-lactam and aminoglycoside antibiotics in combat wound bioburden.
Metagenomic features of bioburden serve as outcome indicators in combat extremity wounds.
The study identifies several AMR genes, including beta-lactamases blaADC-10 and blaADC-25, aminoglycoside phosphotransferase aphA-3, and beta-lactamase blaOXA-50, associated with resistance to beta-lactam and aminoglycoside antibiotics in combat wound bioburden.
In Vitro Activity of Sulbactam-Durlobactam against Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates: A Multicentre Report from Italy.
The study evaluated the in vitro activity of sulbactam-durlobactam (SUL-DUR) against 141 carbapenem-resistant A. baumannii isolates. It identified several resistance genes including blaOXA-20, blaOXA-58, blaOXA-66, blaADC-25, aac(6')-Ib3, aac(6')-Ib-cr, and mutations in gyrA (S81L) and parC (V104I, D105E). Additionally, mutations in PBP3 (Q488K and Y528H) were found in SUL-DUR resistant isolates.
Validation and Application of Long-Read Whole-Genome Sequencing for Antimicrobial Resistance Gene Detection and Antimicrobial Susceptibility Testing.
The study validated the use of long-read whole-genome sequencing for detecting antimicrobial resistance genes and predicting antimicrobial susceptibility. Several beta-lactamase and carbapenemase genes were identified in various bacterial isolates, demonstrating their role in resistance to specific antibiotics.
Detection and homology analysis of carbapenem resistant Acinetobacter baumannii resistance gene.
The study identified several carbapenem resistance genes in Acinetobacter baumannii, including adc, oxa-51, oxa-23, qace delta 1-sull, intl1, ant (3")-i, aac (3")-i, and tem. These genes contribute to resistance against various antibiotics, particularly carbapenems and beta-lactams.
Genomic Characterization of Carbapenem-Resistant Acinetobacter baumannii (CRAB) in Mechanically Ventilated COVID-19 Patients and Impact of Infection Control Measures on Reducing CRAB Circulation during the Second Wave of the SARS-CoV-2 Pandemic in Milan, Italy.
The study identified various AMR genes in CRAB isolates, including blaOXA-23, aph(3''-Ib, aph(6)-Id, abeM, mexT, abeS, tetA, adeABC, adeJKL, OXA-66, ADC-73, OXA-127, and ADC-30, which contribute to resistance against carbapenems, aminoglycosides, fluoroquinolones, macrolides, tetracyclines, and multiple antibiotics.
Genomic Characterization of Carbapenem-Resistant Acinetobacter baumannii (CRAB) in Mechanically Ventilated COVID-19 Patients and Impact of Infection Control Measures on Reducing CRAB Circulation during the Second Wave of the SARS-CoV-2 Pandemic in Milan, Italy.
The study identified various AMR genes in CRAB isolates, including blaOXA-23, aph(3''-Ib, aph(6)-Id, abeM, mexT, abeS, tetA, adeABC, adeJKL, OXA-66, ADC-73, OXA-127, and ADC-30, which contribute to resistance against carbapenems, aminoglycosides, fluoroquinolones, macrolides, tetracyclines, and multiple antibiotics.
Genomic Diversity, Antimicrobial Susceptibility, and Biofilm Formation of Clinical Acinetobacter baumannii Isolates from Horses.
The study identified multiple AMR genes in equine Acinetobacter baumannii isolates, including beta-lactamases (bla OXA-51-like, bla ADC-25, bla TEM-1D), sulfonamide resistance genes (sul1, sul2), chloramphenicol resistance genes (catA1, ABUW 0982), tetracycline resistance genes (tet(A), tet(B), tet(39)), and aminoglycoside modifying enzymes (aph(3′)-Ia, aph(3`)-Ic, aph(6)-Id, aac(3)-Ia). Additionally, eight novel OXA-51-like variants (OXA-970 to OXA-977) were characterized.
Sulfonamidoboronic Acids as "Cross-Class" Inhibitors of an Expanded-Spectrum Class C Cephalosporinase, ADC-33, and a Class D Carbapenemase, OXA-24/40: Strategic Compound Design to Combat Resistance in Acinetobacter baumannii.
CR167 and its chiral analogue 6b were identified as effective inhibitors of the class C beta-lactamase ADC-33 and the class D beta-lactamase OXA-24/40, demonstrating cross-class inhibition against multiple beta-lactamase classes in Acinetobacter baumannii.
Sulfonamidoboronic Acids as "Cross-Class" Inhibitors of an Expanded-Spectrum Class C Cephalosporinase, ADC-33, and a Class D Carbapenemase, OXA-24/40: Strategic Compound Design to Combat Resistance in Acinetobacter baumannii.
CR167 and its chiral analogue 6b were identified as effective inhibitors of the class C beta-lactamase ADC-33 and the class D beta-lactamase OXA-24/40, demonstrating cross-class inhibition against multiple beta-lactamase classes in Acinetobacter baumannii.
Sulfonamidoboronic Acids as "Cross-Class" Inhibitors of an Expanded-Spectrum Class C Cephalosporinase, ADC-33, and a Class D Carbapenemase, OXA-24/40: Strategic Compound Design to Combat Resistance in Acinetobacter baumannii.
CR167 and its chiral analogue 6b were identified as effective inhibitors of the class C beta-lactamase ADC-33 and the class D beta-lactamase OXA-24/40, demonstrating cross-class inhibition against multiple beta-lactamase classes in Acinetobacter baumannii.
A novel strategy to characterize the pattern of β-lactam antibiotic-induced drug resistance in Acinetobacter baumannii.
The study identifies and characterizes beta-lactamase genes (blaAmpC, blaADC, and blaOXA) in Acinetobacter baumannii, highlighting their differential expression in response to various β-lactam antibiotics.
Antimicrobial resistance and mechanisms of epigenetic regulation.
The paper discusses the role of epigenetic modifications, such as DNA methylation, histone modification, and RNA methylation, in antimicrobial resistance. It highlights how these mechanisms contribute to bacterial adaptation and resistance to antibiotics.
Emergence of ADC-5 Cephalosporinase in environmental Acinetobacter baumannii from a German tank milk with a novel Sequence Type.
The study identifies the first occurrence of the ADC-5 cephalosporinase in an environmental isolate of Acinetobacter baumannii, along with the OXA-408 oxacillinase, which contribute to resistance against ceftazidime and other beta-lactam antibiotics.
Abundance and prevalence of ESBL coding genes in patients undergoing first line eradication therapy for Helicobacter pylori.
The study identified several ESBL coding genes, including bla OXY, bla ADC, bla IMP, bla OXA, bla L1, bla LRA, bla EC, bla ACI, and bla FAR, which were found to be prevalent in patients undergoing H. pylori eradication therapy. The abundance of these genes varied between pre- and post-eradication states.
Co-Existence of bla(NDM-1), bla(OXA-23), bla(OXA-64), bla(PER-7) and bla(ADC-57) in a Clinical Isolate of Acinetobacter baumannii from Alexandria, Egypt.
The study identifies five β-lactamase genes (bla(NDM-1), bla(OXA-23), bla(OXA-64), bla(PER-7), and bla(ADC-57)) in a clinical isolate of Acinetobacter baumannii from Egypt, highlighting the co-existence of multiple carbapenem resistance mechanisms.
Acinetobacter baumannii: A multidrug-resistant pathogen, has emerged in Saudi Arabia.
The study highlights the emergence of multidrug-resistant Acinetobacter baumannii in Saudi Arabia, emphasizing the role of beta-lactamases such as blaOXA-23, blaOXA-24/40, and GES-5 in carbapenem resistance.
Characterization of Carbapenemase- and ESBL-Producing Gram-Negative Bacilli Isolated from Patients with Urinary Tract and Bloodstream Infections.
The study identified multiple carbapenemase and ESBL genes, including bla KPC-2, bla KPC-3, bla NDM, bla CTX-M-15, bla CTX-M-27, bla CTX-M-14, bla SHV-187, bla SHV-12, bla OXA-181, and others, highlighting the diversity of beta-lactam resistance mechanisms in Gram-negative bacteria from urinary tract and bloodstream infections.
The Molecular Characterization of bla(NDM-1)-Positive Acinetobacter baumannii Isolated in Central Greece.
The study identifies multiple AMR genes in blaNDM-1-positive Acinetobacter baumannii isolates, including beta-lactamases, aminoglycoside-modifying enzymes, sulfonamide resistance genes, macrolide resistance genes, tetracycline resistance genes, trimethoprim resistance genes, and quaternary ammonium resistance genes.
Genome sequence of an Acinetobacter pittii strain obtained from a red-lored parrot with pneumonia.
Genome sequence of an Acinetobacter pittii strain obtained from a red-lored parrot with pneumonia.
Evaluation of antimicrobial susceptibility tests for Acinetobacter and Pseudomonas species using disks containing a high dose of meropenem.
The study identified several beta-lactamase genes, including blaIMP-1, blaDIM-1, blaNDM-1, blaVIM-1, blaGES-5, blaOXA-23, blaOXA-51-like, and blaADC, which confer resistance to meropenem in Acinetobacter and Pseudomonas species.
Oligella spp.: A systematic review on an uncommon urinary pathogen.
The study identifies genetic determinants of resistance in Oligella spp., including the chromosomal beta-lactamase gene bla ABA−1 in O. urethralis and the aminoglycoside acetyltransferase gene acc(6')-Ib in O. ureolytica.
A panel of genotypically and phenotypically diverse clinical Acinetobacter baumannii strains for novel antibiotic development.
The study identifies various AMR genes and mutations in a diverse panel of Acinetobacter baumannii strains, including bla OXA-23, bla OXA-24, bla OXA-58, bla NDM-1, and mutations in gyrA and parC associated with fluoroquinolone resistance.
Antimicrobial resistance genes harbored in invasive Acinetobacter calcoaceticus-baumannii complex isolated from Korean children during the pre-COVID-19 pandemic periods, 2015-2020.
The study identified blaOXA23 as the primary carbapenem resistance gene in Acinetobacter baumannii (AB) isolates, along with blaADC, blaOXA51, and various aminoglycoside resistance genes such as aad and armA. Fluoroquinolone resistance was linked to mutations in gyrA and parC. Efflux pumps abe and ade were widespread in AB isolates.
Whole-genome sequencing of two multidrug-resistant acinetobacter baumannii strains isolated from a neonatal intensive care unit in Egypt: a prospective cross-sectional study.
The study identified multidrug-resistant Acinetobacter baumannii strains from a neonatal ICU in Egypt, highlighting the presence of various beta-lactamase genes, aminoglycoside resistance genes, macrolide resistance genes, tetracycline resistance genes, and sulfonamide resistance genes.
Relative inhibitory activities of newly developed diazabicyclooctanes, boronic acid derivatives, and penicillin-based sulfone beta-lactamase inhibitors against broad-spectrum AmpC beta-lactamases.
The study evaluates the inhibitory activities of various beta-lactamase inhibitors against a wide range of AmpC beta-lactamases, identifying the effectiveness of certain inhibitors like durlobactam and zidebactam in reducing the MIC values of β-lactam antibiotics against AmpC-producing strains.
Neural network-based predictions of antimicrobial resistance phenotypes in multidrug-resistant Acinetobacter baumannii from whole genome sequencing and gene expression.
The study presents a deep neural network model capable of predicting antimicrobial resistance phenotypes in multidrug-resistant Acinetobacter baumannii using whole genome sequencing and gene expression data. The model achieves high accuracy in predicting resistance to various antibiotics, including β-lactams, aminoglycosides, and carbapenems.
Genomic insights into drug resistance and virulence determinants in rare pyomelanin-producing clinical isolates of Acinetobacter baumannii.
The study identifies several AMR genes including blaOXA-23, blaADC-25, aph(3')-VIa, armA, aph(6)-Id, tet(B), and msr(E) in pyomelanin-producing Acinetobacter baumannii isolates, highlighting their multidrug-resistant profile.
Carbapenem-induced beta-lactamase-isoform expression trends in Acinetobacter baumannii.
The study identifies and characterizes beta-lactamase isoforms, particularly class C (AmpC and ADC) and class D (OXA), in Acinetobacter baumannii under carbapenem exposure, demonstrating concentration- and carbapenem-dependent expression trends.
Molecular epidemiology of carbapenem-resistant Acinetobacter baumannii group in Taiwan.
The study identifies carbapenem resistance genes such as bla OXA-23-like, bla OXA-24-like, bla OXA-51-like, bla NDM-1, bla OXA-58-like, and bla IMP in Acinetobacter baumannii and non-A. baumannii strains in Taiwan. It highlights the prevalence of these genes and their association with carbapenem resistance.
Molecular Epidemiology and Genetic Characterization of Carbapenem-Resistant Acinetobacter baumannii Isolates from the ICU of a Tertiary Hospital in East China.
The study identified 48 antimicrobial resistance genes (ARGs) in 39 carbapenem-resistant Acinetobacter baumannii (CRAB) isolates, including blaOXA-66, blaOXA-23, blaADC-30, blaADC-73, gyrA, ant(3")-IIa, aph(3")-Ib, aph(6)-Id, tetB, tetR, sul1, sul2, LpsB, LpxC, and LpxA, which confer resistance to various antibiotics such as carbapenems, cephalosporins, fluoroquinolones, aminoglycosides, tetracycline, and sulfonamides.
Molecular Epidemiology and Genetic Characterization of Carbapenem-Resistant Acinetobacter baumannii Isolates from the ICU of a Tertiary Hospital in East China.
The study identified 48 antimicrobial resistance genes (ARGs) in 39 carbapenem-resistant Acinetobacter baumannii (CRAB) isolates, including blaOXA-66, blaOXA-23, blaADC-30, blaADC-73, gyrA, ant(3")-IIa, aph(3")-Ib, aph(6)-Id, tetB, tetR, sul1, sul2, LpsB, LpxC, and LpxA, which confer resistance to various antibiotics such as carbapenems, cephalosporins, fluoroquinolones, aminoglycosides, tetracycline, and sulfonamides.
Proximity-Ligation Metagenomic Sequence Analysis Reveals That the Antibiotic Resistome Makes Significant Transitions During Municipal Wastewater Treatment.
The study reveals significant transitions in the antibiotic resistome during municipal wastewater treatment, highlighting the presence of various ARGs in untreated wastewater and their reduced abundance in treated samples. Notably, certain ARGs like blaOXA, mef(A), and msr(D) were prevalent in untreated wastewater, while others like aph(3")-Ib, aph(6)-Id, mef(C), mph(A), and mph(G) were more prominent in activated sludge samples.
Whole-genome sequencing of Acinetobacter baumannii clinical isolates from a tertiary hospital in Terengganu, Malaysia (2011-2020), revealed the predominance of the Global Clone 2 lineage.
The study identified the predominance of the Global Clone 2 lineage of Acinetobacter baumannii in Terengganu, Malaysia, with a focus on the detection of various antimicrobial resistance genes, including bla OXA-23, bla ADC, bla NDM-1, and others, contributing to multidrug resistance.
beta-lactamase diversity in Acinetobacter baumannii.
The study characterizes the diversity and distribution of beta-lactamase alleles in Acinetobacter baumannii, highlighting the most common intrinsic and acquired alleles such as bla ADC-73, bla ADC-30, bla OXA-66, and bla OXA-23, which are associated with carbapenem resistance.
Comprehensive molecular epidemiology of Acinetobacter baumannii from diverse sources in Nigeria.
The study identified 168 AMR genes in 189 Nigerian A. baumannii isolates, including blaADC-79, blaOXA-23, aph(3")-Ib, and others, highlighting the widespread presence of multidrug resistance.
Evolution of carbapenemase activity in the class C beta-lactamase ADC-1.
The study characterizes the ADC-1 beta-lactamase and its mutant derivatives, highlighting how specific mutations enhance the deacylation of ertapenem, thereby increasing carbapenem resistance.
Evolution of carbapenemase activity in the class C β-lactamase ADC-1.
The study characterizes the ADC-1 beta-lactamase and its mutant derivatives, highlighting how specific mutations enhance the deacylation of ertapenem, thereby increasing carbapenem resistance.
Genomic and phenotypic insights into ST164 bla(NDM-1)-positive Acinetobacter baumannii from intestinal colonization in China.
The study identifies multiple AMR genes, including bla NDM-1, aph(3')-VI, bla ADC-25, bla OXA-23, bla CARB-16, and bla OXA-91, in ST164 bla NDM-1-positive Acinetobacter baumannii isolates from intestinal colonization in China.
AmrProfiler: A Comprehensive Tool for Antimicrobial Resistance Gene Detection and Analysis
AmrProfiler identifies a wide range of AMR genes and mutations across multiple bacterial species, demonstrating high accuracy and broader species coverage compared to existing tools.
In silico and in vitro comparative analysis of 79 Acinetobacter baumannii clinical isolates.
The study identified blaADC-25 as a prevalent cephalosporinase gene in 78 out of 79 A. baumannii isolates, contributing to resistance against multiple beta-lactam antibiotics.
Resistance to oxyimino-cephalosporins conferred by an alternative mechanism of hydrolysis by the Acinetobacter-derived cephalosporinase-33 (ADC-33), a class C beta-lactamase present in carbapenem-resistant Acinetobacter baumannii (CRAb).
The study identifies ADC-33, a class C beta-lactamase from Acinetobacter baumannii, as a key mediator of resistance to oxyimino-cephalosporins such as ceftazidime, ceftolozane, and cefiderocol. The resistance mechanism involves an alternative hydrolysis pathway, with structural and kinetic analyses revealing unique features of ADC-33 that enhance its catalytic efficiency towards these antibiotics.
Resistance to oxyimino-cephalosporins conferred by an alternative mechanism of hydrolysis by the Acinetobacter-derived cephalosporinase-33 (ADC-33), a class C β-lactamase present in carbapenem-resistant Acinetobacter baumannii (CRAb).
The study identifies ADC-33, a class C β-lactamase from Acinetobacter baumannii, as a key mediator of resistance to oxyimino-cephalosporins such as ceftazidime, ceftolozane, and cefiderocol. The resistance mechanism involves an alternative hydrolysis pathway, with structural and kinetic analyses revealing unique features of ADC-33 that enhance its catalytic efficiency towards these antibiotics.
Secondary bacterial infections of Carbapenem-Resistant Acinetobacter baumannii in patients with COVID-19 admitted to Chinese ICUs.
The study identifies blaOXA-23, blaOXA-66, and blaADC-73 as carbapenem resistance genes in Carbapenem-Resistant Acinetobacter baumannii (CRAB) isolates from patients with COVID-19 in Chinese ICUs.
Broadly reactive monoclonal antibodies against beta-lactamases for immunodetection of bacterial resistance to antibiotics.
The study describes broadly reactive monoclonal antibodies (MAbs) against AmpC beta-lactamases, which are key enzymes in bacterial resistance to beta-lactam antibiotics. These MAbs recognize a conserved epitope of 11 amino acids and show cross-reactivity with various AmpC beta-lactamases, including DHA-1, CMY-34, ACT-14, PDC-195, and ADC-144.
Local Genomic Epidemiology of Acinetobacter baumannii Circulating in Hospital and Non-hospital Environments in Kano, Northwest Nigeria.
The study identifies various AMR genes in Acinetobacter baumannii isolates from hospital and non-hospital environments in Kano, Nigeria, including bla OXA-66, bla OXA-180, bla ADC-25, aadA1, aph(3')-Ia, aph(3'' )-Ib, aac(3)-Ia, aph(6)-Id, tetB, sul1, and sul2, which confer resistance to beta-lactams, aminoglycosides, tetracyclines, and sulfonamides.
Nationwide surveillance of carbapenem-resistant Gram-negative pathogens in the Lebanese environment.
The study identified carbapenem-resistant Gram-negative bacteria in various environmental samples in Lebanon, including Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii. Key resistance genes detected include bla NDM-5, bla OXA-23, bla OXA-66, mexAB-OprM, bla IMP-1, and others, highlighting the widespread presence of carbapenem resistance in the environment.
Genomic Characterization and Antibiotic Resistance Profiles of Acinetobacter baumannii Isolates From Intensive Care Units in Vietnam.
The study identifies multiple AMR genes in three CRAB isolates, including blaOXA-23, blaOXA-66, blaADC-198, blaADC-73, and various aminoglycoside modifying enzymes, efflux pumps, and sulfonamide resistance genes, highlighting the extensive multidrug resistance in these isolates.
Genomic Characterization and Antibiotic Resistance Profiles of Acinetobacter baumannii Isolates From Intensive Care Units in Vietnam.
The study identifies multiple AMR genes in three CRAB isolates, including blaOXA-23, blaOXA-66, blaADC-198, blaADC-73, and various aminoglycoside modifying enzymes, efflux pumps, and sulfonamide resistance genes, highlighting the extensive multidrug resistance in these isolates.
Genomic insights into bacteriophages: a new frontier in AMR detection and phage therapy.
The paper discusses the identification of various AMR genes in Acinetobacter baumannii and other pathogens, highlighting their role in resistance to multiple antibiotics and the potential of phage therapy as an alternative treatment.
Genomic and phenotypic characterization of six multidrug-resistant Acinetobacter pittii isolates.
The study identified multiple beta-lactamase genes, including blaOXA-72, blaOXA-272, and blaOXA-255, which confer resistance to carbapenems. Additionally, other resistance genes such as blaADC-245, blaADC-150, and others were found to confer resistance to cephalosporins. Efflux pump genes like adeF, abaQ, and abeS were associated with resistance to fluoroquinolones and tetracyclines. The gene lpsB was linked to colistin resistance.
Genomic and phenotypic characterization of six multidrug-resistant Acinetobacter pittii isolates.
The study identified multiple beta-lactamase genes, including blaOXA-72, blaOXA-272, and blaOXA-255, which confer resistance to carbapenems. Additionally, other resistance genes such as blaADC-245, blaADC-150, and others were found to confer resistance to cephalosporins. Efflux pump genes like adeF, abaQ, and abeS were associated with resistance to fluoroquinolones and tetracyclines. The gene lpsB was linked to colistin resistance.
Genomic and phenotypic characterization of six multidrug-resistant Acinetobacter pittii isolates.
The study identified multiple beta-lactamase genes, including blaOXA-72, blaOXA-272, and blaOXA-255, which confer resistance to carbapenems. Additionally, other resistance genes such as blaADC-245, blaADC-150, and others were found to confer resistance to cephalosporins. Efflux pump genes like adeF, abaQ, and abeS were associated with resistance to fluoroquinolones and tetracyclines. The gene lpsB was linked to colistin resistance.
Genomic and phenotypic characterization of six multidrug-resistant Acinetobacter pittii isolates.
The study identified multiple beta-lactamase genes, including blaOXA-72, blaOXA-272, and blaOXA-255, which confer resistance to carbapenems. Additionally, other resistance genes such as blaADC-245, blaADC-150, and others were found to confer resistance to cephalosporins. Efflux pump genes like adeF, abaQ, and abeS were associated with resistance to fluoroquinolones and tetracyclines. The gene lpsB was linked to colistin resistance.
Genomic and phenotypic characterization of six multidrug-resistant Acinetobacter pittii isolates.
The study identified multiple beta-lactamase genes, including blaOXA-72, blaOXA-272, and blaOXA-255, which confer resistance to carbapenems. Additionally, other resistance genes such as blaADC-245, blaADC-150, and others were found to confer resistance to cephalosporins. Efflux pump genes like adeF, abaQ, and abeS were associated with resistance to fluoroquinolones and tetracyclines. The gene lpsB was linked to colistin resistance.
Orthopedic infections associated with distinct Acinetobacter strains in rural area of Qingdao, China.
The study identified multiple AMR genes in Acinetobacter isolates, including blaOXA-23, blaOXA-66, blaOXA-213, blaADC-6, mcr-4.3, amvA, and rsmA, highlighting the diversity of resistance mechanisms in different species.
Genomic characterization of multidrug-resistant clinical Acinetobacter baumannii isolates from a hospital in Paraguay.
The study identified multiple AMR genes in multidrug-resistant Acinetobacter baumannii isolates from Paraguay, including blaOXA-23, blaOXA-66, blaOXA-65, blaADC-73, blaADC-5, blaTEM-1, and various aminoglycoside, macrolide, sulfonamide, chloramphenicol, tetracycline, and trimethoprim resistance genes.
Genomic characterization of multidrug-resistant clinical Acinetobacter baumannii isolates from a hospital in Paraguay.
The study identified multiple AMR genes in multidrug-resistant Acinetobacter baumannii isolates from Paraguay, including blaOXA-23, blaOXA-66, blaOXA-65, blaADC-73, blaADC-5, blaTEM-1, and various aminoglycoside, macrolide, sulfonamide, chloramphenicol, tetracycline, and trimethoprim resistance genes.
The Road Less Traveled: Exploring the Genomic Characteristics and Antimicrobial Resistance Potential of Acinetobacter baumannii From the Indigenous Orang Asli Community in Peninsular Malaysia.
The study identified several beta-lactamase and cephalosporinase genes, including bla OXA-51, bla OXA-68, bla OXA-98, and various bla ADC variants, as well as tetracycline resistance gene tet(39) and aminoglycoside resistance gene ant(3'')-IIa in Acinetobacter baumannii isolates from the Orang Asli community. These genes contribute to resistance against carbapenems, cephalosporins, tetracyclines, and aminoglycosides.
The Road Less Traveled: Exploring the Genomic Characteristics and Antimicrobial Resistance Potential of Acinetobacter baumannii From the Indigenous Orang Asli Community in Peninsular Malaysia.
The study identified several beta-lactamase and cephalosporinase genes, including bla OXA-51, bla OXA-68, bla OXA-98, and various bla ADC variants, as well as tetracycline resistance gene tet(39) and aminoglycoside resistance gene ant(3'')-IIa in Acinetobacter baumannii isolates from the Orang Asli community. These genes contribute to resistance against carbapenems, cephalosporins, tetracyclines, and aminoglycosides.
The Road Less Traveled: Exploring the Genomic Characteristics and Antimicrobial Resistance Potential of Acinetobacter baumannii From the Indigenous Orang Asli Community in Peninsular Malaysia.
The study identified several beta-lactamase and cephalosporinase genes, including bla OXA-51, bla OXA-68, bla OXA-98, and various bla ADC variants, as well as tetracycline resistance gene tet(39) and aminoglycoside resistance gene ant(3'')-IIa in Acinetobacter baumannii isolates from the Orang Asli community. These genes contribute to resistance against carbapenems, cephalosporins, tetracyclines, and aminoglycosides.
The Road Less Traveled: Exploring the Genomic Characteristics and Antimicrobial Resistance Potential of Acinetobacter baumannii From the Indigenous Orang Asli Community in Peninsular Malaysia.
The study identified several beta-lactamase and cephalosporinase genes, including bla OXA-51, bla OXA-68, bla OXA-98, and various bla ADC variants, as well as tetracycline resistance gene tet(39) and aminoglycoside resistance gene ant(3'')-IIa in Acinetobacter baumannii isolates from the Orang Asli community. These genes contribute to resistance against carbapenems, cephalosporins, tetracyclines, and aminoglycosides.
The Road Less Traveled: Exploring the Genomic Characteristics and Antimicrobial Resistance Potential of Acinetobacter baumannii From the Indigenous Orang Asli Community in Peninsular Malaysia.
The study identified several beta-lactamase and cephalosporinase genes, including bla OXA-51, bla OXA-68, bla OXA-98, and various bla ADC variants, as well as tetracycline resistance gene tet(39) and aminoglycoside resistance gene ant(3'')-IIa in Acinetobacter baumannii isolates from the Orang Asli community. These genes contribute to resistance against carbapenems, cephalosporins, tetracyclines, and aminoglycosides.
The Road Less Traveled: Exploring the Genomic Characteristics and Antimicrobial Resistance Potential of Acinetobacter baumannii From the Indigenous Orang Asli Community in Peninsular Malaysia.
The study identified several beta-lactamase and cephalosporinase genes, including bla OXA-51, bla OXA-68, bla OXA-98, and various bla ADC variants, as well as tetracycline resistance gene tet(39) and aminoglycoside resistance gene ant(3'')-IIa in Acinetobacter baumannii isolates from the Orang Asli community. These genes contribute to resistance against carbapenems, cephalosporins, tetracyclines, and aminoglycosides.
The Road Less Traveled: Exploring the Genomic Characteristics and Antimicrobial Resistance Potential of Acinetobacter baumannii From the Indigenous Orang Asli Community in Peninsular Malaysia.
The study identified several beta-lactamase and cephalosporinase genes, including bla OXA-51, bla OXA-68, bla OXA-98, and various bla ADC variants, as well as tetracycline resistance gene tet(39) and aminoglycoside resistance gene ant(3'')-IIa in Acinetobacter baumannii isolates from the Orang Asli community. These genes contribute to resistance against carbapenems, cephalosporins, tetracyclines, and aminoglycosides.
The Road Less Traveled: Exploring the Genomic Characteristics and Antimicrobial Resistance Potential of Acinetobacter baumannii From the Indigenous Orang Asli Community in Peninsular Malaysia.
The study identified several beta-lactamase and cephalosporinase genes, including bla OXA-51, bla OXA-68, bla OXA-98, and various bla ADC variants, as well as tetracycline resistance gene tet(39) and aminoglycoside resistance gene ant(3'')-IIa in Acinetobacter baumannii isolates from the Orang Asli community. These genes contribute to resistance against carbapenems, cephalosporins, tetracyclines, and aminoglycosides.
The Road Less Traveled: Exploring the Genomic Characteristics and Antimicrobial Resistance Potential of Acinetobacter baumannii From the Indigenous Orang Asli Community in Peninsular Malaysia.
The study identified several beta-lactamase and cephalosporinase genes, including bla OXA-51, bla OXA-68, bla OXA-98, and various bla ADC variants, as well as tetracycline resistance gene tet(39) and aminoglycoside resistance gene ant(3'')-IIa in Acinetobacter baumannii isolates from the Orang Asli community. These genes contribute to resistance against carbapenems, cephalosporins, tetracyclines, and aminoglycosides.
The Road Less Traveled: Exploring the Genomic Characteristics and Antimicrobial Resistance Potential of Acinetobacter baumannii From the Indigenous Orang Asli Community in Peninsular Malaysia.
The study identified several beta-lactamase and cephalosporinase genes, including bla OXA-51, bla OXA-68, bla OXA-98, and various bla ADC variants, as well as tetracycline resistance gene tet(39) and aminoglycoside resistance gene ant(3'')-IIa in Acinetobacter baumannii isolates from the Orang Asli community. These genes contribute to resistance against carbapenems, cephalosporins, tetracyclines, and aminoglycosides.
The Road Less Traveled: Exploring the Genomic Characteristics and Antimicrobial Resistance Potential of Acinetobacter baumannii From the Indigenous Orang Asli Community in Peninsular Malaysia.
The study identified several beta-lactamase and cephalosporinase genes, including bla OXA-51, bla OXA-68, bla OXA-98, and various bla ADC variants, as well as tetracycline resistance gene tet(39) and aminoglycoside resistance gene ant(3'')-IIa in Acinetobacter baumannii isolates from the Orang Asli community. These genes contribute to resistance against carbapenems, cephalosporins, tetracyclines, and aminoglycosides.
The Road Less Traveled: Exploring the Genomic Characteristics and Antimicrobial Resistance Potential of Acinetobacter baumannii From the Indigenous Orang Asli Community in Peninsular Malaysia.
The study identified several beta-lactamase and cephalosporinase genes, including bla OXA-51, bla OXA-68, bla OXA-98, and various bla ADC variants, as well as tetracycline resistance gene tet(39) and aminoglycoside resistance gene ant(3'')-IIa in Acinetobacter baumannii isolates from the Orang Asli community. These genes contribute to resistance against carbapenems, cephalosporins, tetracyclines, and aminoglycosides.
Genomic Characterization of a Carbapenem-Resistant Acinetobacter pittii Strain Harboring Chromosome-Borne bla(NDM-1) from China.
The study characterizes a carbapenem-resistant Acinetobacter pittii strain AP8900 harboring the chromosome-borne bla(NDM-1) gene, which is located on the Tn125 composite transposon. The strain also carries other beta-lactam resistance genes, including blaADC-25 and blaOXA-526.
ISAba1-mediated bla(ADC) disruption restores third-generation cephalosporin susceptibility in a clinical Acinetobacter baumannii isolate.
The study shows that the insertion of IS Aba1 in the bla ADC-195 gene of a carbapenem-resistant A. baumannii isolate disrupts the gene, reducing ceftazidime resistance. Cloning an intact bla ADC-195 variant restored ceftazidime resistance, highlighting the role of IS Aba1 in modulating beta-lactamase activity.
ISAba1-mediated bla(ADC) disruption restores third-generation cephalosporin susceptibility in a clinical Acinetobacter baumannii isolate.
The study shows that the insertion of IS Aba1 in the bla ADC-195 gene of a carbapenem-resistant A. baumannii isolate disrupts the gene, reducing ceftazidime resistance. Cloning an intact bla ADC-195 variant restored ceftazidime resistance, highlighting the role of IS Aba1 in modulating beta-lactamase activity.
Gut microbiome profiling of a migratory Anser serrirostris population reveals two groups with distinct pathogen and ARG contents.
The study identified two distinct gut microbiome groups (E1 and E2) in a migratory Anser serrirostris population, with E1 showing higher abundances of opportunistic pathogens and antibiotic resistance genes (ARGs). Key ARGs included beta-lactamase-encoding genes such as blaCTX-M, blaZ, blaCARB-1, blaADC, blaPDC, and blaOXA-213, which were more prevalent in E1.
No comments yet. Be the first to comment!