degS

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periplasmic protease

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Protein entries specific to degS

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Validation StatusCandidate

Overview

Validation Method: transposon mutant sequencing (Tn-seq) and targeted Tn-seq
Drug Classes: meropenem
Organisms: Burkholderia thailandensis, Burkholderia pseudomallei
Papers: 1
Databases: Reslit

Papers1

Determinants of Extreme β-Lactam Tolerance in the Burkholderia pseudomallei Complex.

PMID 29439964 · 2018

The study identifies genes involved in meropenem tolerance in Burkholderia species, including BTH_I0069, ldcA, prc, degS, and ftsN, which contribute to tolerance under various slow-growth conditions.

Gene Information

Gene Name: degS
Allele: degS
Encodes: periplasmic protease
Source Database: Reslit
Confers Resistance To: meropenem
Organisms Tested In: • Burkholderia thailandensis
• Burkholderia pseudomallei
Validation Method: transposon mutant sequencing (Tn-seq) and targeted Tn-seq

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degS

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degS

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