dfria

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dihydrofolate reductase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

UniProt

Protein entries specific to dfria

AMR Rules

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Validation StatusCandidate

Overview

Mechanism: reduction of dihydrofolate
Validation Method: PCR and phenotypic testing
Drug Classes: trimethoprim
Organisms: Escherichia coli
Geographic Location: India
Papers: 1
Databases: Reslit

Papers1

Higher prevalence of multidrug-resistant extended-spectrum β-lactamases producing Escherichia coli in unorganized pig farms compared to organized pig farms in Mizoram, India.

PMID 33487994 · 2020

The study identified several AMR genes, including bla TEM, bla CTX-M, bla CMY, tetA, tetB, sul1, sul2, aadA, and dfrIa, in multidrug-resistant E. coli isolates from both organized and unorganized pig farms in Mizoram, India.

Gene Information

Gene Name: dfria
Allele: dfrIa
Encodes: dihydrofolate reductase
Source Database: Reslit
Mechanism: reduction of dihydrofolate
Confers Resistance To: trimethoprim
Organisms Tested In: • Escherichia coli
Geographic Location: India
Validation Method: PCR and phenotypic testing

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dfria

Gene Information

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dfria

Gene Information