Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
putative cephalosporinase
Overview
Genetic analysis of the beta-lactamases of Mycobacterium tuberculosis and Mycobacterium smegmatis and susceptibility to beta-lactam antibiotics.
The study identifies and characterizes beta-lactamases blaC, blaS, and a putative cephalosporinase blaE in Mycobacterium tuberculosis and Mycobacterium smegmatis, demonstrating their roles in beta-lactam resistance through increased susceptibility in mutants lacking these genes.
Genetic analysis of the beta-lactamases of Mycobacterium tuberculosis and Mycobacterium smegmatis and susceptibility to beta-lactam antibiotics.
Recent Advances in Methods to Detect Drug-Resistant Mtb
The paper discusses intrinsic and acquired drug resistance mechanisms in Mycobacterium tuberculosis, highlighting beta-lactamases (blaA, blaC, blaE), erm gene-mediated macrolide/lincosamide/streptogramin B resistance, mfpA-mediated fluoroquinolone/viomycin/capreomycin resistance, and the role of the Eis protein in aminoglycoside resistance. It also identifies mutations in rpoB and gyrA associated with rifampicin and fluoroquinolone resistance.
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