Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
beta-lactamase
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| blaOXA-1-like | Reslit | 3 | ampicillin, ampicillin sulbactam +4 | Klebsiella pneumoniae +1 | Brazil, North Sea|Baltic Sea, United States | 2022, 2023 | MT330306|MT330308|MT330310|MT330312|MT330313|MT330314|MT330316|MT330317|MT330319|MT330320|MT330322|MT330324 | - |
| blaOXA-1-Like | Reslit | 1 | ceftazidime, cefepime +3 | Pseudomonas aeruginosa | Guangdong, China | 2023 | - | - |
Multidrug-resistant Klebsiella pneumoniae: a retrospective study in Manaus, Brazil.
The study identified multiple multidrug-resistant (MDR) and extensively drug-resistant (XDR) Klebsiella pneumoniae strains in Manaus, Brazil, harboring various beta-lactamase genes such as bla OXA-1-like, bla CTX-M-Gp1, and bla KPC. These strains exhibited resistance to multiple antibiotic classes, including carbapenems, cephalosporins, and penicillins.
Occurrence of Antimicrobial-Resistant Escherichia coli in Marine Mammals of the North and Baltic Seas: Sentinels for Human Health.
The study identified antimicrobial-resistant Escherichia coli in marine mammals from the North and Baltic Seas, highlighting the presence of resistance genes such as blaTEM, strA, strB, aadA1, sul1, sul2, tet(A), tet(B), tet(D), qnrS, floR, catA1, blaOXA-1-like, blaSHV, and blaCMY-2.
Trends of β-Lactamase Occurrence Among Escherichia coli and Klebsiella pneumoniae in United States Hospitals During a 5-Year Period and Activity of Antimicrobial Agents Against Isolates Stratified by β-Lactamase Type.
The study identified various β-lactamase genes, including bla CTX-M-15, bla CTX-M-55, bla CTX-M-14, bla CTX-M-27, bla SHV-12, bla SHV-7, bla SHV-27, bla TEM-1, bla TEM-12, bla CMY-2, bla DHA-1, bla FOX-5, bla OXA-1, bla OXA-1-like, bla KPC-2, bla KPC-3, bla NDM-1, bla NDM-5, bla OXA-181, bla OXA-48, and bla OXA-232, which confer resistance to β-lactam antibiotics. The study also found that CTX-M-15 was the most prevalent β-lactamase gene, and there was a notable increase in ESBL-producing isolates among K. pneumoniae.
Whole-genome sequencing reveals high-risk clones of Pseudomonas aeruginosa in Guangdong, China.
The study identified multiple AMR genes, including aac(6')-IIa, aac(6')-Ib4, aac(6')-Ib7, aac(6')-Ib9, aac(6')-Ib10, aac(3)-IId, aadA, aadA2, aadA3, aadA7, aadA13, bla OXA-50-Like, bla OXA-1-Like, bla OXA-10-Like, bla OXA-21-Like, bla VIM-2, bla IMP-9, bla IMP-45, bla KPC-2, bla CTX-M-13, bla CARB-1, bla CARB-3, qnrVC1, qnrVC6, bla PDC-3, and bla PDC-5, in Pseudomonas aeruginosa isolates from Guangdong, China, highlighting the high prevalence of multidrug-resistant and carbapenem-resistant strains.
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