Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
beta-lactamase
Overview
Comparison of the inoculum effect of in vitro antibacterial activity of Imipenem/relebactam and Ceftazidime/avibactam against ESBL-, KPC- and AmpC-producing Escherichia coli and Klebsiella pneumoniae.
The study evaluated the inoculum effect of Imipenem/relebactam (IMR) and Ceftazidime/avibactam (CZA) against ESBL-, KPC-, and AmpC-producing E. coli and K. pneumoniae. It identified several beta-lactamase genes, including bla TEM-1, bla AmpC, bla CTX-M-14, bla OXA-10, bla CTX-M-55, bla CMY-42, bla CTX-M-15, bla KPC-2, bla OXA-9, bla SHV-182, bla SHV-18, bla OXA-2, bla OKP-B-7, bla DHA-1, bla SHV-27, bla CTX-M-65, bla SHV-11, bla SHV-145, bla SHV-12, bla SHV-106, bla SHV-110, bla SHV106, and bla CTX-M-14, which confer resistance to ceftazidime and/or imipenem.
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