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Explore antimicrobial resistance genes from the literature
chaperone
Overview
Functional characterization of the chaperone DnaK of Riemerella anatipestifer in antibiotic resistance and pathogenicity.
The DnaK chaperone of Riemerella anatipestifer contributes to antibiotic resistance by reducing oxidative stress and maintaining cell morphology. Deletion of dnaK increases susceptibility to several antibiotics and impairs pathogenicity.
The chaperone DnaK promotes the emergence and accumulation of antibiotic-resistant clones through its ATPase activity in Riemerella anatipestifer.
The study shows that the chaperone DnaK promotes the emergence and accumulation of antibiotic-resistant clones in Riemerella anatipestifer through its ATPase activity. Deletion of dnaK reduces the frequency of antibiotic resistance mutations, and the DnaK inhibitor telaprevir decreases the frequency of resistant clones.
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