dinF

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MATE family efflux pump

NCBI Pathogen Isolates

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UniProt

Protein entries specific to dinF

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Validation StatusCandidate

Overview

Validation Method: mutant construction and susceptibility testing
Drug Classes: quinolones
Organisms: Streptococcus pneumoniae
Papers: 1
Databases: Reslit

Papers1

Functional analysis of pneumococcal drug efflux pumps associates the MATE DinF transporter with quinolone susceptibility.

PMID 23114782 · 2013

The study identifies DinF as a MATE family efflux pump involved in quinolone susceptibility in Streptococcus pneumoniae, showing that its inactivation increases susceptibility to moxifloxacin, ciprofloxacin, and levofloxacin.

Gene Information

Gene Name: dinF
Allele: dinF
Encodes: MATE family efflux pump
Source Database: Reslit
Confers Resistance To: quinolones
Organisms Tested In: • Streptococcus pneumoniae
Validation Method: mutant construction and susceptibility testing

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dinF

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dinF

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