Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
beta-lactamase
Overview
Diversity and distribution of commensal fecal Escherichia coli bacteria in beef cattle administered selected subtherapeutic antimicrobials in a feedlot setting.
The study identified bla TEM1, tet (A), and sul2 as prevalent resistance genes in commensal E. coli from beef cattle, highlighting the impact of antimicrobial use on resistance dissemination.
Longitudinal characterization of resistant Escherichia coli in fecal deposits from cattle fed subtherapeutic levels of antimicrobials.
The study identified several AMR genes, including blaTEM1, tetA, tetB, tetC, sul1, and sul2, in Escherichia coli from cattle fecal deposits. These genes conferred resistance to ampicillin, tetracycline, and sulfonamides.
Characteristics of plasmids in multi-drug-resistant Enterobacteriaceae isolated during prospective surveillance of a newly opened hospital in Iraq.
The study identified various plasmid-borne antimicrobial resistance genes in multi-drug-resistant Enterobacteriaceae isolates from a newly opened hospital in Iraq, including aminoglycoside, beta-lactam, sulfamethoxazole/trime-thoprim, tetracycline, and chloramphenicol resistance genes.
Comparative genomic analysis and virulence differences in closely related salmonella enterica serotype heidelberg isolates from humans, retail meats, and animals.
The study identified several AMR genes and mutations in Salmonella enterica serotype Heidelberg isolates, including bla, aac(6')-Ib, tet(M), qnrS1, and erm(B). Mutations in genes such as SEEHRA37_03221, SEEHRA37_24108, and others were associated with resistance traits.
Public health surveillance in the UK revolutionises our understanding of the invasive Salmonella Typhimurium epidemic in Africa.
The study identified the presence of the blaCTX-M-15 gene in a UK-isolated lineage 2 strain of Salmonella Typhimurium, highlighting the potential for spread of extended-spectrum beta-lactamase resistance.
Comparison of antimicrobial resistance genes in feedlots and urban wastewater.
The study identified various antimicrobial resistance genes in feedlots and urban wastewater, highlighting the prevalence of sulfonamide, tetracycline, macrolide, fluoroquinolone, and β-lactam resistance genes in different environments.
Clonal relationships, antimicrobial susceptibilities, and molecular characterization of extended-spectrum beta-lactamase-producing Escherichia coli isolates from urinary tract infections and fecal samples in Southeast Iran.
The study identified bla CTX-Mgroup1, bla TEM1, and bla OXA1 as the primary extended-spectrum beta-lactamase genes in E. coli isolates from urinary tract infections and fecal samples in Southeast Iran, highlighting their role in multidrug resistance.
The kinetics of TEM1 antibiotic degrading enzymes that are displayed on Ure2 protein nanofibrils in a flow reactor.
The study characterizes the TEM1 beta-lactamase, demonstrating its ability to hydrolyze ampicillin when displayed on Ure2 protein nanofibrils, maintaining 80% of the catalytic turnover rate compared to the soluble enzyme.
An African Salmonella Typhimurium ST313 sublineage with extensive drug-resistance and signatures of host adaptation.
The study identifies an extensively drug-resistant (XDR) sublineage II.1 of Salmonella Typhimurium ST313 in the Democratic Republic of the Congo, carrying resistance genes such as catA, blaTEM1, dfrA, blaSHV-2A, mphA, qnrS, and gyrA mutations, along with an IncHI2 plasmid pSTm-ST313-II.1.
Genetically Engineered Yeast for Enhanced Biodegradation of Β-lactam Antibiotics.
The study demonstrates the successful engineering of Saccharomyces cerevisiae to secrete beta-lactamase (TEM1) upon induction by α-factor, enabling the degradation of various β-lactam antibiotics including ampicillin, amoxicillin, cloxacillin, penicillin G, cefalotin, and piperacillin.
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