Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
CMY-1/MOX family class C beta-lactamase MOX-10
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| blaMOX-10 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Aeromonas caviae | - | - | LN609374.1 | CEF57507.1 |
| blaMOX-11 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Aeromonas media | - | - | LN609375.1 | CEF57508.1 |
| blaMOX-12 | Card DatabaseReference Gene CatalogReslit | 5 | CEPHALOSPORIN, beta lactams +2 | Aeromonas caviae +1 | Warsaw, Poland, China | 2017, 2025 | JTBG02000004.1 | PNO62147.1 |
| blaMOX-14 | Card DatabaseReference Gene Catalog | 3 | CEPHALOSPORIN | Proteus mirabilis | - | - | MN550985.1 | QFR38192.1 |
| blaMOX-15 | Card DatabaseReference Gene CatalogReslit | 3 | CEPHALOSPORIN, cefotaxime +2 | Aeromonas caviae | Norway | 2023 | MZ133817.1 | QUW44775.1 |
| blaMOX-16 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Aeromonas caviae | - | - | LC659430.1 | BDC77865.1 |
| blaMOX-17 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Aeromonas caviae | - | - | OP142444.1 | UUT29086.1 |
| blaMOX-18 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Aeromonas caviae | - | - | LC732553.1 | BDS51123.1 |
| blaMOX-19 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Aeromonas caviae | - | - | LC732554.1 | BDS51124.1 |
| blaMOX-20 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Aeromonas caviae | - | - | LC732555.1 | BDS51125.1 |
| blaMOX-21 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Aeromonas caviae | - | - | LC732556.1 | BDS51126.1 |
| blaMOX-22 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Aeromonas caviae | - | - | LC733692.1 | BDT38927.1 |
| blaMOX-23 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Aeromonas caviae | - | - | LC733693.1 | BDT38928.1 |
| blaMOX-24 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Aeromonas caviae | - | - | LC733694.1 | BDT38929.1 |
| blaMOX-25 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Aeromonas caviae | - | - | LC733695.1 | BDT38930.1 |
| blaMOX-26 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Aeromonas veronii | - | - | OR209682.1 | WJR95507.1 |
| blaMOX-27 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Aeromonas caviae | - | - | OR209684.1 | WJR95509.1 |
| blaMOX-28 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Aeromonas hydrophila | - | - | OR209687.1 | WJR95512.1 |
| blaMOX-29 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Aeromonas hydrophila | - | - | OR209688.1 | WJR95513.1 |
| blaMOX-3 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 5 | UNKNOWN BETA-LACTAM, CEPHALOSPORIN +1 | Aeromonas sp. HCUZ 2422275 +1 | Europe|Portugal | 2022 | EU515248.1 | ACA30419.1 |
| blaMOX-30 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Aeromonas hydrophila | - | - | OR209689.1 | WJR95514.1 |
| blaMOX-31 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Aeromonas caviae | - | - | OR243294.1 | WKT26717.1 |
| blaMOX-32 | Reference Gene Catalog | 1 | CEPHALOSPORIN | Escherichia albertii | - | - | LC917618.1 | BHQ84536.1 |
| blaMOX-5 | Card DatabaseReference Gene CatalogResFinder Database | 4 | UNKNOWN BETA-LACTAM, CEPHALOSPORIN | Aeromonas caviae | - | - | GQ152600.1 | ACS44783.1 |
| blaMOX-7 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 5 | UNKNOWN BETA-LACTAM, CEPHALOSPORIN +2 | Aeromonas caviae | India | 2022 | GQ152602.1 | ACS44785.1 |
| blaMOX-8 | Card DatabaseReference Gene Catalog | 2 | CEPHALOSPORIN | Aeromonas caviae | - | - | JX173956.1 | AGH56079.1 |
| blaCMY-8b | Card DatabaseReference Gene CatalogResFinder Database | 5 | TICARCILLIN, CEPHALOSPORIN +10 | Klebsiella pneumoniae | - | 2010 | NG_048887.1 | WP_063859897.1 |
| blaMOX-13 | Card DatabaseReference Gene CatalogReslit | 4 | CEPHALOSPORIN, ceftriaxone +1 | Citrobacter sp. +1 | China | 2022, 2024 | NG_055585.1 | WP_096807444.1 |
| blaCMY-8 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 8 | cefotaxime, cefoxitin +18 | Klebsiella pneumoniae +1 | Taiwan, Guadeloupe, China | 2000, 2005, 2017, 2021 | AF167990 | AAD50818.2 |
| blaCMY-11 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 5 | TICARCILLIN, CEPHALOSPORIN +11 | Escherichia coli | Korea | 2002, 2004, 2009 | AF357599.1 | AAK31370.1 |
| blaMOX-2 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 8 | cefepime, cefoxitin +9 | Klebsiella pneumoniae +3 | Greece, Tunisia, Bangladesh|Brazil|Greece|Italy|Kenya|South Africa|Thailand|Uganda|Vietnam, Europe | 2002, 2016, 2024 | AJ276453 | CAB82578.1 |
| blaCMY-9 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 9 | ceftazidime, cefotaxime +17 | Escherichia coli +2 | Japan, Bangladesh, Mexico|Mexico City | 2002, 2005, 2006, 2023 | AB061794 | BAB72158.1 |
| blaCMY-10 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 9 | TICARCILLIN, CEPHALOSPORIN +16 | Klebsiella aerogenes +4 | Korea, Croatia|India, Global, Boston|California|New York | 2003, 2004, 2009, 2017, 2022, 2025 | AF357597.1 | AAK31368.1 |
| blaCMY-1 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 15 | cefotaxime, ceftazidime +21 | Klebsiella pneumoniae +8 | South Korea, Estonia, Japan, Europe|Spain, Italy, Belgium, Egypt, Karachi, Pakistan, Nile Delta region of Egypt, Bangladesh, Northern Italy | 1996, 2004, 2019, 2021, 2022, 2023, 2024 | OL872167|OL872168|OL872169|OL872170|OL872171|OL872179|OL840852 | CAA63264.1 |
| blaMOX-1 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 8 | ceftazidime, cefotaxime +5 | Escherichia coli +2 | China | 1994, 2005, 2007, 2014, 2021 | AB194682|AJ416341|AJ416342|D13304|X78117|Y16410|AJ133121|AJ278995|M37839|U58495|X77455|X98099|AF148851|AF301532|AF117747|AC007661|BC112171 | BAA02563.2 |
| blaCMY-19 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 6 | cefoxitin, cefotaxime +16 | Escherichia coli +2 | Japan | 2006, 2007 | AB194410 | BAE48233.1 |
| blaMOX | Reslit | 15 | cephalosporins, cefoxitin +10 | Escherichia coli +12 | Iran, Libya, Mozambique, southeastern China, Pakistan, Portugal, China, China|global, Zagreb, Croatia, India, USA|China|India|Thailand|Brazil|Hungary|South Africa|Egypt|Tunisia|Europe|Asia, Brazil, Europe | 2009, 2014, 2017, 2018, 2021, 2022, 2023, 2024, 2025 | ERS8292187|ERS82922188|ERS8292189 | - |
| blaMOX-4 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 7 | ampicillin, cefoxitin +6 | Aeromonas caviae +1 | China, Tanzania, Japan | 2010, 2018, 2025 | FJ262599.1 | ACI89425.1 |
| bla(MOX-1) | Reslit | 2 | cefoxitin, cefotaxime +4 | Klebsiella oxytoca +2 | Kinki region of Japan|Japan, Osaka, Japan | 2010, 2022 | LC670768|LC348383|AP025670|AP025671 | - |
| blaMOX-6 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 5 | UNKNOWN BETA-LACTAM, CEPHALOSPORIN +2 | Aeromonas caviae | China | 2011, 2020 | GQ152601.1 | ACS44784.1 |
| MOX | Reslit | 6 | cephalosporins, ceftriaxone +2 | Pseudomonas sp. +12 | Egypt, Southern India, Bangkok|Nonthaburi, Europe, Bahrain, Iran | 2014, 2015, 2020, 2021, 2022 | FJ997868.1|FJ262599.1 | - |
| blaMOX-9 | Card DatabaseReference Gene CatalogReslit | 5 | CEPHALOSPORIN, ampicillin +4 | Citrobacter freundii +2 | Croatia|India, Norway | 2015, 2017, 2022, 2023 | KJ746495.3 | AIG22447.1 |
| blaMOX-like | Reslit | 1 | amoxicillin, ampicillin | Escherichia coli | Egypt | 2018 | - | - |
| blaMOX -like | Reslit | 1 | penicillin, cephalosporins | Escherichia coli | Egypt | 2018 | - | - |
| bla_MOX | Reslit | 2 | cephalosporins | Escherichia coli +1 | Germany|Kosovo|Ukraine|Afghanistan, China | 2023 | PRJNA902936 | - |
| bla_MOX-7 | Reslit | 1 | cephalosporins, penicillin | Aeromonas caviae | India | 2022 | JAJVCV000000000|JAJVCT000000000|JAJVCU000000000|JAJVCW000000000|JACGXR000000000.1|CP046407.1|ANNT00000000.1|LZFM00000000.1|JZTH00000000.1|JZTG00000000.1|CP022550.1|WVRP00000000.1|CP032839.1|LXJN00000000.1|JZTF00000000.1|JAJVCW000000000.1 | - |
| mox | Reslit | 1 | ampicillin, cefoxitin +4 | Aeromonas caviae | Karachi, Pakistan | 2024 | PRJEB15489|PRJEB1611 | - |
Prevalence of SHV-12 among clinical isolates of Klebsiella pneumoniae producing extended-spectrum beta-lactamases and identification of a novel AmpC enzyme (CMY-8) in Southern Taiwan.
The study identifies SHV-12 as a prevalent extended-spectrum beta-lactamase in Klebsiella pneumoniae isolates and characterizes a novel AmpC beta-lactamase, CMY-8, which confers resistance to cephalosporins and cephamycins.
Prevalence of SHV-12 among clinical isolates of Klebsiella pneumoniae producing extended-spectrum beta-lactamases and identification of a novel AmpC enzyme (CMY-8) in Southern Taiwan.
Prevalence of SHV-12 among clinical isolates of Klebsiella pneumoniae producing extended-spectrum beta-lactamases and identification of a novel AmpC enzyme (CMY-8) in Southern Taiwan.
Prevalence of SHV-12 among clinical isolates of Klebsiella pneumoniae producing extended-spectrum beta-lactamases and identification of a novel AmpC enzyme (CMY-8) in Southern Taiwan.
Characterization of blaCMY-11, an AmpC-type plasmid-mediated beta-lactamase gene in a Korean clinical isolate of Escherichia coli.
Characterization of blaCMY-11, an AmpC-type plasmid-mediated beta-lactamase gene in a Korean clinical isolate of Escherichia coli.
Characterization of blaCMY-11, an AmpC-type plasmid-mediated beta-lactamase gene in a Korean clinical isolate of Escherichia coli.
Novel plasmid-encoded class C beta-lactamase (MOX-2) in Klebsiella pneumoniae from Greece.
The study identifies a novel plasmid-encoded class C beta-lactamase, MOX-2, in a multidrug-resistant Klebsiella pneumoniae isolate from Greece, which exhibits high hydrolytic activity against various beta-lactam antibiotics.
Novel plasmid-encoded class C beta-lactamase (MOX-2) in Klebsiella pneumoniae from Greece.
Novel plasmid-encoded class C beta-lactamase (MOX-2) in Klebsiella pneumoniae from Greece.
Novel plasmid-encoded class C beta-lactamase (MOX-2) in Klebsiella pneumoniae from Greece.
Characterization of a novel plasmid-mediated cephalosporinase (CMY-9) and its genetic environment in an Escherichia coli clinical isolate.
The study identifies a novel plasmid-mediated cephalosporinase, CMY-9, which confers resistance to several β-lactam antibiotics, including ceftazidime, cefpirome, cefotaxime, cefminox, cefoxitin, and moxalactam. The gene was cloned and characterized in E. coli.
Characterization of a novel plasmid-mediated cephalosporinase (CMY-9) and its genetic environment in an Escherichia coli clinical isolate.
Characterization of a novel plasmid-mediated cephalosporinase (CMY-9) and its genetic environment in an Escherichia coli clinical isolate.
Characterization of a novel plasmid-mediated cephalosporinase (CMY-9) and its genetic environment in an Escherichia coli clinical isolate.
Characterization of a novel plasmid-mediated cephalosporinase (CMY-9) and its genetic environment in an Escherichia coli clinical isolate.
Characterization of blaCMY-10 a novel, plasmid-encoded AmpC-type beta-lactamase gene in a clinical isolate of Enterobacter aerogenes.
Characterization of blaCMY-10 a novel, plasmid-encoded AmpC-type beta-lactamase gene in a clinical isolate of Enterobacter aerogenes.
Characterization of blaCMY-10 a novel, plasmid-encoded AmpC-type beta-lactamase gene in a clinical isolate of Enterobacter aerogenes.
Dissemination of Escherichia coli producing AmpC-type beta-lactamase (CMY-11) in Korea.
Dissemination of transferable AmpC-type beta-lactamase (CMY-10) in a Korean hospital.
Epidemiology and clinical features of bloodstream infections caused by AmpC-type-beta-lactamase-producing Klebsiella pneumoniae.
The study identifies DHA-1 and CMY-1 beta-lactamase genes as major contributors to AmpC-type beta-lactamase production in Klebsiella pneumoniae, leading to resistance against extended-spectrum cephalosporins and carbapenems.
Practical methods using boronic acid compounds for identification of class C beta-lactamase-producing Klebsiella pneumoniae and Escherichia coli.
The study identifies and characterizes several plasmid-mediated class C beta-lactamases, including CMY-2, CMY-8, CMY-9, FOX-5, MOX-1, ACT-1, and LAT-1, which confer resistance to ceftazidime and cefotaxime in Escherichia coli and Klebsiella pneumoniae. The researchers developed practical methods using boronic acid compounds, such as 3-aminophenylboronic acid (APB), to detect these beta-lactamases.
Practical methods using boronic acid compounds for identification of class C beta-lactamase-producing Klebsiella pneumoniae and Escherichia coli.
The study identifies and characterizes several plasmid-mediated class C beta-lactamases, including CMY-2, CMY-8, CMY-9, FOX-5, MOX-1, ACT-1, and LAT-1, which confer resistance to ceftazidime and cefotaxime in Escherichia coli and Klebsiella pneumoniae. The researchers developed practical methods using boronic acid compounds, such as 3-aminophenylboronic acid (APB), to detect these beta-lactamases.
Practical methods using boronic acid compounds for identification of class C beta-lactamase-producing Klebsiella pneumoniae and Escherichia coli.
The study identifies and characterizes several plasmid-mediated class C beta-lactamases, including CMY-2, CMY-8, CMY-9, FOX-5, MOX-1, ACT-1, and LAT-1, which confer resistance to ceftazidime and cefotaxime in Escherichia coli and Klebsiella pneumoniae. The researchers developed practical methods using boronic acid compounds, such as 3-aminophenylboronic acid (APB), to detect these beta-lactamases.
Horizontal Transfer of blaCMY-bearing plasmids among clinical Escherichia coli and Klebsiella pneumoniae isolates and emergence of cefepime-hydrolyzing CMY-19.
The study identifies blaCMY-9 and blaCMY-19 genes encoding beta-lactamases that confer resistance to various beta-lactam antibiotics, including cefepime. A single amino acid substitution (I292S) in CMY-19 expands its hydrolytic activity against certain cephalosporins compared to CMY-9.
Horizontal Transfer of blaCMY-bearing plasmids among clinical Escherichia coli and Klebsiella pneumoniae isolates and emergence of cefepime-hydrolyzing CMY-19.
The study identifies blaCMY-9 and blaCMY-19 genes encoding beta-lactamases that confer resistance to various beta-lactam antibiotics, including cefepime. A single amino acid substitution (I292S) in CMY-19 expands its hydrolytic activity against certain cephalosporins compared to CMY-9.
Horizontal transfer of blaCMY-bearing plasmids among clinical Escherichia coli and Klebsiella pneumoniae isolates and emergence of cefepime-hydrolyzing CMY-19.
Horizontal transfer of blaCMY-bearing plasmids among clinical Escherichia coli and Klebsiella pneumoniae isolates and emergence of cefepime-hydrolyzing CMY-19.
Horizontal transfer of blaCMY-bearing plasmids among clinical Escherichia coli and Klebsiella pneumoniae isolates and emergence of cefepime-hydrolyzing CMY-19.
Horizontal transfer of blaCMY-bearing plasmids among clinical Escherichia coli and Klebsiella pneumoniae isolates and emergence of cefepime-hydrolyzing CMY-19.
Multiplex Asymmetric PCR-Based Oligonucleotide Microarray for Detection of Drug Resistance Genes Containing Single Mutations in Enterobacteriaceae
The study developed a multiplex asymmetric PCR-based microarray for detecting drug resistance genes containing single mutations in Enterobacteriaceae, focusing on beta-lactamase genes such as bla SHV, bla TEM, bla CTX-M-3, bla CTX-M-9, bla DHA-1, bla CMY-2, bla MOX-1, bla ACC-1, bla FOX-5, and bla MIR-1. It also identified six point mutations in the bla SHV gene.
Exact location of the region responsible for the extended substrate spectrum in class C beta-lactamases.
The study identifies the R2 loop (residues 289 to 307) as the critical region responsible for the extended substrate spectrum in class C beta-lactamases, particularly highlighting the I292S substitution in CMY-19 that expands resistance to ceftazidime, cefepime, and cefpirome.
Identification of plasmid-mediated AmpC beta-lactamases in Escherichia coli, Klebsiella spp., and proteus species can potentially improve reporting of cephalosporin susceptibility testing results.
The study identifies plasmid-mediated AmpC beta-lactamases in Escherichia coli, Klebsiella spp., and Proteus species, highlighting their role in cephalosporin resistance and the importance of APBA testing for accurate susceptibility reporting.
CTX-M-14 and CTX-M-15 enzymes are the dominant type of extended-spectrum beta-lactamase in clinical isolates of Escherichia coli from Korea.
The study identifies CTX-M-14 and CTX-M-15 as the dominant extended-spectrum beta-lactamases in clinical isolates of Escherichia coli in Korea, along with other CTX-M variants and plasmid-borne AmpC beta-lactamases such as DHA-1, CMY-2, CMY-10, and CMY-11.
CTX-M-14 and CTX-M-15 enzymes are the dominant type of extended-spectrum beta-lactamase in clinical isolates of Escherichia coli from Korea.
The study identifies CTX-M-14 and CTX-M-15 as the dominant extended-spectrum beta-lactamases in clinical isolates of Escherichia coli in Korea, along with other CTX-M variants and plasmid-borne AmpC beta-lactamases such as DHA-1, CMY-2, CMY-10, and CMY-11.
Emergence of CTX-M-3, TEM-1 and a new plasmid-mediated MOX-4 AmpC in a multiresistant Aeromonas caviae isolate from a patient with pneumonia.
The study reports the emergence of CTX-M-3, TEM-1, and a novel plasmid-mediated MOX-4 AmpC beta-lactamase in a multidrug-resistant Aeromonas caviae isolate from a pneumonia patient, conferring resistance to various β-lactam antibiotics.
Emergence of CTX-M-3, TEM-1 and a new plasmid-mediated MOX-4 AmpC in a multiresistant Aeromonas caviae isolate from a patient with pneumonia.
Emergence of CTX-M-3, TEM-1 and a new plasmid-mediated MOX-4 AmpC in a multiresistant Aeromonas caviae isolate from a patient with pneumonia.
Emergence of CTX-M-3, TEM-1 and a new plasmid-mediated MOX-4 AmpC in a multiresistant Aeromonas caviae isolate from a patient with pneumonia.
Emergence of CTX-M-3, TEM-1 and a new plasmid-mediated MOX-4 AmpC in a multiresistant Aeromonas caviae isolate from a patient with pneumonia.
Laboratory surveillance for prospective plasmid-mediated AmpC beta-lactamases in the Kinki region of Japan.
The study identified plasmid-mediated AmpC beta-lactamases (PABLs) in various Enterobacteriaceae isolates, with CMY-2 being the most prevalent in E. coli, DHA-1 in K. pneumoniae, and MOX-1 in K. oxytoca.
CMY-2, CMY-8b, and DHA-1 plasmid-mediated AmpC β-lactamases among clinical isolates of Escherichia coli and Klebsiella pneumoniae from a university hospital, Thailand.
CMY-2, CMY-8b, and DHA-1 plasmid-mediated AmpC β-lactamases among clinical isolates of Escherichia coli and Klebsiella pneumoniae from a university hospital, Thailand.
CMY-2, CMY-8b, and DHA-1 plasmid-mediated AmpC β-lactamases among clinical isolates of Escherichia coli and Klebsiella pneumoniae from a university hospital, Thailand.
Bacteremia due to extended-spectrum-β-lactamase-producing Aeromonas spp. at a medical center in Southern Taiwan.
Bacteremia due to extended-spectrum-β-lactamase-producing Aeromonas spp. at a medical center in Southern Taiwan.
Bacteremia due to extended-spectrum-β-lactamase-producing Aeromonas spp. at a medical center in Southern Taiwan.
Crystal structure of Mox-1, a unique plasmid-mediated class C beta-lactamase with hydrolytic activity towards moxalactam.
The study characterizes Mox-1, a plasmid-mediated class C beta-lactamase with hydrolytic activity towards moxalactam, cephalothin, and extended-spectrum cephalosporins, providing insights into its unique substrate profile and structural features.
Genotypic Identification of AmpC beta-lactamases Production in Gram-Negative Bacilli Isolates.
The study identified plasmid-mediated AmpC beta-lactamase genes (MOX, FOX, EBC, and CIT) in Gram-negative bacilli isolates, highlighting the importance of molecular detection methods for accurate identification of AmpC producers.
Characterization of Plasmid-Mediated AmpC and Carbapenemases among Iranian Nosocomial Isolates of Klebsiella pneumoniae Using Phenotyping and Genotyping Methods.
The study identified plasmid-mediated AmpC beta-lactamases (blaMOX, blaCIT) and carbapenemases (blaVIM, blaGES) in clinical isolates of Klebsiella pneumoniae in Iran, highlighting the high prevalence of these resistance mechanisms.
OXA-372, a novel carbapenem-hydrolysing class D β-lactamase from a Citrobacter freundii isolated from a hospital wastewater plant.
OXA-372, a novel carbapenem-hydrolysing class D β-lactamase from a Citrobacter freundii isolated from a hospital wastewater plant.
Cooccurrence of Multiple AmpC beta-lactamases in Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis in Tunisia.
The study identifies multiple AmpC beta-lactamase genes, including bla CMY-4, bla CMY-16, bla FOX-3, and bla MOX-2, in clinical isolates of Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis in Tunisia, highlighting the coexistence of these resistance genes in a single strain.
Characterization of ceftriaxone-resistant Aeromonas spp. isolates from stool samples of both children and adults in Southern India.
The study identified blaCTX-M and MOX genes as the primary mechanisms of ceftriaxone resistance in Aeromonas spp. isolates from stool samples in Southern India.
Genome-based insights into the resistome and mobilome of multidrug-resistant Aeromonas sp. ARM81 isolated from wastewater.
The study identified multiple AMR genes in Aeromonas sp. ARM81, including three aminoglycoside resistance genes (aph(3'-VIb), aph(3''-Ib), and aph(6)-Id), a tetracycline efflux gene (tetA(E)), and two beta-lactamase genes (blaPER-1 and blaMOX-12).
Resistance to antimicrobial drugs in different surface waters and wastewaters of Guadeloupe.
The study identified several AMR genes including blaCTX-M, blaSHV, blaTEM, qnrB19, qnrB1, aac(6')-Ib-cr, VEB-1, CMY-2, and CMY-8 in Enterobacteriaceae isolates from surface waters and wastewaters in Guadeloupe. These genes conferred resistance to various antibiotics such as ceftazidime, cefotaxime, ampicillin, ciprofloxacin, gentamicin, and cefoxitin.
Co-Occurrence of Plasmid-Mediated AmpC beta-lactamase Activity Among Klebsiella pneumoniae and Escherichia Coli.
The study identified plasmid-mediated AmpC beta-lactamase genes, including bla CMY, bla MOX, bla DHA, and bla EBC, in Klebsiella pneumoniae and Escherichia coli isolates from Libya. These genes conferred resistance to cefoxitin and cefepime.
Functional Repertoire of Antibiotic Resistance Genes in Antibiotic Manufacturing Effluents and Receiving Freshwater Sediments.
The study identified numerous antibiotic resistance genes (ARGs) in antibiotic manufacturing effluents and receiving sediments, highlighting the presence of both known and potentially novel resistance mechanisms. Key findings include the discovery of macrolide resistance genes such as hflx, msr(e), mph(e), mph(g), and mef(c), as well as sulfonamide resistance genes sul1 and sul2, and beta-lactamase genes like bla ges-1, bla veb-9, and bla cm y-10. Additionally, trimethoprim resistance genes dfr14, dfra1, and dfr17 were identified.
Functional Repertoire of Antibiotic Resistance Genes in Antibiotic Manufacturing Effluents and Receiving Freshwater Sediments.
The study identified numerous antibiotic resistance genes (ARGs) in antibiotic manufacturing effluents and receiving sediments, highlighting the presence of both known and potentially novel resistance mechanisms. Key findings include the discovery of macrolide resistance genes such as hflx, msr(e), mph(e), mph(g), and mef(c), as well as sulfonamide resistance genes sul1 and sul2, and beta-lactamase genes like bla ges-1, bla veb-9, and bla cm y-10. Additionally, trimethoprim resistance genes dfr14, dfra1, and dfr17 were identified.
Aeromonas caviae mimicking Vibrio cholerae infectious enteropathy in a cholera-endemic region with possible public health consequences: two case reports.
The study identified Aeromonas caviae causing cholera-like symptoms, which was initially mistaken for Vibrio cholerae. The isolates carried genes encoding resistance to beta-lactam, sulfonamide, and trimethoprim.
Poultry hatcheries as potential reservoirs for antimicrobial-resistant Escherichia coli: A risk to public health and food safety.
The study identified several beta-lactam resistance genes, including bla TEM, bla SHV, bla OXA-1, bla MOX-like, bla CIT-like, and bla FOX, in Escherichia coli isolates from poultry hatcheries, highlighting the potential of hatcheries as reservoirs of antimicrobial-resistant bacteria.
Poultry hatcheries as potential reservoirs for antimicrobial-resistant Escherichia coli: A risk to public health and food safety.
The study identified several beta-lactam resistance genes, including bla TEM, bla SHV, bla OXA-1, bla MOX-like, bla CIT-like, and bla FOX, in Escherichia coli isolates from poultry hatcheries, highlighting the potential of hatcheries as reservoirs of antimicrobial-resistant bacteria.
Faecal colonization of E. coli and Klebsiella spp. producing extended-spectrum beta-lactamases and plasmid-mediated AmpC in Mozambican university students.
The study identified various extended-spectrum beta-lactamase (ESBL) and plasmid-mediated AmpC (pAmpC) genes, including bla CTX-M-15, bla CTX-M-55, bla CTX-M-3, bla CTX-M-186, bla DHA, bla MOX, bla FOX, and bla CMY, in E. coli and Klebsiella spp. isolates from Mozambican university students.
Antimicrobial Resistance in ESBL-Producing E. coli Isolates from Companion Animals
The study identifies several novel beta-lactamase genes, including bla_SFO, bla_Cph, bla_VIM, bla_Act, bla_MIR, bla_MOX, and bla_PAO, along with commonly encountered genes like bla_CTX-M-15, bla_TEM-1B, and bla_OXA-1, in ESBL-producing E. coli isolates from companion animals.
Antimicrobial resistance of Escherichia coli and Enterococcus spp. isolated from Estonian cattle and swine from 2010 to 2015.
The study identified bla CMY-1, bla CMY-2, and bla TEM-52C genes in E. coli isolates from Estonian cattle and swine, indicating resistance to beta-lactam antibiotics. High levels of resistance to various antibiotics were observed in E. coli and Enterococcus spp. from both animal sources.
Characterization of Antimicrobial Resistance in Serratia spp. and Citrobacter spp. Isolates from Companion Animals in Japan: Nosocomial Dissemination of Extended-Spectrum Cephalosporin-Resistant Citrobacter freundii.
The study identified bla CTX-M-3, bla CMY-1, and bla DHA-1 as the primary mechanisms of extended-spectrum cephalosporin resistance in Citrobacter spp. isolates from companion animals in Japan.
Screening of antibiotic resistance genes in pathogenic bacteria isolated from tiny freshwater shrimp (Macrobrachium lanchesteri) and "Kung Ten", the uncooked Thai food.
The study identified several antibiotic resistance genes, including MOX, ACC, bla CTX-M, and Int1, in pathogenic bacteria isolated from freshwater shrimp and Kung Ten salad, indicating potential risks for foodborne diseases.
Co-Occurrence of the bla (KPC-2) and Mcr-3.3 Gene in Aeromonas caviae SCAc2001 Isolated from Patients with Diarrheal Disease.
The study identifies multiple antimicrobial resistance genes in Aeromonas caviae SCAc2001, including blaKPC, mcr-3.3, and others, highlighting the potential public health risks posed by this strain.
Homology analysis between clinically isolated extraintestinal and enteral Klebsiella pneumoniae among neonates.
The study identified various beta-lactamase genes, including SHV, TEM-1, CTX-M-1, CTX-M-14, CTX-M-15, CMY-8, and NDM-1, which confer resistance to multiple antibiotics in Klebsiella pneumoniae isolates from neonates.
Taxonomy, virulence determinants and antimicrobial susceptibility of Aeromonas spp. isolated from bacteremia in southeastern China.
The study identified several beta-lactamase genes (blaTEM, blaSHV, blaAQU-1, blaMOX, blaCepH, blaCphA) and the aac(6')-Ib-cr gene associated with antimicrobial resistance in Aeromonas isolates from bacteremia cases in southeastern China.
Evaluation of Two Phenotypic Methods for the Detection of Plasmid-Mediated AmpC beta-lactamases among Enterobacteriaceae Isolates.
The study evaluated two phenotypic methods for detecting plasmid-mediated AmpC beta-lactamases in Enterobacteriaceae isolates and identified several plasmid-mediated AmpC genes including ACC, FOX, MOX, DHA, CIT, and EBC using multiplex PCR.
Molecular detection of plasmid-derived AmpC β-lactamase among clinical strains of Enterobacteriaceae in Bahrain.
The study identifies plasmid-mediated AmpC β-lactamase genes (ACC, FOX, MOX, DHA, CIT, EBC) in clinical isolates of Enterobacteriaceae in Bahrain, highlighting their association with multidrug resistance.
Extended-Spectrum β-Lactam Resistant Klebsiella pneumoniain and Escherichia coli in Wild European Hedgehogs (Erinaceus europeus) Living in Populated Areas.
The study identified several β-lactamase resistance genes, including bla CTX-M-15, bla SHV-28, bla CMY-1, bla CMY-2, and bla OXA-48, in extended-spectrum β-lactam-resistant Klebsiella pneumoniae and Escherichia coli isolated from wild European hedgehogs in Catalonia, Spain.
Insights Into the Inhibition of MOX-1 beta-lactamase by S02030, a Boronic Acid Transition State Inhibitor.
The study characterizes the inhibition of MOX-1 beta-lactamase by S02030, a boronic acid transition state inhibitor, showing that S02030 reduces MICs of ceftazidime, cefepime, and cefoxitin in E. coli expressing MOX-1.
Prevalence of ESBL and AmpC genes in E. coli isolates from urinary tract infections in the north of Iran.
The study identified the prevalence of ESBL and AmpC genes in E. coli isolates from urinary tract infections in the north of Iran, highlighting the significant presence of blaSHV, blaTEM, blaCTX-M, MOX, EBC, and CIT genes.
Resistance Patterns, mcr-4 and OXA-48 Genes, and Virulence Factors of Escherichia coli from Apennine Chamois Living in Sympatry with Domestic Species, Italy.
The study identified the colistin resistance gene mcr-4 and carbapenems resistance gene OXA-48 in Escherichia coli isolates from wild and domestic ungulates in Italy, highlighting the presence of these resistance mechanisms in wildlife.
Class C beta-lactamases: Molecular Characteristics.
The paper characterizes various class C beta-lactamases, highlighting their molecular characteristics, resistance profiles, and genetic variations. Key findings include the identification of specific genes such as blaACC-1, blaACT-1, blaADC-1, blaCMY-2, blaFOX-1, blaMOX-1, and blaPDC-1, along with their roles in conferring resistance to various β-lactam antibiotics.
Class C β-Lactamases: Molecular Characteristics.
Class C β-Lactamases: Molecular Characteristics.
KPC-3-, GES-5-, and VIM-1-Producing Enterobacterales Isolated from Urban Ponds.
The study identified bla KPC-3, bla GES-5, and bla VIM genes in various Enterobacterales isolates from urban ponds, highlighting their role in carbapenem resistance.
Detection of Klebsiella pneumoniae antibiotic-resistant genes: An impending source of multidrug resistance dissemination through raw food.
The study identified several β-lactamase genes, including bla CTX-M, bla SHV, bla TEM, bla MOX, bla FOX, and carbapenemase genes such as bla NDM, bla IMP, bla VIM, and bla OXA-48, in Klebsiella pneumoniae isolates from raw food samples, highlighting the potential for multidrug resistance dissemination through the food chain.
Emergence and Evolution of Unique Plasmids Harboring bla(IMP-70) and bla(CTX-M-253) in Multidrug-Resistant Providencia rettgeri.
The study identifies bla(IMP-70) and bla(CTX-M-253) as novel beta-lactamase genes in multidrug-resistant Providencia rettgeri, highlighting their role in carbapenem and cephalosporin resistance.
Molecular and Kinetic Characterization of MOX-9, a Plasmid-Mediated Enzyme Representative of a Novel Sublineage of MOX-Type Class C beta-lactamases.
The study characterizes MOX-9, a plasmid-mediated class C beta-lactamase from Citrobacter freundii, which shows distinct kinetic properties and resistance to certain cephalosporins.
Antibiotic Susceptibility Profiles and Resistance Mechanisms to β-Lactams and Polymyxins of Escherichia coli from Broilers Raised under Intensive and Extensive Production Systems.
The study identifies several β-lactamase genes, including SHV-12, CTX-M group variants, TEM, OXA, and PMAβ, as well as the mcr-1 gene responsible for polymyxin resistance in E. coli isolates from broilers raised in intensive and extensive systems. The prevalence of reduced susceptibility to antibiotics is higher in isolates from the intensive system.
Aeromonas species isolated from aquatic organisms, insects, chicken, and humans in India show similar antimicrobial resistance profiles.
The study identified multiple antimicrobial resistance (AMR) genes in Aeromonas species isolated from various hosts in India, including beta-lactamases (bla OXA-12, bla OXA-427, bla OXA-724, bla OXA-780, bla FOX-2, bla FOX-4, bla FOX-5, bla FOX-7, bla AQU-2, bla MOX-7), metallo-beta-lactamases (cphA3, cphA4, cphA5, cphA8, ImiH), and other resistance genes (dfrA12, aadA2, ANT(3")-IIa, sul1). Additionally, multidrug efflux pump genes (mdtH, zntA, emrD, blR, crp) were found to contribute to AMR in these isolates.
Aeromonas species isolated from aquatic organisms, insects, chicken, and humans in India show similar antimicrobial resistance profiles.
The study identified multiple antimicrobial resistance (AMR) genes in Aeromonas species isolated from various hosts in India, including beta-lactamases (bla OXA-12, bla OXA-427, bla OXA-724, bla OXA-780, bla FOX-2, bla FOX-4, bla FOX-5, bla FOX-7, bla AQU-2, bla MOX-7), metallo-beta-lactamases (cphA3, cphA4, cphA5, cphA8, ImiH), and other resistance genes (dfrA12, aadA2, ANT(3")-IIa, sul1). Additionally, multidrug efflux pump genes (mdtH, zntA, emrD, blR, crp) were found to contribute to AMR in these isolates.
Detection of AmpC beta-lactamases in gram-negative bacteria.
The study established a multiplex PCR method to detect six families of AmpC beta-lactamase genes (ACC, EBC, CIT, DHA, MOX, and FOX) in gram-negative bacteria, demonstrating high sensitivity and specificity.
Expanded catalogue of metagenome-assembled genomes reveals resistome characteristics and athletic performance-associated microbes in horse.
The study identified a diverse array of antibiotic resistance genes (ARG) in the horse gut microbiome, highlighting the widespread use of antibiotics in horse management. The resistome characteristics were analyzed alongside the identification of microbes associated with athletic performance.
Development of Nanobodies as Theranostic Agents against CMY-2-Like Class C β-Lactamases.
The study identifies three nanobodies (cAb CMY-2 (250), cAb CMY-2 (254), and cAb CMY-2 (272)) that specifically bind to CMY-2 β-lactamase, with cAb CMY-2 (254) showing the highest stability and affinity. These nanobodies act as noncompetitive inhibitors of CMY-2 activity and are used to develop a highly specific sandwich ELISA for detecting CMY-2-producing bacteria.
Epidemiological characteristics, virulence potential, antimicrobial resistance profiles, and phylogenetic analysis of Aeromonas caviae isolated from extra-intestinal infections.
The study identified multiple antimicrobial resistance genes in Aeromonas caviae isolates from extra-intestinal infections, including blaMOX, blaPER-3, blaOXA, blaNDM, blaCphA, qnrS2, qnrVC, aac(6')-Ib-cr, tet(A), tet(E), tet(31), dfrA1, dfrA12, dfrA14, dfrA15b, floR, catB3, catII, and catI, which confer resistance to various antibiotics such as cephalosporins, carbapenems, fluoroquinolones, tetracyclines, trimethoprim, and chloramphenicol.
Characterization of Third Generation Cephalosporin- and Carbapenem-Resistant Aeromonas Isolates from Municipal and Hospital Wastewater.
The study identified several carbapenemase and ESBL genes in Aeromonas isolates from wastewater, highlighting the presence of bla KPC-2, bla VIM-2, bla OXA-48, bla IMP-13, bla GES-5, and bla MOX as significant contributors to antibiotic resistance.
Detection of Virulence and β-lactamase resistance genes of non-typhoidal Salmonella isolates from human and animal origin in Egypt "one health concern".
The study detected blaOXA-2 and blaCMY-1 genes in non-typhoidal Salmonella isolates from human and animal origins in Egypt, indicating the presence of β-lactamase resistance mechanisms.
Phenotypic and Genotypic Characteristics of Antimicrobial Resistance in Citrobacter freundii Isolated from Domestic Ducks (Anas platyrhynchos domesticus) in Bangladesh.
The study identified multiple AMR genes in Citrobacter freundii isolates from domestic ducks in Bangladesh, including beta-lactamases (bla TEM-1, bla CMY-2, bla CMY-9, bla CTX-M-14), sulfonamide resistance genes (sul1, sul2), tetracycline resistance genes (tetA, tetB), fluoroquinolone resistance genes (qnrA, qnrB, qnrS), and an aminoglycoside resistance gene (aacC4).
The carbapenem inoculum effect provides insight into the molecular mechanisms underlying carbapenem resistance in Enterobacterales.
The study identified that various carbapenemase genes, including blaKPC-3, blaSME-2, blaIMP-4, blaNDM-1, blaVIM-27, blaCMY-10, and blaOXA-48, confer a meropenem inoculum effect when expressed in E. coli K-12. These genes were experimentally validated to show increased resistance with higher inocula.
Whole genome sequence analysis of Aeromonas spp. isolated from ready-to-eat seafood: antimicrobial resistance and virulence factors.
The study identified various AMR genes in Aeromonas strains isolated from ready-to-eat seafood, including beta-lactamases (bla OXA-12, bla OXA-780, bla OXA-427, bla OXA-956, cphA1, cphA2, cphA5), quinolone resistance gene qnrS2, sulfonamide resistance gene sul1, aminoglycoside resistance gene aadA1, tetracycline efflux pump tet(E), and efflux pump qacEΔ1.
Whole genome sequence analysis of Aeromonas spp. isolated from ready-to-eat seafood: antimicrobial resistance and virulence factors.
The study identified various AMR genes in Aeromonas strains isolated from ready-to-eat seafood, including beta-lactamases (bla OXA-12, bla OXA-780, bla OXA-427, bla OXA-956, cphA1, cphA2, cphA5), quinolone resistance gene qnrS2, sulfonamide resistance gene sul1, aminoglycoside resistance gene aadA1, tetracycline efflux pump tet(E), and efflux pump qacEΔ1.
Characterization of Beta-Lactam Resistome of Escherichia coli Causing Nosocomial Infections.
The study characterized the beta-lactam resistome of Escherichia coli causing nosocomial infections, identifying several beta-lactamase genes including blaTEM, blaCTX, blaSHV, blaBIL, blaDHA, blaCMY, blaIMP, blaLAP, blaP, blaVIM, and blaKPC, which confer resistance to various beta-lactam antibiotics.
Analyses of Extended-Spectrum-β-Lactamase, Metallo-β-Lactamase, and AmpC-β-Lactamase Producing Enterobacteriaceae from the Dairy Value Chain in India.
The study identified several β-lactamase genes, including bla CMY, bla MOX, bla FOX, bla EBC, bla DHA, bla CTX-M1, bla SHV, bla TEM, bla VIM, bla IMP, bla SPM, bla SIM, and bla GIM, in Enterobacteriaceae isolates from milk samples in India, highlighting the presence of multidrug-resistant bacteria in the dairy value chain.
Antimicrobial resistance in aeromonads and new therapies targeting quorum sensing.
The paper discusses the prevalence of antimicrobial resistance in Aeromonas species, highlighting the presence of various beta-lactamase genes such as blaTEM-24, blaIMP-19, blaVIM-4, blaKPC-2, blaNDM-1, blaVIM-2, blaOXA-48, blaIMP-13, blaGES-5, blaTEM-1, blaSHV-12, blaVEB-9, blaMOX, blaFOX, blaACC, and others. It also identifies genes like cphA, vat, mcr-3.41, mcr-7.1, sul, dfr, tetA, rsmA, and adeF associated with resistance to sulfonamides, trimethoprim, tetracycline, polymyxin, and other antibiotics. The study emphasizes the role of horizontal gene transfer and mobile genetic elements in the dissemination of these resistance genes.
Emergence and clonal expansion of Aeromonas hydrophila ST1172 that simultaneously produces MOX-13 and OXA-724.
The study identifies the emergence of a novel carbapenem-resistant Aeromonas hydrophila sequence type (ST1172) that simultaneously produces MOX-13 and OXA-724 beta-lactamases, leading to resistance against multiple beta-lactam antibiotics.
Genomic analysis of clinical Aeromonas isolates reveals genetic diversity but little evidence of genetic determinants for diarrhoeal disease.
The study identifies a high prevalence of antimicrobial resistance (AMR) genes in Aeromonas isolates from children with moderate-to-severe diarrhea (MSD) in Karachi, Pakistan. Key AMR genes include beta-lactamases (blaCMY-1, oxa-12, cphA2, mox), sulfonamide resistance (sul1), aminoglycoside resistance (aac(6')-lld), and tetracycline resistance (tetE).
Genomic analysis of clinical Aeromonas isolates reveals genetic diversity but little evidence of genetic determinants for diarrhoeal disease.
The study identifies a high prevalence of antimicrobial resistance (AMR) genes in Aeromonas isolates from children with moderate-to-severe diarrhea (MSD) in Karachi, Pakistan. Key AMR genes include beta-lactamases (blaCMY-1, oxa-12, cphA2, mox), sulfonamide resistance (sul1), aminoglycoside resistance (aac(6')-lld), and tetracycline resistance (tetE).
High prevalence of multidrug-resistant Enterobacterales carrying extended-spectrum beta-lactamase and AmpC genes isolated from neonatal sepsis in Ahvaz, Iran.
The study identified a high prevalence of multidrug-resistant Enterobacterales carrying extended-spectrum beta-lactamase (ESBL) and AmpC genes, with bla CTX-M−15 being the most common ESBL gene.
Assessment of three antibiotic combination regimens against Gram-negative bacteria causing neonatal sepsis in low- and middle-income countries.
The study identifies multiple AMR genes and mutations in Gram-negative bacteria causing neonatal sepsis in LMICs, including ESBLs, carbapenemases, and aminoglycoside-modifying enzymes, highlighting the high prevalence of multidrug resistance and the need for effective antibiotic combinations.
Rumi and Pasteurized Kareish Cheeses Are a Source of β-Lactam-Resistant Salmonella in the Nile Delta Region of Egypt: Insights into Their Incidence, AMR Pattern, Genotypic Determinants of Virulence and β-Lactam Resistance.
The study identifies several β-lactam resistance genes, including bla OXA-1, bla OXA-2, bla TEM-1, bla CTX-M, bla CMY-1, and bla CMY-2, in β-lactam-resistant Salmonella isolates from Rumi and pasteurized Kareish cheeses in the Nile Delta region of Egypt.
Relative inhibitory activities of newly developed diazabicyclooctanes, boronic acid derivatives, and penicillin-based sulfone beta-lactamase inhibitors against broad-spectrum AmpC beta-lactamases.
The study evaluates the inhibitory activities of various beta-lactamase inhibitors against a wide range of AmpC beta-lactamases, identifying the effectiveness of certain inhibitors like durlobactam and zidebactam in reducing the MIC values of β-lactam antibiotics against AmpC-producing strains.
Epidemiology and Molecular Characterisation of Multidrug-Resistant Escherichia coli Isolated from Cow Milk.
The study identified several AMR genes in multidrug-resistant E. coli isolates from cow milk, including bla TEM, bla CTX-M, bla OXA-1, bla OXA-2, bla CMY-1, tet A, tet B, tet D, sul -1, and sul -2, which confer resistance to various antibiotics.
Whole-genome sequencing-based species classification, multilocus sequence typing, and antibiotic resistance mechanisms of the clinical Aeromonas complex.
The study identified multiple beta-lactamase genes, including bla NDM-1, bla PER-3, and bla OXA-1, along with other resistance genes such as aac(6′)-Ib-cr6, aph(3″)-Ib, and floR, which contribute to resistance against various antibiotics in Aeromonas isolates.
Wild Birds as Drivers of Salmonella Braenderup and Multidrug Resistant Bacteria in Wetlands of Northern Italy.
The study identifies several AMR genes in bacterial isolates from wild aquatic birds in Northern Italy, including beta-lactamases (blaTEM, blaCMY-1, blaCMY-2, blaNDM, blaKPC), colistin resistance genes (mcr-2, mcr-3, mcr-4), tetracycline resistance genes (tetA, tetB, tetC, tetL, tetM, tetK), macrolide resistance genes (ermB, vatD, vgA, msrC), vancomycin resistance genes (vanC1, vanC2, vanM, vanG), sulfonamide resistance genes (sul1, sul2, sul3), aminoglycoside resistance genes (aac(3), aac(6')-Ib, aph(3')-Ia, armA, rmtB, rmtC, rmtF), and nitrofurantoin resistance genes (nfsA, nfsB).
Massive culture-based approach for the screening of AmpC, ESBL, and carbapenemase producers from rectal swabs.
The study presents a massive culture-based approach for the screening of AmpC, ESBL, and carbapenemase producers from rectal swabs, demonstrating improved specificity for detecting ESBL producers compared to conventional methods. It identifies various beta-lactamase genes, including bla CTX-M-1/2-like, bla CTX-M-8-like, bla CTX-M-9-like, bla SHV-like, bla TEM-like, bla GES-like, bla MOX, bla CIT, bla DHA, bla ACC, bla EBC, bla FOX, bla CMY-2, and bla NDM.
Prevalence and genetic characteristics of antimicrobial-resistant Escherichia coli in wild birds in Japan.
The study identified several AMR genes and mutations in E. coli isolates from wild birds in Japan, including bla CTX-M-14, bla CTX-M-15, bla CTX-M-55, bla MOX-4, bla CMY-2, qnrS1, qnrS2, and mutations in gyrA and parC that confer resistance to cefotaxime, nalidixic acid, and ciprofloxacin.
The carbapenem inoculum effect provides insights into the molecular mechanisms underlying carbapenem resistance in the Enterobacterales.
The study identified that various carbapenemase genes, including blaKPC-3, blaSME-2, blaIMP-4, blaNDM-1, blaVIM-27, blaCMY-10, and blaOXA-48, when expressed in E. coli, significantly increased meropenem MICs and exhibited an inoculum effect. These findings highlight the role of carbapenemases in carbapenem resistance and the importance of the inoculum effect in diagnosing carbapenemase-producing CRE.
Prevalence of ESBL-Producing Escherichia coli on Neck Skin in Slaughtered Broilers Raised on Conventional, Antibiotic-Free, and Organic Farms.
The study identified various ESBL and AmpC genes, including bla CTX-M-1, bla CTX-M-9, bla TEM, bla SHV, bla OXA, bla CIT, bla MOX, bla DHA, bla ACC, bla EBC, and bla FOX, in ESBL-producing E. coli isolates from broiler neck skin. These genes were associated with resistance to beta-lactam antibiotics such as cefotaxime, ceftazidime, and cefoxitin.
Characterization of a plasmid-borne and constitutively expressed blaMOX-1 gene encoding AmpC-type beta-lactamase.
Characterization of a plasmid-borne and constitutively expressed blaMOX-1 gene encoding AmpC-type beta-lactamase.
Characterization of a plasmid-borne and constitutively expressed blaMOX-1 gene encoding AmpC-type beta-lactamase.
Characterization of a plasmid-borne and constitutively expressed blaMOX-1 gene encoding AmpC-type beta-lactamase.
Comparative characterization of the cephamycinase blaCMY-1 gene and its relationship with other beta-lactamase genes.
Comparative characterization of the cephamycinase blaCMY-1 gene and its relationship with other beta-lactamase genes.
Comparative characterization of the cephamycinase blaCMY-1 gene and its relationship with other beta-lactamase genes.
Comparative characterization of the cephamycinase blaCMY-1 gene and its relationship with other beta-lactamase genes.
No comments yet. Be the first to comment!