Browse AMR Genes
Explore antimicrobial resistance genes from the literature
Explore antimicrobial resistance genes from the literature
trimethoprim-resistant dihydrofolate reductase DfrB2
Overview
| Allele | Database | Papers | Drug Classes | Organisms | Countries | Years | Sequence Accession | Protein Accession |
|---|---|---|---|---|---|---|---|---|
| DfrB2 | Card DatabaseReference Gene CatalogResFinder DatabaseReslit | 8 | TRIMETHOPRIM, trimethoprim | Pseudomonas aeruginosa +1 | Russia|Moscow, Bulgaria | 2002, 2020, 2021, 2024 | AY553333.1 | AAT49071.1 |
| dfrB2 | Card DatabaseResFinder Database | 2 | TRIMETHOPRIM | uncultured bacterium +1 | - | 1981 | DQ839391.1 | ABI20482.1 |
| dfr B2 | Reslit | 1 | trimethoprim | Pseudomonas aeruginosa | Pakistan | 2021 | JADDMB000000000|JADDMA000000000|JADEYD000000000|JADDLZ000000000|JADDLY000000000|JADDLX000000000|PRJNA669539|PRJNA670459 | - |
Characterization and movement of the class 1 integron known as Tn2521 and Tn1405.
Characterization and movement of the class 1 integron known as Tn2521 and Tn1405.
Characterization and movement of the class 1 integron known as Tn2521 and Tn1405.
Engineering a CRISPR Interference System To Repress a Class 1 Integron in Escherichia coli.
The study demonstrates that a CRISPRi system can effectively repress the class 1 integron in E. coli, significantly reducing antibiotic resistance and horizontal gene transfer of ARGs.
CRISPR Element Patterns vs. Pathoadaptability of Clinical Pseudomonas aeruginosa Isolates from a Medical Center in Moscow, Russia.
The study identified multiple antibiotic resistance genes in clinical Pseudomonas aeruginosa isolates, including blaVIM-2, blaOXA-396, blaOXA-488, floR, tetG, sul1, dfrA5, dfrB2, dfrB5, aph(3)-Ib, blaPAO, catB7, and fosA, which confer resistance to various antibiotics such as beta-lactams, chloramphenicol, tetracycline, sulfonamides, trimethoprim, aminoglycosides, and fosfomycin.
Antimicrobial Resistance and Genomic Characterization of Six New Sequence Types in Multidrug-Resistant Pseudomonas aeruginosa Clinical Isolates from Pakistan.
The study identified 13 acquired antibiotic resistance genes in six new sequence types of multidrug-resistant Pseudomonas aeruginosa isolates from Pakistan, including beta-lactamases, aminoglycoside-modifying enzymes, and others. Mutations in the pmrA gene were also found to contribute to colistin resistance.
Genomic Insights into Vietnamese Extended-Spectrum β-Lactamase-9-Producing Extensively Drug-Resistant Pseudomonas aeruginosa Isolates Belonging to the High-Risk Clone ST357 Obtained from Bulgarian Intensive Care Unit Patients.
The study identified multiple AMR genes, including blaVEB-9, blaPDC-3, blaOXA-10, blaOXA-50, and others, in two extensively drug-resistant Pseudomonas aeruginosa isolates from Bulgaria. These genes conferred resistance to various antibiotics, including β-lactams, aminoglycosides, and fluoroquinolones.
DNA sequence of a plasmid-encoded dihydrofolate reductase.
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