Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
serine beta-lactamase
Overview
In vitro potency of xeruborbactam in combination with multiple β-lactam antibiotics in comparison with other β-lactam/β-lactamase inhibitor (BLI) combinations against carbapenem-resistant and extended-spectrum β-lactamase-producing Enterobacterales.
Xeruborbactam (XER) showed superior in vitro potency against carbapenem-resistant and extended-spectrum β-lactamase-producing Enterobacterales when combined with various β-lactam antibiotics compared to other β-lactam/β-lactamase inhibitor combinations. XER effectively inhibited a wide range of β-lactamases, including metallo-β-lactamases (MBLs) and serine β-lactamases, enhancing the activity of antibiotics such as meropenem, cefepime, ceftolozane, ceftriaxone, aztreonam, piperacillin, and ertapenem.
Unveiling the microevolution of antimicrobial resistance in selected Pseudomonas aeruginosa isolates from Egyptian healthcare settings: A genomic approach.
The study identified multiple antimicrobial resistance genes and mutations in Pseudomonas aeruginosa isolates from Egyptian healthcare settings, highlighting extensive drug resistance and the role of mobile genetic elements in the spread of resistance.
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