Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
beta-lactamase
Overview
Occurrence and temporal distribution of extended-spectrum beta-lactamase-producing Escherichia coli in clams from the Central Adriatic, Italy.
The study identified several beta-lactamase genes, including bla CTX-M-1, bla CTX-M-14, bla CTX-M-15, bla CTX-M-27, bla CTX-M-55, bla SHV12, bla CMY-2, bla TEM-1B, bla TEM-106, and bla TEM-126, which confer resistance to various β-lactam antibiotics. Other resistance genes such as aac(6′)-Ib-cr, qnrS1, tet(A), tet(B), tet(M), aadA5, aadA2b, sul1, sul2, sul3, dfrA17, dfrA5, dfrA14, dfrA12, mph(A), cmlA1, catA2, aac(3)-IIa, aac(3)-IId, and lnu(F) were also characterized, providing insights into the multidrug resistance profiles of ESBL-producing E. coli isolates from clams in the Central Adriatic.
Costs of antibiotic resistance genes depend on host strain and environment and can influence community composition.
The study identifies that certain antibiotic resistance genes (ARGs) such as bla TEM-116 *, cat, and dfrA5 impose fitness costs in various Escherichia spp. strains, highlighting the variability of these effects across different host backgrounds.
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