blatem-1-a

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beta-lactamase

NCBI Pathogen Isolates

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NCBI Reference Gene Catalog

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UniProt

Protein entries specific to blatem-1-a

AMR Rules

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Validation StatusCandidate

Overview

Mechanism: beta-lactamase-mediated hydrolysis
Validation Method: PCR and sequencing
Drug Classes: cefoxitin, cefotaxime, ceftazidime, ampicillin, ticarcillin
Organisms: Escherichia coli, Klebsiella pneumonia, Citrobacter freundii, Shigella boydii
Geographic Location: Tunisia
Papers: 1
Databases: Reslit

Papers1

Detection of Extended-Spectrum β-Lactamases (ESBL) Producing Enterobacteriaceae from Fish Trapped in the Lagoon Area of Bizerte, Tunisia.

PMID 32596358 · 2020

The study identified several β-lactamase genes (bla CTX-M-1, bla CTX-M-15, bla CTX-M-9, bla OXA-1, and bla TEM-1-a) and other resistance genes (sul1, sul2, tetA, aac(6')-Ib-cr, qnrA, and qnrB) in ESBL-producing Enterobacteriaceae isolated from fish in the Bizerte lagoon, highlighting the presence of multidrug-resistant bacteria in aquatic environments.

Gene Information

Gene Name: blatem-1-a
Allele: blaTEM-1-a
Encodes: beta-lactamase
Source Database: Reslit
Mechanism: beta-lactamase-mediated hydrolysis
Confers Resistance To: cefoxitincefotaximeceftazidimeampicillinticarcillin
Organisms Tested In: • Escherichia coli
• Klebsiella pneumonia
• Citrobacter freundii
• Shigella boydii
Geographic Location: Tunisia
Validation Method: PCR and sequencing

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blatem-1-a

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blatem-1-a

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