Browse AMR Genes

Explore antimicrobial resistance genes from the literature

dhfr

NCBI Pathogen Isolates

Bacterial genomes carrying this gene

NCBI Reference Gene Catalog

Known alleles and reference sequences

Protein entries specific to dhfr

Browse AMR rules for dhfr

Overview

Drug Classes: pyrimethamine
Organisms: Plasmodium falciparum
Papers: 1
Mutations: 5

Mutations

Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
A16V	-	-	Plasmodium falciparum	pyrimethamine	ResFinder Database	Candidate
N51I	-	-	Plasmodium falciparum	pyrimethamine	ResFinder Database	Candidate
C59R	-	-	Plasmodium falciparum	pyrimethamine	ResFinder Database	Candidate
S108N	-	-	Plasmodium falciparum	pyrimethamine	ResFinder Database	Candidate
I164L	-	-	Plasmodium falciparum	pyrimethamine	ResFinder Database	Candidate

Papers1

1

Mutation Information

dhfr: p.A16V dhfr: p.N51I dhfr: p.C59R dhfr: p.S108N dhfr: p.I164L

Protein Change: A16V, N51I, C59R, S108N, I164L
Organisms: Plasmodium falciparum
Confers Resistance To: pyrimethamine
Source Database: ResFinder Database