Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
resistance-nodulation-cell division (RND) antibiotic efflux pump
Overview
| Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|
| P131Q | - | reduced expression of the porin mRNAs | Salmonella typhimurium | cephalothin|cefaclor | Reslit | Candidate |
| C191R | - | - | Providencia rettgeri | aminoglycosides | Reslit | Candidate |
| A4104443T | - | - | Escherichia coli | phenicols | Reslit | Candidate |
| W184R | - | - | - | amikacin | Reslit | Candidate |
| D31Y | - | - | - | amikacin | Reslit | Candidate |
| A79V | - | - | - | amikacin | Reslit | Candidate |
| P610Q | - | - | - | amikacin | Reslit | Candidate |
| A608V | - | - | - | amikacin | Reslit | Candidate |
| Y144N | - | - | - | carbapenemsampicillin|cephalosporins | Reslit | Candidate |
| Q242L | - | - | E. coli | kanamycin | Reslit | Candidate |
| F218Y | - | - | Escherichia coli | kanamycin | Reslit | Candidate |
| G130A | - | envelope stress sensor histidine kinase CpxA | Enterobacter cloacae | ceftibuten avibactam | Reference Gene Catalog | Candidate |
| P131L | - | envelope stress sensor histidine kinase CpxA | Enterobacter cloacae | ceftibuten avibactam | Reference Gene Catalog | Candidate |
| G12D | - | Escherichia coli | amikacin | Reslit | Candidate |
Role of the two component signal transduction system CpxAR in conferring cefepime and chloramphenicol resistance in Klebsiella pneumoniae NTUH-K2044.
The CpxAR two-component system contributes to resistance against cefepime and chloramphenicol in Klebsiella pneumoniae NTUH-K2044 by modulating efflux pump expression and outer membrane protein profiles.
Divergent evolution peaks under intermediate population bottlenecks during bacterial experimental evolution.
The study identifies rpoB and cpxA as major genes involved in rifampicin resistance in Pseudomonas fluorescens Pf0-1, with rpoB mutations being more prevalent under weak and strong bottlenecking, while cpxA mutations are more common under intermediate bottlenecking.
Genome sequencing and analysis of the first spontaneous Nanosilver resistant bacterium Proteus mirabilis strain SCDR1.
The study identifies several AMR genes in the Nanosilver-resistant Proteus mirabilis strain SCDR1, including those conferring resistance to tetracycline, fluoroquinolones, sulfonamides, daptomycin, rifamycin, elfamycins, chloramphenicol, and amikacin.
Effect of Environment on the Evolutionary Trajectories and Growth Characteristics of Antibiotic-Resistant Escherichia coli Mutants.
The study identifies a promoter mutation in the ampC gene leading to increased AmpC beta-lactamase production and resistance to amoxicillin-clavulanic acid in E. coli.
Role of cpxA Mutations in the Resistance to Aminoglycosides and β-Lactams in Salmonella enterica serovar Typhimurium.
cpxA mutations contribute to resistance to aminoglycosides and beta-lactams through activation of the CpxRA system.
Virulence Factors and Antimicrobial Resistance of Uropathogenic Escherichia coli EQ101 UPEC Isolated from UTI Patient in Quetta, Balochistan, Pakistan.
The study identified multiple antimicrobial resistance genes in the E. coli EQ101 isolate, including genes involved in antibiotic efflux, inactivation, and drug replacement. Key resistance genes include TolC, emrR, evgA, qacEdelta1, H-NS, cpxA, mdtM, aadA5, mphA, CTX-M-15, sul1, and dfrA14.
Genome mining of Escherichia coli WG5D from drinking water source: unraveling antibiotic resistance genes, virulence factors, and pathogenicity.
The study identifies multiple antibiotic resistance genes in E. coli WG5D, including multidrug efflux pumps and genes conferring resistance to various antibiotics such as fluoroquinolones, cephalosporins, and glycopeptides.
Transcriptomic Analyses to Unravel Cronobacter sakazakii Resistance Pathways.
The study identifies several AMR genes in Cronobacter sakazakii, including ampC, b1256, Z2647, ACIAD3023, gstA, MarB, BsmA, PhoP, ramA, b1526, b4189, SF1149, DUF2724, T1E_0241, B1243, Arnit_2199, ECP_0940, ML0773, and ampC, which are associated with resistance to various antibiotics such as penicillins, aminoglycosides, tetracyclines, fluoroquinolones, and cephalosporins.
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