Browse AMR Genes

Explore antimicrobial resistance genes from the literature

blaCMY-2

beta-lactamase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to blaCMY-2

Browse AMR rules for blaCMY-2

Overview

Drug Classes: cefotaxime|aztreonam
Organisms: E. coli
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
G214E	-	-	E. coli	cefotaxime\|aztreonam	Reslit	Candidate

Papers1

1

Enhancing resistance to cephalosporins in class C beta-lactamases: impact of Gly214Glu in CMY-2.

PMID 19938877 · 2010

The Gly214Glu substitution in CMY-32 enhances resistance to cefotaxime and aztreonam compared to CMY-2.

Mutation Information

blaCMY-2: p.G214E

Protein Change: G214E
Organisms: E. coli
Confers Resistance To: cefotaxime|aztreonam
Validation Method: comparison with CMY-2 and MIC testing
Source Database: Reslit