blaOXA-499

carbapenem-hydrolyzing class D beta-lactamase

Overview

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
-	A-14G	-	Acinetobacter pittii, Acinetobacter baumannii	carbapenems	Reslit	Candidate
-	G-42A	-	Acinetobacter pittii, Acinetobacter baumannii	carbapenems	Reslit	Candidate

Papers1

Phenotypic Variation and Carbapenem Resistance Potential in OXA-499-Producing Acinetobacter pittii.

Mutations in the promoter region of blaOXA-499 were identified in CAB009 and CAB010.

Nucleotide Change: A-14G, G-42A
Organisms: Acinetobacter pittii, Acinetobacter baumannii
Confers Resistance To: carbapenems
Validation Method: whole-genome sequencing and PCR; RT-qPCR and RNA-Seq analysis; whole-genome sequencing and promoter sequence analysis
Source Database: Reslit