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Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
subclass B1 metallo-beta-lactamase BlaB-10
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| BlaB-10 | Card DatabaseReference Gene CatalogResFinder Database | 3 | CARBAPENEM, AMOXICILLIN +2 | Elizabethkingia miricola +1 | - | 2010 | MAHD01000015.1 | WP_063857822.1 |
| BlaB-14 | Card DatabaseReference Gene CatalogResFinder Database | 3 | CARBAPENEM, AMOXICILLIN +2 | Elizabethkingia meningoseptica | - | 2012 | JN635697.1 | WP_034848068.1 |
| BlaB-15 | Card DatabaseReference Gene Catalog | 3 | CARBAPENEM | Elizabethkingia miricola | - | - | KR054962.1 | AKJ86507.1 |
| BlaB-17 | Card DatabaseReference Gene Catalog | 3 | CARBAPENEM | Elizabethkingia anophelis | - | - | CCAB010000101.1 | CDN73485.1 |
| BlaB-18 | Card DatabaseReference Gene CatalogReslit | 4 | CARBAPENEM, penicillin +2 | Elizabethkingia anophelis R26 +1 | Russia | 2022 | CP023401.1 | ATC35781.1 |
| BlaB-19 | Card DatabaseReference Gene Catalog | 3 | CARBAPENEM | Elizabethkingia meningoseptica | - | - | CP016376.1 | AQX05318.1 |
| BlaB-20 | Card DatabaseReference Gene Catalog | 3 | CARBAPENEM | Elizabethkingia anophelis | - | - | PJMA01000002.1 | PKR31511.1 |
| BlaB-22 | Card DatabaseReference Gene Catalog | 3 | CARBAPENEM | Elizabethkingia bruuniana | - | - | MAHV01000018.1 | OPB64500.1 |
| BlaB-23 | Card DatabaseReference Gene Catalog | 3 | CARBAPENEM | Elizabethkingia meningoseptica | - | - | MCJH01000002.1 | ODM55343.1 |
| BlaB-24 | Card DatabaseReference Gene Catalog | 3 | CARBAPENEM | Elizabethkingia bruuniana | - | - | MAHW01000003.1 | OPC66432.1 |
| BlaB-25 | Card DatabaseReference Gene Catalog | 3 | CARBAPENEM | Elizabethkingia miricola | - | - | CP023746.1 | ATL43418.1 |
| BlaB-26 | Card DatabaseReference Gene Catalog | 3 | CARBAPENEM | Elizabethkingia miricola | - | - | LSGQ01000033.1 | OBS11210.1 |
| BlaB-27 | Card DatabaseReference Gene Catalog | 2 | CARBAPENEM | Elizabethkingia occulta | - | - | MAHX01000018.1 | WP_078772815.1 |
| BlaB-28 | Card DatabaseReference Gene Catalog | 2 | CARBAPENEM | Elizabethkingia sp. YR214 +1 | - | - | QBUH01000004.1 | WP_107808007.1 |
| BlaB-29 | Card DatabaseReference Gene Catalog | 2 | CARBAPENEM | Elizabethkingia anophelis | - | - | LPXG01000019.1 | WP_081318900.1 |
| BlaB-30 | Card DatabaseReference Gene Catalog | 2 | CARBAPENEM | Elizabethkingia anophelis | - | - | FTRB01000015.1 | WP_087094142.1 |
| BlaB-32 | Card DatabaseReference Gene Catalog | 3 | CARBAPENEM | Elizabethkingia anophelis | - | - | MAHO01000018.1 | OPC44483.1 |
| BlaB-34 | Card DatabaseReference Gene Catalog | 2 | CARBAPENEM | Elizabethkingia bruuniana | - | - | MAHQ01000013.1 | WP_078678782.1 |
| BlaB-35 | Card DatabaseReference Gene Catalog | 3 | CARBAPENEM | Elizabethkingia meningoseptica | - | - | MAGZ01000015.1 | OPB96693.1 |
| BlaB-36 | Card DatabaseReference Gene Catalog | 2 | CARBAPENEM | Elizabethkingia miricola | - | - | CP011059.1 | WP_080889626.1 |
| BlaB-37 | Reference Gene Catalog | 1 | CARBAPENEM | Elizabethkingia miricola | - | - | MAHK01000015.1 | OPC34432.1 |
| BlaB-38 | Card DatabaseReference Gene Catalog | 3 | CARBAPENEM | Elizabethkingia miricola | - | - | MAGX01000004.1 | OPB88073.1 |
| BlaB-39 | Card DatabaseReference Gene Catalog | 2 | CARBAPENEM | Elizabethkingia ursingii | - | - | MBDS01000014.1 | WP_078778510.1 |
| BlaB-6 | Card DatabaseReference Gene Catalog | 3 | CARBAPENEM | Elizabethkingia miricola | - | - | MAHY01000013.1 | OPC68803.1 |
| BlaB-7 | Card DatabaseReference Gene CatalogResFinder Database | 3 | CARBAPENEM, AMOXICILLIN +2 | Elizabethkingia ursingii +1 | - | 2000 | MAIC01000004.1 | WP_063857829.1 |
| BlaB-8 | Card DatabaseReference Gene CatalogResFinder Database | 3 | CARBAPENEM, AMOXICILLIN +2 | Elizabethkingia ursingii +1 | - | 2000 | MAHB01000007.1 | WP_059324801.1 |
| BlaB-9 | Card DatabaseReference Gene CatalogResFinder Database | 3 | CARBAPENEM, AMOXICILLIN +2 | Elizabethkingia miricola +1 | - | 2010 | LIQC01000014.1 | WP_059154943.1 |
| BlaB-1 | Card DatabaseReference Gene Catalog | 3 | CARBAPENEM | Elizabethkingia meningoseptica | - | 2000 | NG_048691.1 | WP_029729112.1 |
| BlaB-11 | Card DatabaseReference Gene CatalogResFinder Database | 4 | AMOXICILLIN, AMPICILLIN +2 | Elizabethkingia meningoseptica | - | 2010 | NG_048693.1 | WP_063857823.1 |
| BlaB-12 | Card DatabaseReference Gene CatalogResFinder Database | 4 | AMOXICILLIN, AMPICILLIN +2 | Elizabethkingia meningoseptica | - | 2010 | NG_048694.1 | WP_063857824.1 |
| BlaB-13 | Card DatabaseReference Gene CatalogResFinder Database | 4 | AMOXICILLIN, AMPICILLIN +2 | Elizabethkingia meningoseptica | - | 2010 | NG_048695.1 | WP_063857825.1 |
| BlaB-16 | Card DatabaseReference Gene Catalog | 3 | CARBAPENEM | Elizabethkingia miricola | - | 2020 | NG_067205.1 | WP_086980232.1 |
| BlaB-2 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 5 | AMOXICILLIN, AMPICILLIN +3 | Elizabethkingia meningoseptica +1 | - | 2000, 2022 | NG_048697.1 | WP_063857826.1 |
| BlaB-3 | Card DatabaseReference Gene Catalog | 3 | CARBAPENEM | Elizabethkingia meningoseptica | - | 2000 | NG_048698.1 | WP_063857827.1 |
| BlaB-31 | Card DatabaseReference Gene Catalog | 3 | CARBAPENEM | Elizabethkingia meningoseptica | - | 2012 | NG_067216.1 | WP_078675249.1 |
| BlaB-33 | Card DatabaseReference Gene Catalog | 3 | CARBAPENEM | Elizabethkingia anophelis FMS-007 | - | 2015 | NG_067218.1 | WP_065161001.1 |
| BlaB-5 | Card DatabaseReference Gene CatalogResFinder Database | 4 | AMOXICILLIN, AMPICILLIN +2 | Elizabethkingia meningoseptica | - | 2000 | NG_048699.1 | WP_063857828.1 |
| blaB | Reslit | 10 | carbapenems, penicillin +6 | Chryseobacterium (Flavobacterium) meningosepticum +13 | United Kingdom|USA|France, India, South Australia, China, Taiwan, Brazil | 2000, 2002, 2007, 2012, 2021, 2022, 2024, 2025 | AF126542|AF162284 | - |
| blaB-2 | ResFinder Database | 1 | AMOXICILLIN, AMPICILLIN +1 | Elizabethkingia meningoseptica | - | 2000 | AF189300 | - |
| blaB-3 | ResFinder Database | 1 | AMOXICILLIN, AMPICILLIN +1 | Elizabethkingia meningoseptica | - | 2000 | AF189301, AF189299 | - |
| blaB-5 | ResFinder Database | 1 | AMOXICILLIN, AMPICILLIN +1 | Elizabethkingia meningoseptica | - | 2000 | AF189303 | - |
| blaB-6 | ResFinder Database | 1 | AMOXICILLIN, AMPICILLIN +1 | Elizabethkingia meningoseptica | - | 2000 | AF189302 | - |
| blaB-7 | ResFinder Database | 1 | AMOXICILLIN, AMPICILLIN +1 | Elizabethkingia meningoseptica | - | 2000 | AF189304 | - |
| blaB-8 | ResFinder Database | 1 | AMOXICILLIN, AMPICILLIN +1 | Elizabethkingia meningoseptica | - | 2000 | AF189305 | - |
| BlaB-21 | Card DatabaseReference Gene Catalog | 2 | CARBAPENEM | Elizabethkingia anophelis NUHP1 | - | 2002 | CP007547.1 | AIL46641.1 |
| blaB-9 | ResFinder Database | 1 | AMOXICILLIN, AMPICILLIN +1 | Elizabethkingia meningoseptica | - | 2010 | AY348324 | - |
| blaB-10 | ResFinder Database | 1 | AMOXICILLIN, AMPICILLIN +1 | Elizabethkingia meningoseptica | - | 2010 | AY348325 | - |
| blaB-11 | ResFinder Database | 1 | AMOXICILLIN, AMPICILLIN +1 | Elizabethkingia meningoseptica | - | 2010 | AY348326 | - |
| blaB-12 | ResFinder Database | 1 | AMOXICILLIN, AMPICILLIN +1 | Elizabethkingia meningoseptica | - | 2010 | EF595958 | - |
| blaB-13 | ResFinder Database | 1 | AMOXICILLIN, AMPICILLIN +1 | Elizabethkingia meningoseptica | - | 2010 | EF595959 | - |
| blaB-14 | ResFinder Database | 1 | AMOXICILLIN, AMPICILLIN +1 | Elizabethkingia meningoseptica | - | 2012 | JN635697 | - |
| BlaB | Reslit | 2 | imipenem, carbapenems | Elizabethkingia anophelis +2 | Taiwan, Brazil|India|Sweden|USA|Argentina|Italy|Japan | 2019, 2021 | MK360026|MK360027|MK360028|MK360029|MK360030|MK360031|MK360032|MK360033|MK360034|MK360035|MK360036|MK360037|MK360038|MK360039 | - |
| blaB-12_1 | Reslit | 1 | carbapenems | Elizabethkingia meningoseptica | Spain | 2019 | NZ_CP016378.1 | - |
Carbapenemases of Chryseobacterium (Flavobacterium) meningosepticum: distribution of blaB and characterization of a novel metallo-beta-lactamase gene, blaB3, in the type strain, NCTC 10016.
The study characterizes the blaB, blaB2, and blaB3 genes, which encode metallo-beta-lactamases in Chryseobacterium (Flavobacterium) meningosepticum, contributing to carbapenem resistance.
Carbapenemases of Chryseobacterium (Flavobacterium) meningosepticum: distribution of blaB and characterization of a novel metallo-beta-lactamase gene, blaB3, in the type strain, NCTC 10016.
Carbapenemases of Chryseobacterium (Flavobacterium) meningosepticum: distribution of blaB and characterization of a novel metallo-beta-lactamase gene, blaB3, in the type strain, NCTC 10016.
Carbapenemases of Chryseobacterium (Flavobacterium) meningosepticum: distribution of blaB and characterization of a novel metallo-beta-lactamase gene, blaB3, in the type strain, NCTC 10016.
Carbapenemases of Chryseobacterium (Flavobacterium) meningosepticum: distribution of blaB and characterization of a novel metallo-beta-lactamase gene, blaB3, in the type strain, NCTC 10016.
Carbapenemases of Chryseobacterium (Flavobacterium) meningosepticum: distribution of blaB and characterization of a novel metallo-beta-lactamase gene, blaB3, in the type strain, NCTC 10016.
Carbapenemases of Chryseobacterium (Flavobacterium) meningosepticum: distribution of blaB and characterization of a novel metallo-beta-lactamase gene, blaB3, in the type strain, NCTC 10016.
Carbapenemases of Chryseobacterium (Flavobacterium) meningosepticum: distribution of blaB and characterization of a novel metallo-beta-lactamase gene, blaB3, in the type strain, NCTC 10016.
Molecular and biochemical heterogeneity of class B carbapenem-hydrolyzing beta-lactamases in Chryseobacterium meningosepticum.
Molecular and biochemical heterogeneity of class B carbapenem-hydrolyzing beta-lactamases in Chryseobacterium meningosepticum.
Molecular and biochemical heterogeneity of class B carbapenem-hydrolyzing beta-lactamases in Chryseobacterium meningosepticum.
Molecular and biochemical heterogeneity of class B carbapenem-hydrolyzing beta-lactamases in Chryseobacterium meningosepticum.
Molecular and biochemical heterogeneity of class B carbapenem-hydrolyzing beta-lactamases in Chryseobacterium meningosepticum.
Molecular and biochemical heterogeneity of class B carbapenem-hydrolyzing beta-lactamases in Chryseobacterium meningosepticum.
Molecular and biochemical heterogeneity of class B carbapenem-hydrolyzing beta-lactamases in Chryseobacterium meningosepticum.
Molecular and biochemical heterogeneity of class B carbapenem-hydrolyzing beta-lactamases in Chryseobacterium meningosepticum.
Molecular and biochemical heterogeneity of class B carbapenem-hydrolyzing beta-lactamases in Chryseobacterium meningosepticum.
Molecular and biochemical heterogeneity of class B carbapenem-hydrolyzing beta-lactamases in Chryseobacterium meningosepticum.
Molecular and biochemical heterogeneity of class B carbapenem-hydrolyzing beta-lactamases in Chryseobacterium meningosepticum.
Molecular and biochemical heterogeneity of class B carbapenem-hydrolyzing beta-lactamases in Chryseobacterium meningosepticum.
Molecular and biochemical heterogeneity of class B carbapenem-hydrolyzing beta-lactamases in Chryseobacterium meningosepticum.
Overproduction and biochemical characterization of the Chryseobacterium meningosepticum BlaB metallo-beta-lactamase.
The study characterizes the BlaB metallo-beta-lactamase from Chryseobacterium meningosepticum, demonstrating its ability to hydrolyze various β-lactam antibiotics including penicillins, carbapenems, and cephalosporins.
Overproduction and biochemical characterization of the Chryseobacterium meningosepticum BlaB metallo-beta-lactamase.
Overproduction and biochemical characterization of the Chryseobacterium meningosepticum BlaB metallo-beta-lactamase.
Characteristics of beta-lactamases and their genes (blaA and blaB) in Yersinia intermedia and Y. frederiksenii.
The study identified and characterized the beta-lactamases Bla-A and Bla-B in Yersinia intermedia and Y. frederiksenii, showing their presence in all clinical and non-clinical strains and demonstrating their role in resistance to penicillins and cephalosporins.
Genetic diversity of chromosomal metallo-beta-lactamase genes in clinical isolates of Elizabethkingia meningoseptica from Korea.
Genetic diversity of chromosomal metallo-beta-lactamase genes in clinical isolates of Elizabethkingia meningoseptica from Korea.
Genetic diversity of chromosomal metallo-beta-lactamase genes in clinical isolates of Elizabethkingia meningoseptica from Korea.
Genetic diversity of chromosomal metallo-beta-lactamase genes in clinical isolates of Elizabethkingia meningoseptica from Korea.
Genetic diversity of chromosomal metallo-beta-lactamase genes in clinical isolates of Elizabethkingia meningoseptica from Korea.
Genetic diversity of chromosomal metallo-beta-lactamase genes in clinical isolates of Elizabethkingia meningoseptica from Korea.
Genetic diversity of chromosomal metallo-beta-lactamase genes in clinical isolates of Elizabethkingia meningoseptica from Korea.
Genetic diversity of chromosomal metallo-beta-lactamase genes in clinical isolates of Elizabethkingia meningoseptica from Korea.
Genetic diversity of chromosomal metallo-beta-lactamase genes in clinical isolates of Elizabethkingia meningoseptica from Korea.
Genetic diversity of chromosomal metallo-beta-lactamase genes in clinical isolates of Elizabethkingia meningoseptica from Korea.
Genetic diversity of chromosomal metallo-beta-lactamase genes in clinical isolates of Elizabethkingia meningoseptica from Korea.
Genetic diversity of chromosomal metallo-beta-lactamase genes in clinical isolates of Elizabethkingia meningoseptica from Korea.
Genetic diversity of chromosomal metallo-beta-lactamase genes in clinical isolates of Elizabethkingia meningoseptica from Korea.
Genetic diversity of chromosomal metallo-beta-lactamase genes in clinical isolates of Elizabethkingia meningoseptica from Korea.
Genetic diversity of chromosomal metallo-beta-lactamase genes in clinical isolates of Elizabethkingia meningoseptica from Korea.
Genetic diversity of chromosomal metallo-beta-lactamase genes in clinical isolates of Elizabethkingia meningoseptica from Korea.
Genetic diversity of chromosomal metallo-beta-lactamase genes in clinical isolates of Elizabethkingia meningoseptica from Korea.
Genetic diversity of chromosomal metallo-beta-lactamase genes in clinical isolates of Elizabethkingia meningoseptica from Korea.
Carbapenem resistance in Elizabethkingia meningoseptica is mediated by metallo-beta-lactamase BlaB.
The study identifies BlaB as the primary metallo-beta-lactamase responsible for carbapenem resistance in Elizabethkingia meningoseptica, demonstrating its functional role in hydrolyzing imipenem and meropenem.
Carbapenem resistance in Elizabethkingia meningoseptica is mediated by metallo-β-lactamase BlaB.
Carbapenem resistance in Elizabethkingia meningoseptica is mediated by metallo-β-lactamase BlaB.
Carbapenem resistance in Elizabethkingia meningoseptica is mediated by metallo-β-lactamase BlaB.
Genetic diversity analyses of antimicrobial resistance genes in clinical Chryseobacterium meningosepticum isolated from Hefei, China.
Genetic diversity analyses of antimicrobial resistance genes in clinical Chryseobacterium meningosepticum isolated from Hefei, China.
Complete Genome Sequence of Elizabethkingia meningoseptica, Isolated from a T-Cell Non-Hodgkin's Lymphoma Patient.
Complete Genome Sequence of Elizabethkingia meningoseptica, Isolated from a T-Cell Non-Hodgkin's Lymphoma Patient.
In vitro activities of imipenem, vancomycin, and rifampicin against clinical Elizabethkingia species producing BlaB and GOB metallo-beta-lactamases.
The study identifies BlaB and GOB metallo-beta-lactamases as the primary cause of imipenem resistance in clinical Elizabethkingia species, with BlaB and GOB showing species-specific variations and differing hydrolysis efficiencies.
Carbapenemase-Producing Elizabethkingia Meningoseptica from Healthy Pigs Associated with Colistin Use in Spain.
The study identifies two carbapenemase genes, blaB-12_1 and blaGOB-17_1, in a carbapenemase-producing isolate of Elizabethkingia meningoseptica from healthy pigs in Spain, suggesting that colistin use may favor the selection and persistence of carbapenem-resistant bacteria.
Whole-genome analysis of the potentially zoonotic Elizabethkingia miricola FL160902 with two new chromosomal MBL gene variants.
Whole-genome analysis of the potentially zoonotic Elizabethkingia miricola FL160902 with two new chromosomal MBL gene variants.
Metallo-beta-lactamases in the Age of Multidrug Resistance: From Structure and Mechanism to Evolution, Dissemination, and Inhibitor Design.
This review discusses the role of metallo-beta-lactamases (MBLs) in multidrug resistance, focusing on their structure, mechanism, and contribution to resistance against β-lactam antibiotics. It highlights the importance of MBLs in the spread of resistance and the challenges they pose for inhibitor design.
Genomic analysis of Elizabethkingia species from aquatic environments: Evidence for potential clinical transmission.
The study identified novel blaGOB and blaB carbapenemases and extended-spectrum beta-lactamase blaCME alleles in Elizabethkingia spp., highlighting their role in carbapenem and cephalosporin resistance.
Isolation of Elizabethkingia anophelis From COVID-19 Swab Kits.
The study identified multiple beta-lactamase genes (bla B, bla CME, bla GOB, and bla OXA), as well as the anti-macrolide gene ere(D), the sulfa-resistant gene sul2, and the anti-tetracycline gene tet(X) in Elizabethkingia anophelis isolates, indicating multidrug resistance.
Antimicrobial Resistance and Comparative Genomic Analysis of Elizabethkingia anophelis subsp. endophytica Isolated from Raw Milk.
The study reports the first isolation of Elizabethkingia anophelis subsp. endophytica from raw milk in Russia, highlighting its multidrug resistance and the presence of various AMR genes including beta-lactamases and efflux pumps.
New Beta-lactamases in Candidate Phyla Radiation: Owning Pleiotropic Enzymes Is a Smart Paradigm for Microorganisms with a Reduced Genome.
The study identified five putative beta-lactamase-encoding genes from the CPR resistome, which exhibited hydrolytic activity against certain beta-lactam antibiotics and RNA. These enzymes were expressed in E. coli and characterized using biochemical assays.
The individual contributions of blaB, blaGOB and blaCME on MICs of β-lactams in Elizabethkingia anophelis.
The study identified that blaB, blaGOB, and blaCME contribute to β-lactam resistance in Elizabethkingia anophelis, with blaB being the primary contributor to carbapenem resistance and blaCME contributing to resistance against ceftazidime and cefepime.
Potential involvement of beta-lactamase homologous proteins in resistance to beta-lactam antibiotics in gram-negative bacteria of the ESKAPEE group.
The study identifies and characterizes beta-lactamase homologous proteins in gram-negative bacteria of the ESKAPEE group, highlighting their potential role in resistance to beta-lactam antibiotics.
A novel pathogenic species of genus Stenotrophomonas: Stenotrophomonas pigmentata sp. nov.
The study identifies a novel pathogenic species, Stenotrophomonas pigmentata sp. nov., which exhibits resistance to multiple antibiotics, including β-lactams, carbapenems, and trimethoprim-sulfamethoxazole. Several multidrug resistance efflux pump and antibiotic resistance genes were found in its genome.
Genomic and phenotypic characterization of Chryseomicrobium imtechense from canine pyometra.
The study identified the presence of resistance genes to tetracyclines, fluoroquinolones, beta-lactams, and multidrug resistance in the genome of Chryseomicrobium imtechense LBV029/19. Specifically, the blaB gene was found to confer resistance to cephalosporins.
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