Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
Cfr 23S ribosomal RNA methyltransferase
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| cfrE | Card DatabaseReslit | 2 | linezolid | Clostridium sp. AF37-7 +1 | Mexico | 2021 | QUDP01000003.1 | RHO92765.1 |
| Cfr(E) | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 6 | phenicols, lincosamides +16 | Clostridium difficile +2 | Latin America, USA|United Kingdom|Mexico|China | 2019, 2025 | KM359438|CCL89685|AJ879565|MG707078|CAADRH000000000|CAADRI000000000|ERR467555 | RHO92765.1 |
cfr(B), cfr(C), and a New cfr-Like Gene, cfr(E), in Clostridium difficile Strains Recovered across Latin America.
The study identifies cfr(B), cfr(C), and a new cfr-like gene, cfr(E), in Clostridium difficile strains from Latin America, demonstrating their ability to confer resistance to multiple antibiotics through hypermethylation of 23S rRNA.
cfr(B), cfr(C), and a New cfr-Like Gene, cfr(E), in Clostridium difficile Strains Recovered across Latin America.
cfr(B), cfr(C), and a New cfr-Like Gene, cfr(E), in Clostridium difficile Strains Recovered across Latin America.
cfr(B), cfr(C), and a New cfr-Like Gene, cfr(E), in Clostridium difficile Strains Recovered across Latin America.
Molecular Epidemiology and Antimicrobial Resistance of Clostridioides difficile in Hospitalized Patients From Mexico.
The study identified several AMR genes and mutations in C. difficile isolates from Mexico, including cfrE, ermB, aadE, aadA27, aac(6')-Ie-aph(2'')-Ia, catP, blaCDD2, blaCCD1, tetM, tetO, tetB, tetA, and cdeA, along with mutations in rpoB, rpoC, fusA, and pbp2 associated with resistance to various antibiotics.
Genomic Characterization of Linezolid-Resistant Clostridioides difficile Harboring cfr Variants.
The study identifies cfr gene variants (cfr(B), cfr(C), and cfr(E)) in linezolid-resistant Clostridioides difficile strains, highlighting their association with resistance and the presence of specific mutations in these genes.
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