Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
carbapenem-hydrolyzing class A beta-lactamase CRH-2
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| blaCRH-2 | Card DatabaseReference Gene Catalog | 3 | CARBAPENEM | Chromobacterium haemolyticum | - | - | KY773614.1 | AQZ55549.1 |
| blaCRH-3 | Card DatabaseReference Gene Catalog | 3 | CARBAPENEM | Chromobacterium haemolyticum | - | - | KY773615.1 | AQZ55550.1 |
| blaCRH-4 | Reference Gene Catalog | 1 | CARBAPENEM | Chromobacterium haemolyticum | - | - | LC873139.1 | BGC54460.1 |
| blaCRH-1 | Card DatabaseReference Gene CatalogReslit | 3 | CARBAPENEM, penicillin +2 | Chromobacterium haemolyticum +1 | - | 2016, 2023 | NG_054656.1 | WP_043592266.1 |
Chromobacterium spp. harbour Ambler class A β-lactamases showing high identity with KPC.
Biochemical and Structural Characterization of CRH-1, a Carbapenemase from Chromobacterium haemolyticum Related to KPC β-Lactamases.
CRH-1, a carbapenemase from Chromobacterium haemolyticum, confers resistance to penicillins, cephalosporins, and carbapenems. It shows similar hydrolytic efficiency to KPC-2 but is poorly inhibited by clavulanic acid.
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