blaa1

View on PubMed

beta-lactamase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to blaa1

AMR Rules

Browse AMR rules for blaa1

Validation StatusCandidate

Overview

Validation Method: expression in E. coli and MIC testing
Drug Classes: penicillin, oxacillin, ampicillin, amoxicillin, cephalosporins, ceftriaxone, cefepime, meropenem, aztreonam
Organisms: Escherichia coli
Geographic Location: Japan|Fiji|Europe|China|USA|Germany|France|Denmark|Canada|Madagascar|Kazakhstan|Mongolia|Ethiopia|Peru|Sweden|Italy|Korea|UK|Austria|Hungary
Papers: 1
Databases: Reslit

Papers1

Expanding the beta-lactamase Family in the Human Microbiome.

PMID 39447121 · 2024

The study identifies nine novel beta-lactamases from eight distinct clusters, demonstrating their ability to confer resistance to various β-lactam antibiotics. These enzymes were experimentally validated through expression in E. coli and MIC testing.

Gene Information

Gene Name: blaa1
Allele: blaA1
Encodes: beta-lactamase
Source Database: Reslit
Confers Resistance To: penicillinoxacillinampicillinamoxicillincephalosporinsceftriaxonecefepimemeropenemaztreonam
Organisms Tested In: • Escherichia coli
Geographic Location: Japan|Fiji|Europe|China|USA|Germany|France|Denmark|Canada|Madagascar|Kazakhstan|Mongolia|Ethiopia|Peru|Sweden|Italy|Korea|UK|Austria|Hungary
Validation Method: expression in E. coli and MIC testing

Comments (0)

No comments yet. Be the first to comment!

blaa1

Gene Information

Browse AMR Genes

blaa1

Gene Information