dfr7

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dihydrofolate reductase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

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UniProt

Protein entries specific to dfr7

AMR Rules

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Validation StatusCandidate

Overview

Validation Method: PCR screening and DNA sequencing
Drug Classes: trimethoprim
Organisms: Avian pathogenic Escherichia coli
Geographic Location: China
Papers: 1
Databases: Reslit

Papers1

Effects of in ovo probiotic administration on the incidence of avian pathogenic Escherichia coli in broilers and an evaluation on its virulence and antimicrobial resistance properties.

PMID 33518345 · 2021

The study identified various antimicrobial resistance genes in APEC isolates, including blaTEM, aac(3)-VIa, aac(3)-VIb, aadA, tetA, tetB, dfr7, qacEΔ, qnr, sul1, intl1, arsC, and merA. These genes conferred resistance to multiple antibiotics such as beta-lactams, aminoglycosides, tetracyclines, quinolones, sulfonamides, and heavy metals.

Gene Information

Gene Name: dfr7
Allele: dfr7
Encodes: dihydrofolate reductase
Source Database: Reslit
Confers Resistance To: trimethoprim
Organisms Tested In: • Avian pathogenic Escherichia coli
Geographic Location: China
Validation Method: PCR screening and DNA sequencing

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dfr7

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dfr7

Gene Information