Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
broad-spectrum class A beta-lactamase CfxA6
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| CfxA6 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 11 | BETA-LACTAM, UNKNOWN BETA-LACTAM +6 | Prevotella sp. TF12-30 +9 | South Africa, North America|Eastern Europe, Norway, Europe, Michigan|United States | 2009, 2016, 2020, 2023, 2024, 2025 | QSQJ01000062.1 | RGK23334.1 |
| cfxA6 | ResFinder Database | 1 | UNKNOWN BETA-LACTAM | uncultured organism | - | 2009 | GQ342996 | - |
Functional characterization of the antibiotic resistance reservoir in the human microflora.
Functional characterization of the antibiotic resistance reservoir in the human microflora.
Functional characterization of the antibiotic resistance reservoir in the human microflora.
Functional characterization of the antibiotic resistance reservoir in the human microflora.
Detection of cfxA2, cfxA3, and cfxA6 genes in beta-lactamase producing oral anaerobes.
The study identified cfxA2, cfxA3, and cfxA6 genes in beta-lactamase-producing oral anaerobes, with 76.7%, 14%, and 9.3% of isolates carrying these genes, respectively. These genes conferred resistance to penicillin and amoxicillin.
Effects of Low-Dose Antibiotics on Gut Immunity and Antibiotic Resistomes in Weaned Piglets.
The study identified two transferrable ARGs, Erm(T) and tcr3, which conferred resistance to macrolide and tetracycline, respectively, in weaned piglets exposed to low-dose antibiotics.
Ribaxamase, an Orally Administered beta-lactamase, Diminishes Changes to Acquired Antimicrobial Resistance of the Gut Resistome in Patients Treated with Ceftriaxone.
The study identified several beta-lactamase and vancomycin resistance genes that were significantly increased in placebo-treated patients compared to ribaxamase-treated patients following ceftriaxone exposure.
Differential response to prolonged amoxicillin treatment: long-term resilience of the microbiome versus long-lasting perturbations in the gut resistome.
The study found that prolonged amoxicillin treatment leads to an increase in the abundance and diversity of antimicrobial resistance genes (ARGs) in the gut microbiome, particularly beta-lactamase genes such as cfxA and its variants, as well as tetracycline and macrolide resistance genes.
Longitudinal study of the short- and long-term effects of hospitalisation and oral trimethoprim-sulfadiazine administration on the equine faecal microbiome and resistome.
Oral trimethoprim-sulfadiazine (TMS) administration leads to a significant and long-lasting increase in the relative abundance of resistance genes sul2, tetQ, ant6-1a, aph(3"-lb, and lnuC in the equine faecal microbiome.
Persistent effects of intramammary ceftiofur treatment on the gut microbiome and antibiotic resistance in dairy cattle.
The study identified the persistence of extended-spectrum beta-lactamase (ESBL) genes, including blaCTX-M, blaCMY, and blaCfxA, in the gut microbiome of dairy cattle following intramammary ceftiofur treatment. These genes were associated with increased resistance to ceftiofur and were observed to persist for up to 9 weeks post-treatment.
Segatella clades adopt distinct roles within a single individual's gut.
The study identifies cfxA6 and tetQ as intrinsic antibiotic resistance genes in Segatella clades, demonstrating resistance to ampicillin and tetracycline, respectively.
Wilson's disease-associated gut dysbiosis: novel insights into microbial functional alterations, virulence changes, and resistance markers.
The study identified several antibiotic resistance genes (ARGs) associated with Wilson's disease, including tetQ, ermB, cfxA6, Bbif_ileS_MUP, and Bado_rpoB_RIF, which were found to be differentially abundant in patients compared to healthy controls.
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