Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
cardiolipin synthase
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| F60S | - | - | Staphylococcus aureus | daptomycin | Reslit | Candidate |
| A23V | - | - | Staphylococcus aureus | daptomycin | Reslit | Candidate |
| S337L | - | - | Staphylococcus aureus | daptomycin | Reslit | Candidate |
| L52F | - | - | Staphylococcus aureus | daptomycin | Reslit | Candidate |
| V135I | - | - | Staphylococcus aureus | daptomycin | Reslit | Candidate |
| H205R | - | - | Staphylococcus aureus | daptomycin | Reslit | Candidate |
| G122D | - | - | Staphylococcus capitis | daptomycin | Reslit | Candidate |
| D82Y | - | - | - | daptomycin | Reslit | Candidate |
| A280T | - | - | - | daptomycin | Reslit | Candidate |
| T33N | - | - | - | daptomycin | Reslit | Candidate |
| R295C | - | - | - | daptomycin | Reslit | Candidate |
Heterogeneity of genetic pathways toward daptomycin nonsusceptibility in Staphylococcus aureus determined by adjunctive antibiotics.
Comprehensive analysis of phospholipids and glycolipids in the opportunistic pathogen Enterococcus faecalis.
The study identifies mutations in genes related to cardiolipin synthesis and other functions that correlate with daptomycin resistance in Enterococcus faecalis.
Insights Into the Evolution of Staphylococcus aureus Daptomycin Resistance From an in vitro Bioreactor Model.
The study identifies mutations in mprF, pgsA, and cls2 genes associated with daptomycin resistance in Staphylococcus aureus N315 using a bioreactor model.
Molecular basis of cell membrane adaptation in daptomycin-resistant Enterococcus faecalis.
The study identifies cls1 and cls2 as cardiolipin synthases essential for daptomycin resistance in Enterococcus faecalis, and highlights the role of LiaY in mediating membrane remodeling associated with resistance.
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