Browse AMR Genes

Explore antimicrobial resistance genes from the literature

dgcJ

diguanylate cyclase

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to dgcJ

Browse AMR rules for dgcJ

Overview

Drug Classes: kanamycin
Organisms: E. coli
Papers: 1
Mutations: 1

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
L152R	-	-	E. coli	kanamycin	Reslit	Candidate

Papers1

1

Efflux-linked accelerated evolution of antibiotic resistance at a population edge.

PMID 36400010 · 2022

DgcJ mutations are associated with kanamycin resistance.

Mutation Information

Protein Change: L152R
Organisms: E. coli
Confers Resistance To: kanamycin
Validation Method: mutant isolation and MIC testing
Source Database: Reslit