Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
beta-lactamase
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| blaLAT-1 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 6 | ceftazidime, cefotaxime +13 | Escherichia coli +2 | Europe | 1994, 2005, 2024 | X78117.1 | CAA55007.1 |
| blaLAT | Reslit | 2 | beta lactams, ceftazidime +1 | Klebsiella pneumoniae ATCC BAA-2146 +1 | Greece, Mexico | 2016, 2025 | - | - |
| blaLAT-3 | Reference Gene CatalogResFinder DatabaseReslit | 3 | cefotaxime, TICARCILLIN +11 | Salmonella enterica serovar Heidelberg +2 | Japan | 1997, 2021 | U77414.1 | AAB80855.1 |
Practical methods using boronic acid compounds for identification of class C beta-lactamase-producing Klebsiella pneumoniae and Escherichia coli.
The study identifies and characterizes several plasmid-mediated class C beta-lactamases, including CMY-2, CMY-8, CMY-9, FOX-5, MOX-1, ACT-1, and LAT-1, which confer resistance to ceftazidime and cefotaxime in Escherichia coli and Klebsiella pneumoniae. The researchers developed practical methods using boronic acid compounds, such as 3-aminophenylboronic acid (APB), to detect these beta-lactamases.
Streaming algorithms for identification of pathogens and antibiotic resistance potential from real-time MinION(TM) sequencing.
The study presents a real-time analysis framework for MinION sequencing data, demonstrating the ability to identify pathogens and antibiotic resistance genes within a few hours of sequencing. Key resistance genes identified include blaSHV, mphA, strA, strB, blaTEM, sul2, blaOXA, aac3, aac6, blaCMY, blaCFE, blaLAT, blaBIL, QnrB, aadA, oqxA, tetA, oqxB, rmtC, sul1, sul3, fosA, blaNDM, oqxA, blaSHV, oqxB, aadB, sul1, sul3, blaOXA, blaOKP, fosA, blaSHV, blaOKP, blaLEN, oqxA, and oqxB.
Antimicrobial Resistance in Salmonella Isolated from Food Workers and Chicken Products in Japan.
The study identified several beta-lactamase genes, including bla CMY-2, bla CTX-M-15, bla CTX-M-55, bla TEM-52B, bla LAT-3, bla LAP-2, and bla TEM-1, which were associated with cefotaxime resistance in Salmonella isolates from food workers and chicken products in Japan.
Relative inhibitory activities of newly developed diazabicyclooctanes, boronic acid derivatives, and penicillin-based sulfone beta-lactamase inhibitors against broad-spectrum AmpC beta-lactamases.
The study evaluates the inhibitory activities of various beta-lactamase inhibitors against a wide range of AmpC beta-lactamases, identifying the effectiveness of certain inhibitors like durlobactam and zidebactam in reducing the MIC values of β-lactam antibiotics against AmpC-producing strains.
Escherichia coli causing bloodstream infections in Mexican paediatric patients: molecular typing, antimicrobial resistance, virulence factors, and clinical features.
The study identified CTX-M-type ESBLs as the main mediators of resistance to 3GCs and 4GCs in E. coli isolates causing bloodstream infections in Mexican paediatric patients. The aac(6')-Ib-cr gene was also detected, contributing to aminoglycoside resistance.
Nucleotide sequence of a plasmid-mediated cephalosporinase gene (blaLAT-1) found in Klebsiella pneumoniae.
Nucleotide sequence of a plasmid-mediated cephalosporinase gene (blaLAT-1) found in Klebsiella pneumoniae.
Nucleotide sequence of a plasmid-mediated cephalosporinase gene (blaLAT-1) found in Klebsiella pneumoniae.
Nucleotide sequence of a plasmid-mediated cephalosporinase gene (blaLAT-1) found in Klebsiella pneumoniae.
A plasmid-mediated CMY-2 beta-lactamase from an Algerian clinical isolate of Salmonella senftenberg.
A plasmid-mediated CMY-2 beta-lactamase from an Algerian clinical isolate of Salmonella senftenberg.
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