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cdr20291_1187

envelope stress response regulator

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to cdr20291_1187

Browse AMR rules for cdr20291_1187

Overview

Drug Classes: daptomycin
Organisms: Clostridioides difficile
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
R49I	-	-	Clostridioides difficile	daptomycin	Reslit	Candidate

Papers1

1

Identification of Clostridioides difficile mutants with increased daptomycin resistance.

PMID 38376203 · 2024

Mutation Information

cdr20291_1187: p.R49I

Protein Change: R49I
Organisms: Clostridioides difficile
Confers Resistance To: daptomycin
Validation Method: whole-genome sequencing and functional validation
Source Database: Reslit