cfac

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cyclopropane-fatty-acyl-phospholipid synthase

NCBI Pathogen Isolates

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NCBI Reference Gene Catalog

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UniProt

Protein entries specific to cfac

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Validation StatusCandidate

Overview

Mechanism: Increased expression of cfa gene is associated with ampicillin tolerance
Validation Method: RT-PCR showing 7.56-fold higher expression in tolerant strain
Drug Classes: ampicillin
Organisms: Shigella
Papers: 1
Databases: Reslit

Papers1

The role of cfa gene in ampicillin tolerance in Shigella.

PMID 31686867 · 2019

The study identifies the cfa gene as being associated with ampicillin tolerance in Shigella, with increased expression observed in the tolerant strain.

Gene Information

Gene Name: cfac
Allele: cfa
Encodes: cyclopropane-fatty-acyl-phospholipid synthase
Source Database: Reslit
Mechanism: Increased expression of cfa gene is associated with ampicillin tolerance
Confers Resistance To: ampicillin
Organisms Tested In: • Shigella
Validation Method: RT-PCR showing 7.56-fold higher expression in tolerant strain

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cfac

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cfac

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