blaPAU

class A beta-lactamase PAU-1

Validation StatusConfirmed2+ DBs

Overview

Mechanism: Enzymatic modification
Validation Method: cloning in E. coli and P. aeruginosa followed by MIC testing
Drug Classes: BETA-LACTAM, AMOXICILLIN, AMPICILLIN, PIPERACILLIN, ampicillin, piperacillin, ceftriaxone, cefepime
Organisms: Pseudomonas aeruginosa, Escherichia coli
Geographic Location: China
Papers: 1
Databases: Card DatabaseReference Gene CatalogResFinder DatabaseReslit

Papers1

PMID N/A

Gene Information

Gene Name: blaPAU
Allele: blaPAU-1
Encodes: class A beta-lactamase PAU-1
Source Database: Reference Gene Catalog
Mechanism: Enzymatic modification
Confers Resistance To: BETA-LACTAMAMOXICILLINAMPICILLINPIPERACILLIN
Organisms Tested In: • Pseudomonas aeruginosa
Sequence Accession: KU881625.1
Protein Accession: APC57487.2
Notes: ARO:3006964

PMID N/A

Gene Information

Gene Name: blaPAU
Allele: blaPAU-1
Encodes: class A beta-lactamase PAU-1
Source Database: ResFinder Database
Mechanism: Enzymatic modification
Confers Resistance To: BETA-LACTAMAMOXICILLINAMPICILLINPIPERACILLIN
Organisms Tested In: • Pseudomonas aeruginosa
Sequence Accession: KU881625.1
Protein Accession: APC57487.2
Notes: ARO:3006964

PMID N/A

Gene Information

Gene Name: blaPAU
Allele: blaPAU-1
Encodes: class A beta-lactamase PAU-1
Source Database: Card Database
Mechanism: Enzymatic modification
Confers Resistance To: BETA-LACTAMAMOXICILLINAMPICILLINPIPERACILLIN
Organisms Tested In: • Pseudomonas aeruginosa
Sequence Accession: KU881625.1
Protein Accession: APC57487.2
Notes: ARO:3006964

PMID N/A

Gene Information

Gene Name: blaPAU
Allele: blaPAU-1
Encodes: PAU beta-lactamase
Source Database: Card Database
Mechanism: antibiotic inactivation
Organisms Tested In: • Pseudomonas aeruginosa
Sequence Accession: NG_065882.1
Protein Accession: WP_148044424.1
Notes: ARO:3006964

PAU-1, a Novel Plasmid-Encoded Ambler Class A beta-lactamase Identified in a Clinical Pseudomonas aeruginosa Isolate.

PMID 31824180 · 2019

The study identifies a novel plasmid-encoded Ambler class A beta-lactamase, blaPAU-1, which confers resistance to ampicillin, piperacillin, ceftriaxone, and cefepime in E. coli and P. aeruginosa.

Gene Information

Gene Name: blaPAU
Allele: blaPAU-1
Encodes: class A beta-lactamase
Source Database: Reslit
Mechanism: hydrolysis of β-lactam antibiotics
Confers Resistance To: ampicillinpiperacillinceftriaxonecefepime
Organisms Tested In: • Escherichia coli
• Pseudomonas aeruginosa
Geographic Location: China
Validation Method: cloning in E. coli and P. aeruginosa followed by MIC testing
Sequence Accession: MH053445

PAU-1, a Novel Plasmid-Encoded Ambler Class A β-Lactamase Identified in a Clinical Pseudomonas aeruginosa Isolate.

PMID 31824180 · 2019

Gene Information

Gene Name: blaPAU
Allele: blaPAU-1
Source Database: ResFinder Database
Mechanism: Enzymatic modification
Confers Resistance To: AMOXICILLINAMPICILLINPIPERACILLIN
Organisms Tested In: • Pseudomonas aeruginosa
Sequence Accession: MH053445

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blaPAU

class A beta-lactamase PAU-1

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to blaPAU

AMR Rules

Browse AMR rules for blaPAU

Validation StatusConfirmed2+ DBs

Overview

Mechanism: Enzymatic modification
Validation Method: cloning in E. coli and P. aeruginosa followed by MIC testing
Drug Classes: BETA-LACTAM, AMOXICILLIN, AMPICILLIN, PIPERACILLIN, ampicillin, piperacillin, ceftriaxone, cefepime
Organisms: Pseudomonas aeruginosa, Escherichia coli
Geographic Location: China
Papers: 1
Databases: Card DatabaseReference Gene CatalogResFinder DatabaseReslit

Papers1

PMID N/A

Gene Information

Gene Name: blaPAU
Allele: blaPAU-1
Encodes: class A beta-lactamase PAU-1
Source Database: Reference Gene Catalog
Mechanism: Enzymatic modification
Confers Resistance To: BETA-LACTAMAMOXICILLINAMPICILLINPIPERACILLIN
Organisms Tested In: • Pseudomonas aeruginosa
Sequence Accession: KU881625.1
Protein Accession: APC57487.2
Notes: ARO:3006964

PMID N/A

Gene Information

Gene Name: blaPAU
Allele: blaPAU-1
Encodes: class A beta-lactamase PAU-1
Source Database: ResFinder Database
Mechanism: Enzymatic modification
Confers Resistance To: BETA-LACTAMAMOXICILLINAMPICILLINPIPERACILLIN
Organisms Tested In: • Pseudomonas aeruginosa
Sequence Accession: KU881625.1
Protein Accession: APC57487.2
Notes: ARO:3006964

PMID N/A

Gene Information

Gene Name: blaPAU
Allele: blaPAU-1
Encodes: class A beta-lactamase PAU-1
Source Database: Card Database
Mechanism: Enzymatic modification
Confers Resistance To: BETA-LACTAMAMOXICILLINAMPICILLINPIPERACILLIN
Organisms Tested In: • Pseudomonas aeruginosa
Sequence Accession: KU881625.1
Protein Accession: APC57487.2
Notes: ARO:3006964

PMID N/A

Gene Information

Gene Name: blaPAU
Allele: blaPAU-1
Encodes: PAU beta-lactamase
Source Database: Card Database
Mechanism: antibiotic inactivation
Organisms Tested In: • Pseudomonas aeruginosa
Sequence Accession: NG_065882.1
Protein Accession: WP_148044424.1
Notes: ARO:3006964

PAU-1, a Novel Plasmid-Encoded Ambler Class A beta-lactamase Identified in a Clinical Pseudomonas aeruginosa Isolate.

PMID 31824180 · 2019

The study identifies a novel plasmid-encoded Ambler class A beta-lactamase, blaPAU-1, which confers resistance to ampicillin, piperacillin, ceftriaxone, and cefepime in E. coli and P. aeruginosa.

Gene Information

Gene Name: blaPAU
Allele: blaPAU-1
Encodes: class A beta-lactamase
Source Database: Reslit
Mechanism: hydrolysis of β-lactam antibiotics
Confers Resistance To: ampicillinpiperacillinceftriaxonecefepime
Organisms Tested In: • Escherichia coli
• Pseudomonas aeruginosa
Geographic Location: China
Validation Method: cloning in E. coli and P. aeruginosa followed by MIC testing
Sequence Accession: MH053445

PAU-1, a Novel Plasmid-Encoded Ambler Class A β-Lactamase Identified in a Clinical Pseudomonas aeruginosa Isolate.

PMID 31824180 · 2019

Gene Information

Gene Name: blaPAU
Allele: blaPAU-1
Source Database: ResFinder Database
Mechanism: Enzymatic modification
Confers Resistance To: AMOXICILLINAMPICILLINPIPERACILLIN
Organisms Tested In: • Pseudomonas aeruginosa
Sequence Accession: MH053445

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No comments yet. Be the first to comment!

blaPAU

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blaPAU

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