Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
subclass B3 metallo-beta-lactamase PAM-5
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| blaPAM-5 | Card DatabaseReference Gene Catalog | 2 | CARBAPENEM | Pseudomonas tohonis | - | - | PP331844.1 | WVW91709.1 |
| blaPAM-6 | Reference Gene Catalog | 1 | CARBAPENEM | Pseudomonas sp. | - | - | PV075092.1 | XOU30561.1 |
| blaPAM-7 | Reference Gene Catalog | 1 | CARBAPENEM | Pseudomonas solani | - | - | PX504250.1 | YBW81178.1 |
| blaPAM-2 | Card DatabaseReference Gene CatalogReslit | 4 | CARBAPENEM, carbapenems | Pseudomonas tohonis +1 | Europe|United States | 2021, 2025 | BQKM01000003.1 | GJN52392.1 |
| blaPAM-1 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 5 | MEROPENEM, ERTAPENEM +14 | Aquipseudomonas alcaligenes +1 | Europe|United States | 2014, 2025 | AB858498.1 | BAO01151.1 |
| blaPAM-3 | Card DatabaseReference Gene Catalog | 2 | CARBAPENEM | Pseudomonas tohonis | - | 2022 | BQKL01000042.1 | GJN50066.1 |
A subclass B3 metallo-β-lactamase found in Pseudomonas alcaligenes.
A subclass B3 metallo-β-lactamase found in Pseudomonas alcaligenes.
A subclass B3 metallo-β-lactamase found in Pseudomonas alcaligenes.
A subclass B3 metallo-β-lactamase found in Pseudomonas alcaligenes.
Complete whole-genome sequence of the novel Pseudomonas species strain TUM18999, isolated from a patient with a burn wound in Japan.
Complete whole-genome sequence of the novel Pseudomonas species strain TUM18999, isolated from a patient with a burn wound in Japan.
Molecular and biochemical characterization of novel PAM-like MBL variants, PAM-2 and PAM-3, from clinical isolates of Pseudomonas tohonis.
Molecular and biochemical characterization of novel PAM-like MBL variants, PAM-2 and PAM-3, from clinical isolates of Pseudomonas tohonis.
Establishing Clinical and Laboratory Standards Institute M45 antimicrobial susceptibility testing methods and breakpoints for Pseudomonas other than Pseudomonas aeruginosa.
The study established tentative CLSI M45 antimicrobial susceptibility testing breakpoints for Pseudomonas other than Pseudomonas aeruginosa (POPA). It identified various beta-lactamase genes, including metallo-beta-lactamases (MBLs) such as bla POM-1, bla POM-2, bla PAM-1, bla PST-1, bla VIM-2, bla CARB-2, bla DHA-1, and bla IMP-13, which confer resistance to carbapenems. Additionally, multidrug-resistant efflux pumps like ttgABC and tmexCD-toprJ were found to contribute to carbapenem resistance. Other resistance genes for aminoglycosides, trimethoprim-sulfamethoxazole, quaternary ammonium compounds, chloramphenicol, and fluoroquinolones were also detected.
Establishing Clinical and Laboratory Standards Institute M45 antimicrobial susceptibility testing methods and breakpoints for Pseudomonas other than Pseudomonas aeruginosa.
The study established tentative CLSI M45 antimicrobial susceptibility testing breakpoints for Pseudomonas other than Pseudomonas aeruginosa (POPA). It identified various beta-lactamase genes, including metallo-beta-lactamases (MBLs) such as bla POM-1, bla POM-2, bla PAM-1, bla PST-1, bla VIM-2, bla CARB-2, bla DHA-1, and bla IMP-13, which confer resistance to carbapenems. Additionally, multidrug-resistant efflux pumps like ttgABC and tmexCD-toprJ were found to contribute to carbapenem resistance. Other resistance genes for aminoglycosides, trimethoprim-sulfamethoxazole, quaternary ammonium compounds, chloramphenicol, and fluoroquinolones were also detected.
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