blaoxy-2-35

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class A beta-lactamase

NCBI Pathogen Isolates

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UniProt

Protein entries specific to blaoxy-2-35

AMR Rules

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Validation StatusCandidate

Overview

Validation Method: genome sequencing and in vitro antimicrobial susceptibility testing
Drug Classes: penicillin
Organisms: Klebsiella oxytoca
Geographic Location: New Hampshire, USA|global
Papers: 1
Databases: Reslit

Papers1

Phylogenetic lineages and antimicrobial resistance determinants of clinical Klebsiella oxytoca spanning local to global scales.

PMID 37676032 · 2023

The study identified 10 variants of the intrinsic beta-lactamase gene blaOXY-2 in clinical Klebsiella oxytoca isolates, which confer resistance to penicillins. Additionally, two novel blaOXY-2 variants (blaOXY-2-35 and blaOXY-2-36) were discovered.

Gene Information

Gene Name: blaoxy-2-35
Allele: blaOXY-2-35
Encodes: class A beta-lactamase
Source Database: Reslit
Confers Resistance To: penicillin
Organisms Tested In: • Klebsiella oxytoca
Geographic Location: New Hampshire, USA|global
Validation Method: genome sequencing and in vitro antimicrobial susceptibility testing
Sequence Accession: NZ_OW967518.1|NZ_CP070144.1|NZ_CP011618.1

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blaoxy-2-35

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blaoxy-2-35

Gene Information