Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
resistance-nodulation-cell division (RND) antibiotic efflux pump
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| A366T | - | Efflux | Campylobacter jejuni | ertapenem|meropenem | ResFinder Database | Candidate |
Sensitization of Campylobacter jejuni to fluoroquinolone and macrolide antibiotics by antisense inhibition of the CmeABC multidrug efflux transporter.
Antisense inhibition of the CmeABC multidrug efflux transporter in Campylobacter jejuni increased susceptibility to fluoroquinolone and macrolide antibiotics.
Genotyping and Antibiotic Resistance Traits in Campylobacter jejuni and coli From Pigs and Wild Boars in Italy.
The study identified various AMR genes and mutations in Campylobacter isolates from pigs and wild boars in Italy, highlighting high levels of resistance to tetracycline, ciprofloxacin, nalidixic acid, and erythromycin. Key findings include the detection of tet(O), cmeA, cmeB, cmeC, cmeR, OXA-61, and aph(3')-III genes, as well as the gyrA T86I mutation and 23S rRNA A2075G mutation.
Significant contribution of the CmeABC Efflux pump in high-level resistance to ciprofloxacin and tetracycline in Campylobacter jejuni and Campylobacter coli clinical isolates.
The CmeABC efflux pump significantly contributes to high-level resistance to tetracycline and ciprofloxacin in Campylobacter jejuni and Campylobacter coli clinical isolates. Additionally, the tetO gene and a point mutation in the gyrA gene contribute to resistance.
High-throughput sequencing reveals genetic determinants associated with antibiotic resistance in Campylobacter spp. from farm-to-fork.
The study identified several AMR genes and mutations associated with resistance to quinolones, tetracyclines, and macrolides in Campylobacter isolates from various sources. Key findings include the prevalence of blaOXA-61, tet(O), and mutations in gyrA and 23S rRNA genes.
Overview of Ecology and Aspects of Antibiotic Resistance in Campylobacter spp. Isolated from Free-Grazing Chicken Tissues in Rural Households.
The study identified several AMR genes and mutations in Campylobacter spp. isolated from free-grazing chickens, including blaOxA-61, tet(O), tet(A), cmeA, cmeB, cmeC, and a Thr-86-Ile mutation in gyrA, contributing to multidrug resistance.
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