blacmy−59

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Beta-lactamase

NCBI Pathogen Isolates

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NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to blacmy−59

AMR Rules

Browse AMR rules for blacmy−59

Validation StatusCandidate

Overview

Mechanism: Hydrolyzes beta-lactam antibiotics
Validation Method: Whole-genome sequencing and enzymatic activity assay
Drug Classes: ampicillin
Organisms: Escherichia coli
Geographic Location: Canada
Papers: 1
Databases: Reslit

Papers1

Prevalence and mechanisms of antibiotic resistance in Escherichia coli isolated from mastitic dairy cattle in Canada.

PMID 34332549 · 2021

The study identified several AMR genes in E. coli isolates from bovine mastitis, including beta-lactamases (blaTEM-1, blaCARB-3, blaCMY-59), tetracycline resistance genes (tetA, tetB, tetC), aminoglycoside resistance genes (aph(3')-Ia, aph(3'')-Ib, aph(6)-Id, aadA2), and multidrug efflux pump genes (acrA, acrB, acrD, tolC, baeR, emrA, emrB).

Gene Information

Gene Name: blacmy−59
Allele: blaCMY−59
Encodes: Beta-lactamase
Source Database: Reslit
Mechanism: Hydrolyzes beta-lactam antibiotics
Confers Resistance To: ampicillin
Organisms Tested In: • Escherichia coli
Geographic Location: Canada
Validation Method: Whole-genome sequencing and enzymatic activity assay
Sequence Accession: NCBI BioProject: PRJNA638521|PRJNA612640

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blacmy−59

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blacmy−59

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