Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
extended-spectrum beta-lactamase
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| blaCTX−M−14 | Reslit | 3 | ceftazidime, cefotaxime +4 | Klebsiella pneumoniae +2 | Shanghai, China, South Korea, Thailand | 2021, 2022, 2025 | - | - |
| blactx−M−14 | Reslit | 1 | cefotaxime | Escherichia coli | - | 2025 | - | - |
Drug Susceptibility and Molecular Epidemiology of Klebsiella pneumoniae Bloodstream Infection in ICU Patients in Shanghai, China.
The study identified bla CTX-M-14, bla CTX-M-15, bla CTX-M-55, and bla KPC-2 as the most prevalent resistance genes in K. pneumoniae isolates from ICU patients in Shanghai, China.
Genetic characterization of third- or fourth-generation cephalosporin-resistant avian pathogenic Escherichia coli isolated from broilers.
The study identified various beta-lactamase genes, including bla CTX-M-15, bla TEM-1, bla CTX-M-1, bla CTX-M-14, bla SHV-12, bla CTX-M-27, bla OXA-1, bla TEM-135, and bla CMY-2, in third- or fourth-generation cephalosporin-resistant avian pathogenic E. coli isolates from Korean broiler operations.
Harnessing CRISPR interference to resensitize laboratory strains and clinical isolates to last resort antibiotics.
The study demonstrates that CRISPR interference (CRISPRi) can re-sensitize laboratory strains and clinical isolates to last-resort antibiotics by repressing the expression of specific antibiotic resistance genes (ARGs).
Genetic insights into antimicrobial resistance and virulence characteristics of Salmonella enterica isolated from Nile tilapia sourced from retail markets in Thailand.
The study identified multiple antimicrobial resistance (AMR) genes in Salmonella enterica isolates from Nile tilapia, including beta-lactamases (bla TEM−1B, bla CTX−M−55, bla CTX−M−14, bla LAP−2), quinolone resistance genes (qnrS1, qnrS13), tetracycline resistance genes (tet(A), tet(B), tet(M)), aminoglycoside resistance genes (aadA2, aph(3’’)-Ib, aph(6)-Id, aac(6’)-Ia), sulfonamide resistance genes (sul1, sul2, sul3), florfenicol resistance gene (floR), and efflux pump systems (mdsABC, mdtK).
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