Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
beta-lactamase
Overview
Bloodstream Infections by Extended-Spectrum β-Lactamase-Producing Escherichia coli and Klebsiella pneumoniae in Children: Epidemiology and Clinical Outcome.
The study identifies several extended-spectrum beta-lactamases (ESBLs) including TEM-52, SHV-2a, TEM-88, CMY-1-like, and CTX-M-14 in Escherichia coli and Klebsiella pneumoniae isolates from children with bloodstream infections. These ESBLs confer resistance to various beta-lactam antibiotics.
Modified CLSI extended-spectrum beta-lactamase (ESBL) confirmatory test for phenotypic detection of ESBLs among Enterobacteriaceae producing various beta-lactamases.
The study evaluated a modified CLSI ESBL confirmatory test for the phenotypic detection of extended-spectrum beta-lactamases (ESBLs) among Enterobacteriaceae producing various beta-lactamases, including KPC, VIM, NDM, and OXA-48. The modified test significantly improved the sensitivity and specificity of ESBL detection compared to the standard CLSI test.
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