Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
beta-lactamase
Overview
A high prevalence of multi-drug resistant Gram-negative bacilli in a Nepali tertiary care hospital and associated widespread distribution of Extended-Spectrum Beta-Lactamase (ESBL) and carbapenemase-encoding genes.
The study identified a high prevalence of multi-drug resistant Gram-negative bacilli carrying ESBL and carbapenemase genes, including bla TEM, bla CTXM-1, bla CTXM-8, bla OXA, bla OXA51, bla OXA23, bla NDM-1, and bla KPC.
Antimicrobial resistance genes harbored in invasive Acinetobacter calcoaceticus-baumannii complex isolated from Korean children during the pre-COVID-19 pandemic periods, 2015-2020.
The study identified blaOXA23 as the primary carbapenem resistance gene in Acinetobacter baumannii (AB) isolates, along with blaADC, blaOXA51, and various aminoglycoside resistance genes such as aad and armA. Fluoroquinolone resistance was linked to mutations in gyrA and parC. Efflux pumps abe and ade were widespread in AB isolates.
Carbapenem resistance in gram-negative pathogens in an Iranian hospital: high prevalence of OXA-type carbapenemase genes.
The study identified a high prevalence of OXA-type carbapenemase genes, particularly bla OXA48, bla OXA143, and bla OXA58, among carbapenem-resistant gram-negative bacteria in an Iranian hospital.
Development and clinical application of a PCR-UV assay for detection of carbapenem resistant Acinetobacter baumannii in bloodstream infections.
The study developed a PCR-UV assay for rapid detection of carbapenem-resistant Acinetobacter baumannii (CRAB) by targeting the blaOXA23 and blaOXA51 genes, which encode carbapenemases responsible for carbapenem resistance.
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