blaoxa-55 -like

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beta-lactamase

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Protein entries specific to blaoxa-55 -like

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Validation StatusCandidate

Overview

Mechanism: carbapenem resistance
Validation Method: CRISPR/Cas9-mediated gene knockout and MIC testing
Drug Classes: imipenem
Organisms: Shewanella algae
Papers: 1
Databases: Reslit

Papers1

Reversal of carbapenem-resistance in Shewanella algae by CRISPR/Cas9 genome editing.

PMID 30809393 · 2019

The study identifies the bla OXA-55 -like gene as essential for carbapenem resistance in Shewanella algae and demonstrates that its knockout restores susceptibility to imipenem using CRISPR/Cas9 genome editing.

Gene Information

Gene Name: blaoxa-55 -like
Allele: blaOXA-55 -like
Encodes: beta-lactamase
Source Database: Reslit
Mechanism: carbapenem resistance
Confers Resistance To: imipenem
Organisms Tested In: • Shewanella algae
Validation Method: CRISPR/Cas9-mediated gene knockout and MIC testing
Sequence Accession: CP032414|CP032415

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blaoxa-55 -like

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blaoxa-55 -like

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