Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
extended spectrum beta-lactamase
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| blaOXA10 | Reslit | 2 | beta lactams, ceftazidime avibactam | Vibrio fluvialis BD146 +1 | India, Iran | 2018, 2020 | EU574928|KT182072 | - |
| blaOxa10 | Reslit | 1 | beta lactams | Pseudomonas aeruginosa | Spain|Europe | 2021 | NCBI:CP053422|PRJNA667268 | - |
A Highly Promiscuous Integron, Plasmids, Extended Spectrum Beta Lactamases and Efflux Pumps as Factors Governing Multidrug Resistance in a Highly Drug Resistant Vibrio fluvialis Isolate BD146 from Kolkata, India.
The study identified several AMR genes and mutations contributing to multidrug resistance in Vibrio fluvialis BD146, including blaOXA10, arr3, aadA1, cmlA, dfrVI, qnrVC5, and BDint, as well as mutations in gyrA and parC.
First Study of Antimicrobial Activity of Ceftazidime-Avibactam and Ceftolozane-Tazobactam Against Pseudomonas aeruginosa Isolated from Patients with Urinary Tract Infection in Tehran, Iran.
The study identified several beta-lactamase and carbapenemase genes, including bla OXA10, bla VIM, bla OXA48, bla OXA2, bla CTX-M, bla PER, and bla NDM, which contribute to resistance against ceftazidime-avibactam and ceftolozane-tazobactam in Pseudomonas aeruginosa isolates from Iran.
Rapid evolution and host immunity drive the rise and fall of carbapenem resistance during an acute Pseudomonas aeruginosa infection.
The study identifies mutations in oprD, wbpM, and mexAB-OprM that contribute to carbapenem and β-lactam resistance in Pseudomonas aeruginosa during an acute infection. Additionally, plasmid-borne resistance genes such as bla-Oxa10, aacA4, and sul1 were found to play a role in antibiotic resistance.
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