bladha1

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beta-lactamase

NCBI Pathogen Isolates

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NCBI Reference Gene Catalog

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UniProt

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AMR Rules

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Validation StatusCandidate

Overview

Validation Method: PCR and sequencing
Drug Classes: ampicillin, piperacillin
Organisms: Klebsiella pneumoniae
Geographic Location: Kenya
Papers: 1
Databases: Reslit

Papers1

Antimicrobial Resistance and Virulence Characteristics of Klebsiella pneumoniae Isolates in Kenya by Whole-Genome Sequencing.

PMID 35631066 · 2022

The study identified several AMR genes in K. pneumoniae isolates from Kenya, including blaCTX-M-15, blaTEM-181, blaOXA-181, blaNDM-1, mcr-8, armA, rmtF, aac(6')-Ib-cr, aph(3")-ib, aph(6)-id, dfrA, sul2, qnrB, tetA, and catII, which confer resistance to various antibiotics such as beta-lactams, carbapenems, aminoglycosides, fluoroquinolones, tetracyclines, and chloramphenicol.

Gene Information

Gene Name: bladha1
Allele: blaDHA1
Encodes: beta-lactamase
Source Database: Reslit
Confers Resistance To: ampicillinpiperacillin
Organisms Tested In: • Klebsiella pneumoniae
Geographic Location: Kenya
Validation Method: PCR and sequencing
Sequence Accession: NCBI GenBank: PRJNA777842

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bladha1

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bladha1

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