Browse AMR Genes

Explore antimicrobial resistance genes from the literature

blaOXA-23

OXA carbapenemase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to blaOXA-23

Browse AMR rules for blaOXA-23

Overview

Drug Classes: carbapenems
Papers: 2
Mutations: 2

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
H121R	-	-	-	carbapenems	Reslit	Candidate
V128L	GTT -> TTG	-	-	carbapenems	Reslit	Candidate

Papers2

1

Antibiotic resistance in Pakistan: a systematic review of past decade.

PMID 33676421 · 2021

Mutation Information

blaOXA-23: p.H121R

Protein Change: H121R
Confers Resistance To: carbapenems
Source Database: Reslit

2

Analysis of β-lactone formation by clinically observed carbapenemases informs on a novel antibiotic resistance mechanism.

PMID 32963107 · 2020

Clinically observed variant OXA-23 V128L

Mutation Information

blaOXA-23: p.V128L / c.GTT -> TTG

Protein Change: V128L
Nucleotide Change: GTT -> TTG
Confers Resistance To: carbapenems
Validation Method: kinetic and product studies
Source Database: Reslit