blactx−m−9 group

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beta-lactamase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to blactx−m−9 group

AMR Rules

Browse AMR rules for blactx−m−9 group

Validation StatusCandidate

Overview

Validation Method: PCR and sequencing
Drug Classes: carbapenems, ampicillin, ceftazidime, ceftriaxone
Organisms: Salmonella enterica subsp. enterica, Klebsiella pneumoniae
Geographic Location: China, Saudi Arabia
Papers: 2
Databases: Reslit

Papers2

S. Enteritidis and S. Typhimurium Harboring SPI-1 and SPI-2 Are the Predominant Serotypes Associated With Human Salmonellosis in Saudi Arabia.

PMID 31214517 · 2019

The study identified the presence of bla TEM−1, bla OXA−1, bla CTX−M−1 group, bla CTX−M−9 group, and bla OXA−48 genes in Salmonella isolates, which confer resistance to various antibiotics. Additionally, mutations in gyrA and parC genes were associated with ciprofloxacin resistance.

Gene Information

Gene Name: blactx−m−9 group
Allele: blaCTX−M−9 group
Encodes: beta-lactamase
Source Database: Reslit
Confers Resistance To: carbapenems
Organisms Tested In: • Salmonella enterica subsp. enterica
Geographic Location: Saudi Arabia
Validation Method: PCR and sequencing

An Outbreak of Carbapenem-Resistant and Hypervirulent Klebsiella pneumoniae in an Intensive Care Unit of a Major Teaching Hospital in Wenzhou, China.

PMID 31552210 · 2019

The study identified carbapenem-resistant and hypervirulent Klebsiella pneumoniae isolates carrying bla KPC−2, aac(3')-Ia, aac(6')-Ib, ANT(3')-Ia, rmtB, rmtC, qnrB, qnrS, oqxA, bla SHV−11, bla CTX−M−2 group, bla CTX−M−9 group, bla TEM−1, bla CMY−2, and bla DHA genes, contributing to multidrug resistance.