Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
CfxA beta-lactamase
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| CfxA2 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 13 | BETA-LACTAM, UNKNOWN BETA-LACTAM +4 | Prevotella intermedia +15 | South Africa, Denmark, North America|Eastern Europe, Norway, Michigan|United States, Bangladesh | 2003, 2006, 2015, 2016, 2019, 2020, 2023, 2025 | AF118110.1 | AAD23513.1 |
| cfxA2 | ResFinder Database | 1 | UNKNOWN BETA-LACTAM | Prevotella denticola | - | 2003 | AF504914 | - |
Sequence analysis of cfxA2-like beta-lactamases in Prevotella species.
Sequence analysis of cfxA2-like beta-lactamases in Prevotella species.
Sequence analysis of cfxA2-like beta-lactamases in Prevotella species.
Sequence analysis of cfxA2-like beta-lactamases in Prevotella species.
Detection of cfxA and cfxA2, the beta-lactamase genes of Prevotella spp., in clinical samples from dentoalveolar infection by real-time PCR.
The study identifies cfxA and cfxA2 as beta-lactamase genes responsible for penicillin resistance in Prevotella spp. isolates from dentoalveolar infections, demonstrating their prevalence and utility in molecular detection.
Metagenomic Analysis of Antibiotic Resistance Genes in Dairy Cow Feces following Therapeutic Administration of Third Generation Cephalosporin.
Ceftiofur treatment led to an increase in β-lactam resistance genes, including CfxA2 and CfxA3, in dairy cow feces, indicating a rapid and measurable impact on the fecal metagenome.
Detection of cfxA2, cfxA3, and cfxA6 genes in beta-lactamase producing oral anaerobes.
The study identified cfxA2, cfxA3, and cfxA6 genes in beta-lactamase-producing oral anaerobes, with 76.7%, 14%, and 9.3% of isolates carrying these genes, respectively. These genes conferred resistance to penicillin and amoxicillin.
Complete hybrid genome assembly of clinical multidrug-resistant Bacteroides fragilis isolates enables comprehensive identification of antimicrobial-resistance genes and plasmids.
The study identifies multiple antimicrobial resistance genes in multidrug-resistant Bacteroides fragilis isolates, including cfiA, nim, erm, tet, and others, using hybrid genome assembly and ABRicate screening.
Ribaxamase, an Orally Administered beta-lactamase, Diminishes Changes to Acquired Antimicrobial Resistance of the Gut Resistome in Patients Treated with Ceftriaxone.
The study identified several beta-lactamase and vancomycin resistance genes that were significantly increased in placebo-treated patients compared to ribaxamase-treated patients following ceftriaxone exposure.
Differential response to prolonged amoxicillin treatment: long-term resilience of the microbiome versus long-lasting perturbations in the gut resistome.
The study found that prolonged amoxicillin treatment leads to an increase in the abundance and diversity of antimicrobial resistance genes (ARGs) in the gut microbiome, particularly beta-lactamase genes such as cfxA and its variants, as well as tetracycline and macrolide resistance genes.
Persistent effects of intramammary ceftiofur treatment on the gut microbiome and antibiotic resistance in dairy cattle.
The study identified the persistence of extended-spectrum beta-lactamase (ESBL) genes, including blaCTX-M, blaCMY, and blaCfxA, in the gut microbiome of dairy cattle following intramammary ceftiofur treatment. These genes were associated with increased resistance to ceftiofur and were observed to persist for up to 9 weeks post-treatment.
Potential pathogens and antimicrobial resistance genes in household environments: a study of soil floors and cow dung in rural Bangladesh.
The study identified multiple antimicrobial resistance genes (ARGs) in soil floors and cow dung samples from rural Bangladesh, including sul1, tet(Q), ermF, mexF, and cfxA2, which confer resistance to sulfonamides, tetracycline, macrolides, lincosamides, streptogramins, and cephalosporins.
Dietary impact on the gut resistome: western diet independently increases the prevalence of antibiotic resistance genes within the gut microbiota.
The study shows that a western diet independently increases the prevalence of antibiotic resistance genes (ARGs) in the gut microbiota without antibiotic exposure. Specifically, ARGs such as ErmG, CfxA2, tetQ, lnuC, and mefA were found to be significantly enriched in the gut microbiota of mice fed a western diet.
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