blatem1β

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beta-lactamase

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UniProt

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Validation StatusCandidate

Overview

Mechanism: hydrolyzes beta-lactam antibiotics
Validation Method: whole-genome sequencing and phenotypic testing
Drug Classes: ampicillin
Organisms: Salmonella enterica serovar Pullorum
Geographic Location: China
Papers: 1
Databases: Reslit

Papers1

Genome-Based Analysis of Genetic Diversity, Antimicrobial Susceptibility, and Virulence Gene Distribution in Salmonella Pullorum Isolates from Poultry in China.

PMID 39335264 · 2024

The study identified several AMR genes and mutations in Salmonella Pullorum isolates from China, including aac(6')-Iaa, aadA5, blaTEM1β, sul2, tet(A), and qacE, as well as gyrA mutations (S83F, S84F, D87N), which are associated with resistance to streptomycin, ampicillin, ciprofloxacin, sulfamethoxazole, tetracycline, and disinfectants.

Gene Information

Gene Name: blatem1β
Allele: blaTEM1β
Encodes: beta-lactamase
Source Database: Reslit
Mechanism: hydrolyzes beta-lactam antibiotics
Confers Resistance To: ampicillin
Organisms Tested In: • Salmonella enterica serovar Pullorum
Geographic Location: China
Validation Method: whole-genome sequencing and phenotypic testing
Sequence Accession: PRJNA1138287

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blatem1β

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blatem1β

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